Search results for "EPOR"
showing 10 items of 2839 documents
Glucose Metabolism in Children With Growth Hormone Deficiency
2018
Background: The growth hormone (GH)/insulin-like growth factor 1 (IGF-1) axis has a fundamental impact on glucose metabolism. Therefore, both untreated GH deficiency (GHD) and GH treatment (GHT) may be associated with some metabolic alterations, although the abnormalities of glucose metabolism have been investigated by relatively few studies as main outcomes. Aim: The present review summarizes the available data on glucose metabolism in children with GHD, providing an overview of the current state of the art in order better to clarify the real metabolic impact of GHD and GHT. Methods: Among all the existing studies, we evaluated all original studies that fulfilled our criteria for analysis …
Dual lumen microcatheters for recanalisation of chronic total occlusions: A EuroCTO Club expert panel report
2021
Dual lumen microcatheters (DLMC) have become indispensable tools in the setting of percutaneous coronary intervention (PCI) of chronic total occlusion (CTO). Other than allowing preservation and treatment of bifurcated coronary branches within or in the proximity of the CTO-body, they enable the use of modified parallel wiring, antegrade dissection and re-entry, collateral selection and retrograde negotiation of the distal CTO-cap. This Euro-CTO consensus document describes current DLMCs and suggests a practical guide to anatomies and techniques in which these devices are applicable.
Health-related Quality of Life in Nonalcoholic Fatty Liver Disease Associates With Hepatic Inflammation
2019
Background & Aims Chronic liver disease has negative effects on health-related quality of life (HRQL). We analyzed data from the European non-alcoholic fatty liver disease (NAFLD) registry to assess the effects of NAFLD on HRQL. Methods We collected data from 304 patients (mean age, 52.3 ± 12.9 years) with histologically defined NAFLD enrolled prospectively into the European NAFLD Registry in Germany, the United Kingdom, and Spain. The chronic liver disease questionnaire (CLDQ) was completed within 6 months of liver biopsy collection. Results The mean CLDQ overall score was 5.0 ± 1.2, with the lowest score in the category fatigue (4.3 ± 1.6) and the highest scores for activity (5.4 ± 1.4). …
Facial nerve schwannoma involving middle cranial fossa: When the unilateral sensorineural hearing loss guide to the correct diagnosis
2011
The Facial Nerve Schwannoma is a rare tumor and it seldom involved the middle cranial fossa. Facial nerve schwannoma has various manifestations, including facial palsy but unfortunately facial nerve is very resistant to compression and often facial nerve paralysis or a facial weakness are not present. We present a case of giant facial nerve schwannoma involved the middle cranial fossa without facial nerve paralysis. In these cases the unilateral hearing loss (if present) guide to a correct diagnosis.
Local Sleep Slow-Wave Activity Colocalizes With the Ictal Symptomatogenic Zone in a Patient With Reflex Epilepsy
2020
Background: Slow-wave activity (SWA) during non-rapid eye movement (NREM) sleep reflects synaptic potentiation during preceding wakefulness. Epileptic activity may induce increases in state-dependent SWA in human brains, therefore, localization of SWA may prove useful in the presurgical workup of epileptic patients. We analyzed high-density electroencephalography (HDEEG) data across vigilance states from a reflex epilepsy patient with a clearly localizable ictal symptomatogenic zone to provide a proof-of-concept for the testability of this hypothesis. Methods: Overnight HDEEG recordings were obtained in the patient during REM sleep, NREM sleep, wakefulness, and during a right facial motor s…
Padel: A quantitative study of the shots and movements in the high-performance
2013
Padel is a sport that has increasing its importance in recent years. Despite this evolution, there is a lack of scientific papers analyzing padel aspects, specifically about the quantification of movements and shots during match. The purpose of this study was to perform quantitative analyses of movements and shots in padel in order to establish the importance of each type. Twenty male professional players were recorded with a video during ten matches and movements (lateral, head-on and backward displacement, split-steps, jump for a smash, and turns pivoting on the right or left foot) and shots (direct and indirect drive, backhand, smash and lob, and direct volley) were identified, quantifie…
Cone beam computed tomography diagnostic imaging of intra-osseous mucoepidermoid carcinoma in the mandible
2017
Intra-osseous mucoepidermoid carcinoma in the mandible is a rarely reported entity, comprising only 2-3% of all mucoepidermoid carcinomas. Unilocular and/or multilocular radiolucency is characteristic of mucoepidermoid carcinoma, but has a radiographic appearance similar to that of odontogenic benign and malignant tumors and thus cannot be accurately diagnosed on plain films. This article describes a case of a 36-year-old man with intra-osseous mucoepidermoid carcinoma in the left mandible. For a detailed analysis, both panoramic radiograph and cone beam computed tomograph were taken. Important clinico-pathological and imaging features, differential diagnosis and review of the literature ar…
Waste not, want not: Report of a completely calcified C1-C2 juxtafacet cyst and literature review
2021
Background: Calcified juxtafacet cysts in the cervical spine are extremely rate. Such symptomatic cysts commonly cause neck pain, radiculopathy, or even myelopathy. MR and CT studies typically document cord/ root compression. On occasion, some of these cysts will spontaneously regress, while many others may warrant surgical removal. Case Description: A 70-year-old male presented with a 2-year history of a progressive tetraparesis. The preoperative MR/CT studies showed a C1-C2 left extradural mass occupying more than half of the spinal canal. On MR, it was homogeneously hypointense on both T1- and T2-weighted images, while the CT showed a calcified cyst. Intraoperative and histopathological…
Hirayama disease – Early MRI diagnosis of subacute medullary ischemia: A case report
2020
Background: Hirayama disease (HD) is a rare, benign, and self-limiting motor neuron disorder that results in selective motor impairment of the C7-T1 myotomes. It is characterized by progressive, unilateral, or bilateral asymmetric muscle atrophy of the distal upper extremities and myelopathy. Case Description: A 23-year-old male presented with bilateral atrophy of the thenar/hypothenar eminences/ interosseous muscles, plus left-hand weakness. The cervical MRI documented subacute ischemic damage of the distal cervical cord. To rule out a tumor and reduce questionable cord compression, the patient underwent a C5–C6 anterior cervical discectomy and fusion (ACDF) immediately followed by a lami…
The STROCSS statement: Strengthening the Reporting of Cohort Studies in Surgery
2017
Abstract Introduction The development of reporting guidelines over the past 20 years represents a major advance in scholarly publishing with recent evidence showing positive impacts. Whilst over 350 reporting guidelines exist, there are few that are specific to surgery. Here we describe the development of the STROCSS guideline ( St rengthening the R eporting o f C ohort S tudies in S urgery). Methods and analysis We published our protocol apriori . Current guidelines for case series (PROCESS), cohort studies (STROBE) and randomised controlled trials (CONSORT) were analysed to compile a list of items which were used as baseline material for developing a suitable checklist for surgical cohort…