Search results for "EPA"
showing 10 items of 8995 documents
Clinical and economic impact of infliximab one-hour infusion protocol in patients with inflammatory bowel diseases: A multicenter study
2017
AIM To assess the impact of short infliximab (IFX) infusion on hospital resource utilization and costs. METHODS All inflammatory bowel diseases (IBD) patients who received IFX 1 h infusion from March 2007 to September 2014 in eight centers from Southern Italy were included in the analysis. Demographic, clinical and infusion related data were collected. The potential benefits related to the short infusion protocol were assessed both in terms of time saving and increased infusion unit capacity. In addition, indirect patient-related cost savings were evaluated. RESULTS One hundred and twenty-five patients were recruited (64 with ulcerative colitis and 61 with Crohn’s disease). Median duration …
Correlative histologic and arthroscopic evaluation in rheumatoid knee joints.
1992
The correlation between arthroscopic observations and histologic changes in rheumatoid arthritis is still controversial. Synovial samples of 21 knee joints in rheumatoid arthritis patients were comparatively investigated by endoscopy and histology. Biopsies were scored by an endoscopist and subsequently dissected. Different histochemical and immunocytochemical staining techniques were used to define inflammatory activity. Arthroscopic and histological values were compared by rating scales and variance analysis. Our study indicates that synovial biopsy is of diagnostic value in rheumatoid arthritis. However, its usefulness depends on the histochemical methods used. The results revealed highl…
MINIMIZING INFLIXIMAB TOXICITY IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASE
2008
Abstract Background Infliximab is a widely used biological agent for the treatment of inflammatory bowel disease, and has a favorable risk/benefit ratio. Aim It is useful to know that patients treated with infliximab are exposed to developing adverse events that could be reduced with a prudent and a rational clinical approach and by optimizing the treatment protocol. Methods PubMed (including Epub) was searched in October 2006 and again in March 2007. Results The high immunogenic potential of infliximab determines the antibodies that inhibit the effect of infliximab and the appearance of subsequent acute and delayed infusion reactions. Infliximab has an immunomodulatory effect, thus increas…
Treatment of Combined Medial and Lateral Collateral Ligament Insufficiency
2016
The medial and lateral collateral ligament complexes represent primary elbow ligament stabilizers. Injury to these structures may occur because of an elbow dislocation or due to a severe varus or valgus force. Most elbow dislocations are stable once reduced and may be treated conservatively. However, if the elbow remains unstable surgical treatment is recommended. Repair should be anatomical and should restore stability to the elbow in order to permit an early active range of motion. Reconstruction may be required in severe cases and where primary repair is not possible. Depending on the degree of instability, either one or both of the collateral ligament complexes may need to be repaired o…
Treatment with a CO-releasing molecule (CORM-3) reduces joint inflammation and erosion in murine collagen-induced arthritis.
2008
Contains fulltext : 70589.pdf (Publisher’s version ) (Closed access) OBJECTIVE: CO-releasing molecules (CO-RMs) are a novel class of anti-inflammatory agents. We have examined the possible therapeutic effects of CORM-3 in collagen-induced arthritis (CIA). METHODS: Arthritis was induced in DBA-1/J mice by type II collagen. Animals were treated with CORM-3 (5 and 10 mg/kg/day, intraperitoneally) or the inactive compound iCORM-3 (10 mg/kg/day, intraperitoneally) unable to release CO, from days 22 to 31. Production of anti-type II collagen antibodies, cytokines and cartilage olimeric matrix protein (COMP) was evaluated by enzyme-linked immunosorbent assay, and prostaglandin E(2) (PGE(2)) by rad…
Ģimenes ārsta otrās māsas programmas iespējas mazināt nelietderīgus neatliekamās medicīnas palīdzības dienesta izsaukumus un slimnīcu uzņemšanas noda…
2019
Maģistra darbā ir pētīta tēma “Ģimenes ārsta otrās māsas programmas iespējas mazināt nelietderīgus neatliekamās medicīnas palīdzības dienesta izsaukumus un slimnīcu uzņemšanas nodaļu apmeklējumus”. Ģimenes ārstu otrās māsas programma Latvijā ir ieviesta, lai uzlabotu primārās veselības aprūpes (PVA) sistēmu. Mērķis ir veicināt iedzīvotāju veselību un apmierināt sabiedrības vajadzības. Papildus finansējums tiek nodrošināts, lai otrā māsa tiktu piesaistīta tām ģimenes ārsta praksēm, kurās pacientu skaits ir lielāks par 1800. Daudzās valstīs (arī Latvijā) tiek novērots, ka cilvēki aizvien biežāk tā vietā lai saņemtu palīdzību pie sava ģimenes ārsta, izvēlās to saņemt neatliekamās palīdzības me…
"When girls don't have to work that much they are doing better in school" : ethnographic case study on girls participation in Nepalese village school
2013
Tiivistelmä: Naiset elävät nepalilaisessa kulttuurissa alisteisessa asemassa. Naisten sorrettu asema näkyy selkeästi muun muassa koulutussektorilla, keskimäärin naiset ovat miehiä vähemmän koulutettuja. Tähän epäkohtaan on pyritty puuttumaan erilaisin kansallisin ja kansainvälisin ohjelmin, mikä on johtanut peruskoulutukseen osallistuvien tyttöjen lukumäärän merkittävään kasvuun. Tässä tutkimuksessa tarkastelin tyttöjen osallistumista nepalilaisessa kyläkoulussa. Tutkimus on etnografinen tapaustutkimus, jonka myötä tutustuin opettajien ja tyttöjen väliseen vuorovaikutukseen opetustilanteissa. Lisäksi tutkin tyttöjen osallisuutta toimijuuden ja voimaantumisen näkökulmista ja pohdin löydöksiä…
Agency of rural Nepali women as moderated by community learning centres : a postcolonial feminist perspective
2017
This study includes the voices and experiences of fifteen Nepali women who participated in the activities provided at two Community Leaning Centres (CLCs). CLCs provide various learning activities for the women in rural Nepal, where education opportunities for adult women are extremely lacking. Situated within a postcolonial feminist perspective, this thesis aims to investigate not only the benefits of the CLCs for women per se but the construction of women’s agency through the learning using a combination of semi-structured interviews and a thematic data analysis. This study identifies the perceived benefits of women participants and analyses the processes by which women negotiate social c…
Naisena miesten maailmassa: naiset asepalveluksessa
1999
Naisten asema ja rooli Puolustusvoimissa
2020
”Mikä sai naisen lähtemään armeijaan?” Kysymys toistui useampaan otteeseen vuoden aikana suorittaessani naisten vapaaehtoista asepalvelusta. Astuin palvelukseen vuoden 2000 heinäkuussa, jolloin naisia oli ollut varusmiehinä vajaat viisi vuotta. Tänä vuonna naisten vapaaehtoisen asepalveluksen mahdollistavan lain voimaantulosta ja ensimmäisten naisten palvelukseen astumisesta tulee kuluneeksi kaksikymmentäviisi vuotta. Se on samalla sekä pitkä että lyhyt aika. Paljon on muuttunut siitä, kun itse palvelin varusmiehenä. Nainen on kuitenkin sotilaana yhä erikoisuus: aiheesta keskustellaan, sitä joutuu perustelemaan ja edelleen on niitä, joiden mielestä nainen ei kuulu armeijaan tai sotilaaksi. …