Search results for "EPO"

showing 10 items of 6062 documents

LINQ modeļu repozitorijiem

2016

Modeļu vadīta pieeja programmatūras izstrādes pasaulē pēdējā laikā kļūst arvien populārāka un attiecīgi arī aug pieprasījums pēc rīkiem, kas spēj efektīvi strādāt ar modeļiem. “LINQ modeļu repozitorijiem” darba ietvaros uzmanība tiek pievērsta iespējām strādāt ar modeļu repozitorijiem .NET satvarā C# programmēšanas valodā. Darbā tiek izpētītas LINQ adapteru izstrādes iespējas, modeļu repozitoriju piekļuves iespējas un izstrādāts LINQ adapteris modeļu repozitorijiem, kas balstās uz universālu RA API, kas ļauj izmantot dažādus modeļu repozitorijus, piemēram, populāro EMF.

modeļu repozitorijiDatorzinātne.NET C#RA APILINQ
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Late Pleistocene vertebrate - bearing deposits at San Teodoro Cave (North-Eastern Sicily): Preliminary data on faunal diversification and chronology

2008

Abstract This paper deals with the chronology and the possible correlations among levels of different excavated areas in the Pleistocene vertebrate-bearing deposits at the large San Teodoro Cave (North-Eastern Sicily). Two trenches have been excavated along the eastern side of the cave, located at a distance from the entrance, respectively, of 8 m ( α trench) and 28 m ( β trench) and at different depths. Lithological features, biometrical data from small mammals and ecological data from molluscs point to similar environmental conditions for the α trench deposits and those located along the eastern wall of the cave in the eastern part of the β trench. The same evidence, and the taphonomic fe…

molluscslate pleistocenegeographyTaphonomygeography.geographical_feature_categoryPleistocenebiologyVertebrateSettore GEO/01 - Paleontologia E PaleoecologiaArchaeologylate pleistocene; molluscs; sicily; vertebratesPaleontologyCavebiology.animalTrenchsicilyLate Pleistocene Sicily Vertebrates Chronology Cave depositsvertebratesMediterranean IslandsGeologyEarth-Surface ProcessesStratumChronology
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Oxygen Atom Transfer Catalysis by Dioxidomolybdenum(VI) Complexes of Pyridyl Aminophenolate Ligands

2021

A series of new cationic dioxidomolybdenum(VI) complexes [MoO2(Ln)]PF6 (2-5) with the tripodal tetradentate pyridyl aminophenolate ligands HL2-HL5 have been synthesized and characterized. Ligands HL2-HL4 carry substituents in the 4-position of the phenolate ring, viz. Cl, Br and NO2, respectively, whereas the ligand HL5, N-(2-hydroxy-3,5-di-tert-butylbenzyl)-N,N-bis(2-pyridylmethyl)amine, is a derivative of 3,5-di-tert-butylsalicylaldehyde. X-ray crystal structures of complexes 2, 3 and 5 reveal that they have a distorted octahedral geometry with the bonding parameters around the metal centres being practically similar. Stoichiometric oxygen atom transfer (OAT) properties of 5 with PPh3 wer…

molybdenumkatalyytittripodal tetradentate ligandepoxidationoxygen atom transferkompleksiyhdisteetmolybdeeni
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Monetary information in sustainability reports: How is it related with stakeholders?

2014

Sustainability reports have recently become a central tool for a corporation in convincing different stakeholder of their sustainability performance. The research and especially criticism towards sustainability reports is increasing. One solution for the criticism would be that companies provide more monetary arguments of their sustainability work. Currently there is a research gap of the content of the monetary sustainability reporting. This paper aims to address this gap by analysing how three Finnish companies construct the classification of stakeholders in terms of monetary information in their sustainability reports between 2003 and 2012. We studied three Finnish companies which repres…

monetary informationkestävä kehityssidosryhmätsustainability reportsrahamääräiset tiedotstakeholdersviestintä
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"Hyvä mahdollisuus meikäläiselle, joka ei voi ihan kilpailla suomalaisten kanssa" : valtion apurahat monikulttuurisiin taidehankkeisiin : taiteen edi…

2013

”Hyvä mahdollisuus meikäläiselle, joka ei voi ihan kilpailla suomalaisten kanssa” Valtion apurahat monikulttuurisiin taidehankkeisiin: taiteen edistämistä vai kotouttamispolitiikkaa? Katri Talaskivi Pro gradu -tutkielma Yhteiskuntapolitiikka / kulttuuripolitiikan maisteriohjelma Yhteiskuntatieteiden ja filosofian laitos Jyväskylän yliopisto Ohjaaja Miikka Pyykkönen Syksy 2013 86 sivua + 3 liitettä Tämä pro gradu -tutkielma käsittelee niitä haasteita, joita ulkomaalaistaustaiset taiteilijat kokevat kohdanneensa pyrkiessään suomalaiselle taiteen kentälle, sekä sitä, millaisiin tarpeisiin valtion apurahat monikulttuurisiin taidehankkeisiin heidän mielestään vastaavat. Tutkielman kvalitatiivine…

monikulttuurisuustaiteilijatulkomaalaisettaidepolitiikkakulttuuripolitiikkaSuomiapurahatpositiivinen erityiskohtelutaiteen tukeminentaideapurahatmaahanmuuttajat
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What about cultural policy? : interdisciplinary perspectives on culture and politics

2009

monitieteisyysAssociations institutions etckulttuuripolitiikkaKangas AnitaSpaceProduction (Economic theory)taidekulttuuripolitikkatoimintaympäristöPolitics and culturekulttuurituottajatAuthorshipArt and statekulttuuritaidepolitiikkatieteidenvälisyysConsumption (Economics) in arttutkimustiedepolitiikkatilaCultural policykulttuurintutkimuskulttuurituotanto
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El fenómeno senderista en España. Análisis por un panel de expertos

2014

El fenómeno senderista en España. Análisis por un panel de expertos. El senderismo se ha convertido en una de las actividades físico-recreativas más importantes de nuestra sociedad. Los enfoques de práctica superan las motivaciones deportivas para incorporar objetivos turísticos, de calidad de vida, de movilidad no motorizada o del desarrollo rural, por citar algunos ejemplos. Por otra parte, el senderismo admite actividades afines (excursionismo, caminata, trekking, paseo,…) y coexiste perfectamente con otras prácticas complementarias (carreras de montaña, vías ferratas, Btt, equitación,…) que le convierten en un verdadero fenómeno social. Frente una actividad de tal envergadura y transcen…

movilidad no motorizadacaminos naturalesgestión deportivaclub de montañaespacios naturalesUNESCO::CIENCIAS ECONÓMICAS::Organización y dirección de empresasmontañismoalojamientosUNESCO::SOCIOLOGÍAVías verdesmovilidad pedrestre:PEDAGOGÍA::Organización y planificación de la educación [UNESCO]fenómeno socialocio y deportemovilidad urbanaturismo de montañaexcursionismo:CIENCIAS ECONÓMICAS::Organización y dirección de empresas ::Marketing [UNESCO]trekking:SOCIOLOGÍA [UNESCO]tiempo libreUNESCO::PEDAGOGÍA::Organización y planificación de la educaciónUNESCO::CIENCIAS ECONÓMICAS::Organización y dirección de empresas ::Marketingsenderismoturismoturismo deportivo:CIENCIAS ECONÓMICAS::Organización y dirección de empresas [UNESCO]
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Estudio comparado entre el impacto de la política migratoria estadounidense sobre la Frontera Norte de México y la política migratoria española sobre…

2020

A través de este trabajo, se pretende mostrar los resultados de la investigación sobre el terreno llevada a cabo en la ciudad fronteriza de Tijuana y algunos puntos clave de la frontera norte de México con Estados Unidos ubicados en la región de Baja California y California, para compararlos con los obtenidos en el estudio realizado en las ciudades autónomas de Ceuta y Melilla, además de otras localidades cercanas a la frontera sur de España con Marruecos. Su finalidad es establecer hasta qué punto el control de fronteras ha condicionado el patrón de desplazamientos de migrantes irregulares hacia estos países, y cuáles han sido sus consecuencias en las regiones fronterizas. Así, en primer l…

muroscontrol de fronterasFrontera Norte EE.UU-Méxicomigración irregular:SOCIOLOGÍA [UNESCO]securitizaciónayuda humanitariamigraciónpolítica migratoriaFrontera Sur España-MarruecosUNESCO::SOCIOLOGÍAsociedad civildeportacionesvallasderechos humanos
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Myotonic dystrophy: candidate small molecule therapeutics

2017

Myotonic dystrophy type 1 (DM1) is a rare multisystemic neuromuscular disorder caused by expansion of CTG trinucleotide repeats in the noncoding region of the DMPK gene. Mutant DMPK transcripts are toxic and alter gene expression at several levels. Chiefly, the secondary structure formed by CUGs has a strong propensity to capture and retain proteins, like those of the muscleblind-like (MBNL) family. Sequestered MBNL proteins cannot then fulfill their normal functions. Many therapeutic approaches have been explored to reverse these pathological consequences. Here, we review the myriad of small molecules that have been proposed for DM1, including examples obtained from computational rational …

musculoskeletal diseases0301 basic medicineTherapeutic gene modulationcongenital hereditary and neonatal diseases and abnormalitiesMutantComputational biologyBiologyMyotonic dystrophyMyotonin-Protein Kinase03 medical and health sciences0302 clinical medicineTrinucleotide RepeatsDrug DiscoveryGene expressionmedicineAnimalsHumansMyotonic DystrophyGenePharmacologyRegulation of gene expressionGeneticsDrug RepositioningRational designmedicine.diseaseSmall moleculeHigh-Throughput Screening Assays030104 developmental biologyGene Expression RegulationDrug Design030217 neurology & neurosurgeryDrug Discovery Today
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Case Report: Unmasking Hypercalcemia in Patients With Neuroendocrine Neoplasms. Experience From Six Italian Referral Centers

2021

BackgroundHypercalcemia is a common paraneoplastic syndrome which can occur in up to 10% of patients with advanced neoplasms. Paraneoplastic parathyroid hormone-related protein (PTHrP) represents the most frequent cause of this syndrome. In neuroendocrine neoplasms (NENs) paraneoplastic hypercalcemia is rare.Case SeriesThe present series includes all patients with NENs and paraneoplastic hypercalcemia from four Italian centres: (I) A 40-year-old man was hospitalized for repeated episodes of falls, hyposthenia and drowsiness. Severe hypercalcemia was found. Metastatic pancreatic G2 NEN and PTHrP-related hypercalcemia were diagnosed. The patient started therapy with somatostatin analogs (SSA)…

musculoskeletal diseasesAdultMalemedicine.medical_specialty125-dihydroxyvitamin Dbronchial carcinoidEndocrinology Diabetes and Metabolism1pancreatic NENCase ReportGastroenterologyDiseases of the endocrine glands. Clinical endocrinologyparaneoplastic hypercalcemia; parathyroid hormone-related protein; pancreatic nen; bronchial carcinoid; 125-dihydroxyvitamin dEndocrinologyparaneoplastic hypercalcemiaInternal medicinemedicineHumansVitamin DAgedEverolimusmedicine.diagnostic_testPerformance statusParathyroid hormone-related proteinbusiness.industryparathyroid hormone-related proteinMiddle AgedRC648-665PrognosisPancreatic NeoplasmsNeuroendocrine TumorsSomatostatinDenosumabPositron emission tomographyCalcitoninRadionuclide therapyHypercalcemiaFemalebusiness25-dihydroxyvitamin dhormones hormone substitutes and hormone antagonistsmedicine.drugFrontiers in Endocrinology
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