Search results for "EPOR"
showing 10 items of 2839 documents
A Diagnostic-Oriented Screening Scale for Anxiety Disorders: The Center for Epidemiologic Studies Anxiety Scale (CESA)
2020
Objectives This paper introduces a new diagnostically oriented screening scale for anxiety disorders, the Center for Epidemiologic Studies Anxiety scale (CESA), designed in parallel to the revised Center for Epidemiologic Studies Depression scale (CESD-R). In this study, the CESA was used as a diagnostic screening tool for detecting the presence of anxiety disorder symptomatology ascertained by a clinical psychiatric evaluation based on the DSM-5 criteria. The CESA is designed to provide an overall evaluation of anxiety as well as to screen for four important anxiety disorders (agoraphobia, social phobia, blood-illness phobia, and panic disorder). Methods The test sample was composed of 80 …
Psychosocial Factors and Chronic Illness as Predictors for Anxiety and Depression in Adolescence
2020
Adolescence is a challenging time when emotional difficulties often arise. Self-esteem, good relationships with peers, and emotional competences can buffer the effects of these difficulties. The difficulties can be even greater when coupled with the presence of a chronic physical illness (CD). Our goal is to analyze psychosocial factors and CD as predictors for anxiety and depression. It was compared the results of structural equation models (SEM) with models based on qualitative comparative analysis (QCA) to analyze the possible influence of these variables on levels of anxiety-depression in adolescents with and without CD. The sample consisted of 681 adolescents, between 12 and 16 years o…
Clima motivacional percibido, motivación autodeterminada y autoestima en jóvenes deportistas mexicanos
2010
En el marco de la Teoría de las Metas de Logro (Ames, 1992; Dweck, 1999; Nicholls, 1989), y de la Teoría de la Autodeterminación (Deci y Ryan, 1985, 2000) en el presente trabajo se puso a prueba un modelo con la siguiente secuencia: Clima motivacional percibido (clima de implicación en la tarea y clima de implicación en el ego) ÞMotivación Autodeterminada Þ Autoestima. Además, se analizó si la motivación autodeterminada actuaba como mediadora entre cada una de las dos dimensiones del clima motivacional percibido (clima de implicación en la tarea y clima de implicación en el ego) y la autoestima. Participaron 651 deportistas juveniles mexicanos (Medad = 13,99; DT = 1,88), 330 chicas y 321 ch…
A classical phenotype of Anderson-Fabry disease in a female patient with intronic mutations of the GLA gene: a case report
2012
Abstract Background Fabry disease (FD) is a hereditary metabolic disorder caused by the partial or total inactivation of a lysosomal hydrolase, the enzyme α-galactosidase A (GLA). This inactivation is responsible for the storage of undegraded glycosphingolipids in the lysosomes with subsequent cellular and microvascular dysfunction. The incidence of disease is estimated at 1:40,000 in the general population, although neonatal screening initiatives have found an unexpectedly high prevalence of genetic alterations, up to 1:3,100, in newborns in Italy, and have identified a surprisingly high frequency of newborn males with genetic alterations (about 1:1,500) in Taiwan. Case presentation We des…
December 13–14, 2007 in Mainz: Workshop on “Language contact in Ethiopia: Examples from Cushitic, Omotic and Semitic languages”
2012
Conference Review
April 27–30, 2005 in Addis Ababa: Stemming the Tide: Efforts at Preserving Languages
2012
Conference Review
Pinpointing the PRDM9-PRDM7 Gene Duplication Event During Primate Divergence
2021
Studies on the function of PRDM9 in model systems and its evolution during vertebrate divergence shed light on the basic molecular mechanisms of hybrid sterility and its evolutionary consequences. However, information regarding PRDM9-homolog, PRDM7, whose origin is placed in the primate evolutionary tree, as well as information about the fast-evolving DNA-binding zinc finger array of strepsirrhine PRDM9 are scarce. Thus, we aimed to narrow down the date of the duplication event leading to the emergence of PRDM7 during primate evolution by comparing the phylogenetic tree reconstructions of representative primate samples of PRDM orthologs and paralogs. To confirm our PRDM7 paralogization patt…
EL FÚTBOL COMO POTENCIADOR DE TURISMO DEPORTIVO
2018
El turismo deportivo se puede definir como un viaje de ocio con el fin de participar, de distintas formas, en actividades físico-deportivas. Respecto al fútbol, sus encuentros constituyen grandes eventos deportivos, atracciones donde el turista vivencia, principalmente de forma pasiva, distintas actividades, ya sea como espectador o como visitante de las atracciones turístico-futbolísticas. Sin duda, el fútbol tiene un importante valor turístico, en especial para la estructura turística local, incidiendo de manera directa en aspectos como la promoción y difusión de un destino turístico. En este marco, los clubs de fútbol se convierten en promotores turísticos de su ciudad, además de desarro…
Responsiveness to anti-PD-1 and anti-CTLA-4 immune checkpoint blockade in SB28 and GL261 mouse glioma models.
2018
Immune checkpoint blockade (ICB) is currently evaluated in patients with glioblastoma (GBM), based on encouraging clinical data in other cancers, and results from studies with the methylcholanthrene-induced GL261 mouse glioma. In this paper, we describe a novel model faithfully recapitulating some key human GBM characteristics, including low mutational load, a factor reported as a prognostic indicator of ICB response. Consistent with this observation, SB28 is completely resistant to ICB, contrasting with treatment sensitivity of the more highly mutated GL261. Moreover, SB28 shows features of a poorly immunogenic tumor, with low MHC-I expression and modest CD8(+) T-cell infiltration, suggest…
Mung Bean nuclease mapping of RNAs 3' end
2009
Abstract A method is described that allows an accurate mapping of 3' ends of RNAs. In this method a labeled DNA probe, containing the presumed 3' end of the RNA under analysis is allowed to anneals to the RNA itself. Mung-bean nuclease is then used to digest single strands of both RNA and DNA. Electrophoretic fractionation of "protected" undigested, labeled DNA is than performed using a sequence reaction of a known DNA as length marker. This procedure was applied to the analysis of both a polyA RNA (Interleukin 10 mRNA) and non polyA RNAs (sea urchin 18S and 26S rRNAs). This method might be potentially relevant for the evaluation of the role of posttrascriptional control of IL-10 in the pat…