Search results for "EPO"

showing 10 items of 6062 documents

Coscinolactams A and B: new nitrogen-containing sesterterpenoids from the marine sponge Coscinoderma mathewsi exerting anti-inflammatory properties

2009

Abstract Investigation of the marine sponge Coscinoderma mathewsi led to the isolation of two novel nitrogen-containing cheilanthane sesterterpenoids, coscinolactams A and B, together with known suvanine. The structures were elucidated by extensive spectroscopic measurements including NOE experiments to deduce the stereochemistry. The natural compounds, as well as a semisynthetic derivative, showed moderate anti-inflammatory activity measured as their capability to inhibit PGE2 and NO production. The suvanine aldehyde derivative 4 inhibited inducible nitric oxide protein expression with an IC50 value of 7.3 μM.

EXTRACTIONmedicine.drug_classStereochemistrySesterterpenoidsBiochemistryAldehydeAnti-inflammatorySesterterpenesNitric oxidechemistry.chemical_compoundAnti-inflammatory activityEPONGESpongeDrug DiscoverymedicineOrganic chemistryIC50ACTIVITE ANTIINFLAMMATOIREchemistry.chemical_classificationTESTACTIVITE BIOLOGIQUEbiologyOrganic ChemistryINVERTEBRE AQUATIQUEbiology.organism_classificationTerpenoidSpongechemistrySUBSTANCE NATURELLEDerivative (chemistry)
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A lacustrine record of the early stage of the Miocene Climatic Optimum in Central Europe from the Most Basin, Ohře (Eger) Graben, Czech Republic.

2014

AbstractThis study reports on a ~ 150 m thick macrofossil-barren sequence of siliciclastic sediments from a Burdigalian age (Early Miocene) freshwater lake. The lake was located within an incipient rift system of the Most Basin in the Ohře (Eger) Graben, which was part of the European Cenozoic Rift System, and had an original area of ≈ 1000 km2. Sediments from the HK591 core that cover the entire thickness of the lake deposits and some of the adjacent stratigraphic units were analysed by X-ray fluorescence spectroscopy (a proxy for element composition) and magnetic polarity measurement. The element proxies were subjected to frequency analysis, which provided estimated sedimentation rates, a…

Early MioceneMilankovitch cyclesRiftOrbital forcinglake sedimentsclimate dynamicsGeologyCyclostratigraphyBiostratigraphy[ SDU.STU.ST ] Sciences of the Universe [physics]/Earth Sciences/StratigraphySedimentary depositional environmentGrabenPaleontology13. Climate action[SDU.STU.ST]Sciences of the Universe [physics]/Earth Sciences/StratigraphyMilankovitch cyclescyclostratigraphyGeologyMagnetostratigraphy
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Atmospheric Lead Deposition into Guarapina Lagoon, Rio de Janeiro State, Brazil

1988

The rate of anthropogenic mobilization of heavy metals is higher than the natural supply to the sedimentary environments. I n rivers, lakes and various other terrestrial areas, the drastic increase of heavy metals has been accredited to human activity (Tyler 1972). Erlenkeuser et al. (1974) suggest that Cd, Pb, Zn and Cu in the upper sediment sequence of sediment cores collected from Kiel Bight in the Baltic Sea, are the result of fossil fuel use in industries. Such assemblages have been identified in North America by Goldberg et al. (1977, 1979) from both coastal regions. Sediment cores taken from the deepest part of lakes and lagoons have been analysed to study the historical development …

East coastOceanographyBaltic seaLead (sea ice)Environmental scienceSedimentHeavy metalsSedimentary rockPrecipitationDeposition (geology)
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Cryptic diversity, niche displacement and our poor understanding of taxonomy and ecology of aquatic microorganisms

2022

AbstractThe analysis of ecological niche is an important task to correctly identify the role exerted by species within ecosystems, to assess their vulnerability, to plan effective measures addressed at fulfilling the postulates of biological conservation, and ultimately to prevent biodiversity loss. However, for the majority of organisms our knowledge about the actual extent of their ecological niche is quite limited. This is especially true for microscopic organisms. Evidence exists that in different geographical areas allegedly conspecific populations can show different, if not antithetical, ecological requirements and not-overlapping ecological niches. This opinion paper discusses whethe…

Ecological shortfallsSettore BIO/07 - EcologiaLinnean shortfallRotifersPhytoplanktonSettore BIO/03 - Botanica Ambientale E ApplicataSettore BIO/05 - ZoologiaCharacter displacementAquatic ScienceDiaptomid copepods
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Growth of pikeperch in relation to lake characteristics: total phosphorus, water colour, lake area and depth

2003

The growth of pikeperch Sander lucioperca was studied in 41 lakes in central Finland. The backcalculated average total length of 3 year-old pikeperch was used as an indicator of growth. The growth correlated positively with total phosphorus and water colour and negatively with lake area and depth. The reason for differences in growth may be differences in the amount of suitable food, foraging success or temperature dynamics in different lakes.

EcologyPhosphorusForagingEnvironmental factorchemistry.chemical_elementAquatic ScienceBiologymedicine.disease_causebiology.organism_classificationAnimal sciencePercidaechemistryRepoblaciónmedicineTotal phosphorusSpatial variabilityWater qualityEcology Evolution Behavior and SystematicsJournal of Fish Biology
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Loss of a freshwater copepod species from El Junco Lake, Galápagos following the introduction and eradication of the Nile tilapia

2021

An undescribed diaptomid copepod probably belonging to a new Mastigodiaptomus species has been discovered and was very abundant in El Junco Lake (San Cristóbal Island, Ecuador) from 1966 until 2004. The species was not found in samples from 2007, 2008 or 2018. The loss of this key species from the lake coincides with the illegal introduction of Nile tilapia to El Junco Lake in 2005 and its subsequent eradication in 2008. The disappearance of this biogeographically and ecologically important copepod population may be explained by direct mechanisms of predation and competition, by a combination of both processes, and by indirect mechanisms linked to alterations in the lake ecosystem. The effe…

EcologybiologyOreochromiscopepodbiological invasionsSettore BIO/05 - ZoologiaZoologynon-native speciesAquatic Sciencebiology.organism_classificationInvasive speciesPREDAÇÃO (BIOLOGIA)rotenoneOreochromisNile tilapiaGeographynon-native fishJuncoDiaptomidCopepodNature and Landscape Conservation
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Development of a TaqMan PCR assay for the identification of the non-native copepod Acartia tonsa, and detection of this species in Norwegian coastal …

2021

Abstract Molecular based assays for detection of species are a powerful tool to supplement morphological methods that may be time and labor intensive. Here we describe a sensitive TaqMan real time polymerase chain reaction assay that specifically detects the presence of Acartia tonsa in mixed plankton samples. The assay is used to find this non-native copepod in samples collected in Norwegian coastal waters.

Ecologybiologyved/biologyfungiPcr assayved/biology.organism_classification_rank.speciesZoologyAquatic Sciencebiology.organism_classificationTaqManIdentification (biology)Ecology Evolution Behavior and SystematicsCopepodAcartia tonsaJournal of Plankton Research
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Copepod limnocalanus macrurus mating in relation to vertical migrations and aspects of feeding rates in the Bothnian Sea (Baltic Sea)

2006

The studies of calanoid copepod Limnocalanus macrurus feeding rates and mating related to vertical migration were conducted in October 2005 in the Bothnian Sea. The monocyclic copepod Limnocalanus macrurus develops mostly to adult and larger copepodites stages in autumn and these stages were investigated. Bothnian Sea is a brackish-water basin in Baltic Sea with comparatively big depth therefore Limnocalanus macrurus which prefer to live in deep and cold water is more abundant in this Baltic Sea part. Recent observations in the Bothnian Sea showed that Limnocalanus macrurus performs diel vertical migrations and adults approve stricter tendency to stay under thermocline layer at night than c…

Ecologymedia_common.quotation_subjectLimnocalanus macrurusBiologybiology.organism_classificationOceanographyBaltic seaMatingReproductionThermoclineClearance rateDiel vertical migrationCopepodmedia_common2006 IEEE US/EU Baltic International Symposium
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Bases para el análisis económico de los sistemas de compliance penal

2019

Compliance programs and systems of criminal or administrative liability are being increasingly adopted by different countries as measures meant to reduce the social cost of white collar criminality. However, the legal application of these measures does not always ponder correctly the impacts on common good, the levels of economic activity and the adequate functioning of markets of goods and services. Eventually, this situation can lead to undesired effects, such as the inefficiency of the criminal system, the reduction of economic activity or the arising of obstacles to competition. By taking these circumstances into account, in this paper we will utilize the Economic Analysis of Law to ana…

Economic efficiencyPublic economicsDelitos Económicosmedia_common.quotation_subjectSocial costLiabilityComputingMilieux_LEGALASPECTSOFCOMPUTINGGeneral MedicineResponsabilidad Penal de las Personas JurídicasCompetition (economics)Promotion (rank)IncentiveGoods and servicesAnálisis Económico del Derecho Penal//purl.org/pe-repo/ocde/ford#5.05.00 [https]BusinessInefficiencymedia_commonCompliance
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Unholy alliance or way of the future?

2021

This chapter observes how recent Finnish municipal and regional cultural strategies signify and value culture. On the basis of a thematic analysis of 21 strategies, I construct three main categories of their 'culture speech': the first is to approach culture as an instrument that unites different administrative sectors, on the one hand, and helps them to achieve extra-cultural – mostly social and economic – objectives, on the other. The second, is where culture is attached to individuals and communities and their expressions. It is also seen as an 'instrument' benefitting and serving them. The third, is economic. Culture is associated with the cultural and creative industries, and with econ…

Economic growthAlliancePolitical sciencekulttuuripolitiikkakulttuuriteollisuuskuntasuunnitteluyhdyskuntasuunnittelualuekehityskaupunkisuunnitteluCommunity developmentaluepolitiikkakulttuurituotanto
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