Search results for "EPOR"

showing 10 items of 2839 documents

Imaging features of perineural and perivascular spread in rapidly progressive rhino-orbital-cerebral mucormycosis: A case report and brief review of …

2021

Background: Rhinocerebral mucormycosis (ROCM) is an opportunistic fungal infection originating from the paranasal sinuses with extension to the brain. A delayed diagnosis can rapidly result in a poor prognosis. ROCM commonly affects patients with diabetes or immunocompromised states with a variable progression. Case Description: We report the case of a 59-year old patient with an untreated diabetes who developed a ROCM with rapidly progressive neurological symptoms. From the onset of sinus pain, nasal congestion, he rapidly developed facial swelling and masticatory dysfunction. The patient underwent sinus surgery which allowed Rhizopus oryzae to be isolated. Accordingly, a systemic therapy…

0301 basic medicinemedicine.medical_specialtyPerivascular spread030106 microbiologyCase ReportNasal congestionMucormycosi03 medical and health sciences0302 clinical medicineZygomycosisPerineural spreadAmphotericin BDiabetes mellitusOcclusionmedicineMucormycosisbusiness.industryMucormycosisRhinocerebral mucormycosimedicine.diseaseThrombosisSurgeryParanasal sinusesmedicine.anatomical_structureRhinocerebral mucormycosisSurgeryMucormycosis; Perineural spread; Perivascular spread; Rhinocerebral mucormycosis; ZygomycosisNeurology (clinical)Zygomycosismedicine.symptombusiness030217 neurology & neurosurgerymedicine.drug
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Exercise and Conjugated Linoleic Acid Supplementation Induce Changes in the Composition of Liver Fatty Acids

2019

Exercise and supplementation with conjugated linoleic acid (CLA) are used to reduce body weight and to improve health. Applied together, they may exert a synergistic effect. However, the effects of exercise and CLA supplementation on liver metabolism are poorly understood. The aim of this study was to examine the influence of exercise and CLA supplementation on fatty acids (FA) composition in mouse liver. We analyzed 44 of known FAs of this organ by gas chromatography-mass spectrometry. Our results demonstrated that exercise contributed to a decrease in odd-chain FA and an increase in n-6 polyunsaturated FA contents. In turn, CLA stimulated an increase in branched-chain FAs and n-3 polyunsa…

0301 basic medicinemedicine.medical_specialtyPhysiologyConjugated linoleic acid030209 endocrinology & metabolismHealth benefitslivermyokinelcsh:Physiologyconjugated linoleic acid03 medical and health scienceschemistry.chemical_compound0302 clinical medicineInternal medicinePhysiology (medical)MyokinemedicineFatty acid synthesisfatty acid liver exercise myokine conjugated linoleic acidchemistry.chemical_classificationlcsh:QP1-981exerciseintegumentary systemfood and beveragesFatty acidBrief Research Report030104 developmental biologyEndocrinologyEnzymeLiver metabolismchemistrylipids (amino acids peptides and proteins)Composition (visual arts)fatty acidFrontiers in Physiology
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A case of infective colitis due to Yersinia enterocolitica complicated by microliver abscesses mimicking multiple liver occult metastases: a case rep…

2021

Abstract Background We report an unusual case of infective colitis by Yersinia enterocolitica complicated by microliver abscesses mimicking multiple liver metastases in a 79 yr old female without any risk factors for bacteriaemia by this pathogen. Case presentation The patient was admitted to the Internal Medicine with Stroke Care ward of University Policlinico “P. Giaccone” in Palermo because of the appearance of diarrhoea. After the antimicrobial treatment for infective colitis, the clinicians observed a persistently increased white blood cells (WBC) count and multiple hepatic lesions; after having excluded any neoplastic disease and inflammatory bowel disease (IBD), blood cultures positi…

0301 basic medicinemedicine.medical_specialtySettore MED/09 - Medicina InternaCase report Infective colitis Microliver abscesses Yersinia enterocolitica Aged Anti-Bacterial Agents Bacteremia Liver Neoplasms Treatment Outcome Yersinia Infections Colitis Diagnosis Differential Female Humans Liver AbscessYersinia Infections030106 microbiologyLiver AbscessInfective colitisCase ReportBacteremiaInfectious and parasitic diseasesRC109-216Inflammatory bowel diseaseGastroenterologyMetastasisDiagnosis Differential03 medical and health sciences0302 clinical medicineMedical microbiologyInternal medicinemedicineHumans030212 general & internal medicineYersinia enterocoliticaYersinia enterocoliticaAgedDoxycyclinebiologybusiness.industryLiver NeoplasmsMicroliver abscessesmedicine.diseasebiology.organism_classificationColitisOccultAnti-Bacterial AgentsInfectious DiseasesTreatment OutcomeFemaleDifferential diagnosisbusinessCefiximemedicine.drugBMC Infectious Diseases
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Staphylococcus aureus bloodstream infection in patients with prosthetic joint included in the prospective VIRSTA cohort study: frequency and time of …

2019

International audience; Among 143 patients of the VIRSTA cohort study with Staphylococcus aureus bacteremia and an arthroplasty implanted for more than a year, S. aureus periprosthetic joint infection was observed in 19%. Signs of infection (pain and swelling) were always present, in median 1 day (range, 0-21 days) after onset of bacteremia. Staphylococcus aureus has both a high potential for metastatic infection and a high affinity for foreign material. Possible prosthesis infection is of clinical concern in all patients with preexisting prosthetic materials experiencing S. aureus bloodstream infection (SAB). Prosthetic joints are especially prone to infection during the course of bacterem…

0301 basic medicinemedicine.medical_specialtyStaphylococcus aureusmedicine.medical_treatment030106 microbiologyPeriprostheticbloodstream infectionmedicine.disease_causeProsthesis03 medical and health sciences0302 clinical medicineInternal medicinemedicine030212 general & internal medicineprosthetic joint infectionProspective cohort studybusiness.industryBrief Reportmedicine.diseaseArthroplasty3. Good healthInfectious DiseasesOncologyStaphylococcus aureusBacteremiaImplantbusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyCohort study
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Papilla and pontic area regeneration in patient with gingival smile: A clinical case

2018

Purpose Connective tissue grafts are widely documented as a predictable technique for treating Miller Class I and II recessions, as well as procedures in which soft tissue augmentation is required for aesthetic reasons. This article aims to explore the resolution of a clinical case with this type of problema. Clinical case This case describes a technique for reconstructing a pontic area and adjacent papilla by means of two consecutive connective tissue grafts. The first graft served to increase the amount of tissue in the horizontal direction, and the second promoted vertical reconstruction of the defect. Results and conclusion In cases with aesthetic requirements, restorative intervention …

0301 basic medicinemedicine.medical_specialtybusiness.industryRegeneration (biology)DentistrySoft tissueConnective tissueCase Report030206 dentistryEsthetic Dentistry:CIENCIAS MÉDICAS [UNESCO]Major duodenal papilla03 medical and health sciencesPlastic surgery030104 developmental biology0302 clinical medicinemedicine.anatomical_structureUNESCO::CIENCIAS MÉDICASmedicineIn patientClinical casebusinessRestorative dentistryGeneral DentistryJournal of Clinical and Experimental Dentistry
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A thoracic vertebral localization of a metastasized cutaneous Merkel cell carcinoma: Case report and review of literature

2017

Background: Merkel cell carcinoma (MCC) is a rare neuroendocrine skin tumor, which may be related to sun exposure. It can metastasize to lungs, liver and bone, leading to severe morbidity and mortality. Vertebral metastases from MCC are rare. The authors report the tenth case in the literature, a 59-year-old patient with MCC, which was primarily localized in the scalp, and later provoked distant metastasis to the thoracic spinal column. Case Description: A 59-year-old woman was admitted at our Unit of Neurosurgery with a 4-month history of progressive and severe dorsal back pain, without neurological signs. The patient had been surgically treated for a recidivated MCC in the occipital regio…

0301 basic medicinemedicine.medical_specialtymedicine.medical_treatment03 medical and health sciencesMerkel cell carcinomamedicineAdjuvant therapymedicine.diagnostic_testbusiness.industryMerkel cell carcinomaSettore MED/27 - NeurochirurgiaMagnetic resonance imagingmedicine.diseaseSpinal columnSurgeryRadiation therapySpine: Case ReportDissection030104 developmental biologymedicine.anatomical_structurespinal metastasisScalpSurgeryNeurology (clinical)Neurosurgerybusinessradiofrequency thermoablationSurgical Neurology International
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Bilateral Bifid mandibular canals ? Special relevance for a general dental practitioner. Report of 2 cases

2019

Dental practitioners may encounter bifid mandibular canals upon radiographic assessment, and may not understand the true extent of this presentation. The presentation of a bifid mandibular canal poses difficulties when carrying out dental procedures, including administration of mandibular block anaesthesia, oral surgical procedures of the lower third molars, orthognathic surgery and implant placement. Therefore it is of paramount importance that general dental practitioners be aware of the radiographic appearance, as incorrect diagnosis of this rare presentation can lead to detrimental consequences. The purpose of the communication is to draw dental practitioner’s attention to the variation…

0301 basic medicinemedicine.medical_treatmentRadiographyOrthognathic surgeryDentistryMandibular canalCase ReportOral Surgical Procedures03 medical and health sciences0302 clinical medicinestomatognathic systemmedicineRelevance (law)General Dentistrybusiness.industryDental procedures030206 dentistry:CIENCIAS MÉDICAS [UNESCO]Implant placementstomatognathic diseasesmedicine.anatomical_structureUNESCO::CIENCIAS MÉDICAS030101 anatomy & morphologyPresentation (obstetrics)Oral Surgerybusiness
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Apert Syndrome With FGFR2 758 C > G Mutation: A Chinese Case Report

2018

Background: Apert syndrome is considered as one of the most common craniosynostosis syndromes with a prevalence of 1 in 65,000 individuals, and has a close relationship with point mutations in FGFR2 gene.Case report: Here, we described a Apert syndrome case, who was referred to genetic consultation in our hospital with the symptom of craniosynostosis and syndactyly of the hands and feet. Craniosynostosis, midfacial retrusion, steep wide forehead, larger head circumference, marked depression of the nasal bridge, short and wide nose and proptosis could be found obviously, apart from these, ears were mildly low compared with normal children and there was no cleft lip and palate. Mutation was i…

0301 basic medicinemusculoskeletal diseasesPediatricsmedicine.medical_specialtycongenital hereditary and neonatal diseases and abnormalitiesNasal bridgelcsh:QH426-470Case ReportApert syndromeCraniosynostosis03 medical and health sciencesExonsymbols.namesake0302 clinical medicineGeneticsmedicineSyndactylyGenetics (clinical)NoseSanger sequencingbusiness.industryPoint mutationmedicine.diseaseexons sequencingcraniosynostosislcsh:Genetics030104 developmental biologymedicine.anatomical_structureFGFR2genetic mutationsymbolsMolecular Medicinebusiness030217 neurology & neurosurgeryApert syndromeFrontiers in Genetics
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Cardiotoxicity and Cardioprotection by Artesunate in Larval Zebrafish

2019

Although artesunate (ART) is generally accepted as a safe and well-tolerated first-line treatment of severe malaria, cases of severe side effects and toxicity of this compound are also documented. This study applied larval zebrafishes to determine the acute toxicity and efficacy of ART and performed RNA-sequencing analyses to unravel the underlying signaling pathways contributing to ART’s activities. Results from acute toxicity assay showed that a single-dose intravenous injection of ART from 3.6 ng/fish (1/9 maximum nonlethal concentration) to 41.8 ng/fish (lethal dose 10%) obviously induced pericardial edema, circulation defects, yolk sac absorption delay, renal edema, and swim bladder l…

0301 basic medicinenatural productsHealth Toxicology and MutagenesisShort ReportmalariaDevelopmental toxicityPharmacologyToxicologyNephrotoxicity03 medical and health scienceschemistry.chemical_compound0302 clinical medicineEdemamedicinecancernetwork pharmacologyCardiotoxicityChemical Health and Safetybusiness.industrylcsh:RM1-950Public Health Environmental and Occupational Healthmedicine.diseaseAcute toxicity030104 developmental biologylcsh:Therapeutics. PharmacologychemistryArtesunate030220 oncology & carcinogenesisHeart failureToxicitymedicine.symptombusinessDose-Response
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A comprehensive approach to assigning periodontal prognosis

2018

Abstract Aim The purpose of this retrospective case series study was to evaluate the usefulness and performance of a comprehensive approach to assigning periodontal prognosis by assessing the risk of tooth loss due to periodontal disease (TLPD) and estimate the survival time (ST) of periodontally compromised teeth (PCT). Material and Methods The Long‐Term Outcome (LTO) index was utilized to assess the risk of TLPD, at baseline, in 100 patients following periodontal maintenance for a mean 24.7 year (±2.4). A TLPD prediction model was utilized to assign ST to PCT. The performance of the TLPD prediction based on both parameters was assessed. Results The mean TLPD rate increased as the LTO inde…

0301 basic medicineperiodontal prognosismedicine.medical_specialtybusiness.industryperiodontal diseaseCase Report or Case Series030206 dentistryLower riskPeriodontal Therapy03 medical and health sciences030104 developmental biology0302 clinical medicinePeriodontal diseasetooth lossInternal medicineTooth lossmedicinePeriodonticsIn patientmedicine.symptombusinessPeriodontal maintenanceCase seriesJournal of Clinical Periodontology
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