Search results for "EPSPS"

showing 8 items of 8 documents

Scientific opinion on an application by Dow AgroSciences LLC (EFSA-GMO-NL-2012-106) for the placing on the market of genetically modified herbicide-t…

2017

Abstract Soybean DAS‐44406‐6 expresses 5‐enolpyruvyl‐shikimate‐3‐phosphate synthase (2mEPSPS), conferring tolerance to glyphosate‐based herbicides, aryloxyalkanoate dioxygenase (AAD‐12), conferring tolerance to 2,4‐dichlorophenoxyacetic acid (2,4‐D) and other related phenoxy herbicides, and phosphinothricin acetyl transferase (PAT), conferring tolerance to glufosinate ammonium‐based herbicides. The molecular characterisation data and bioinformatics analyses did not identify issues requiring assessment for food/feed safety. The agronomic and phenotypic characteristics revealed no relevant differences between soybean DAS‐44406‐6 and its conventional counterpart, except for pod count, seed cou…

herbicide toleranceVeterinary (miscellaneous)Plant ScienceTP1-1185010501 environmental sciences01 natural sciencesMicrobiology0404 agricultural biotechnologyRegulation 1829/2003TX341-6410105 earth and related environmental sciencesNutrition. Foods and food supplyChemical technologyfungifood and beverages04 agricultural and veterinary sciencesDAS‐44406‐6040401 food sciencesoybean (Glycine max cv. Maverick)Scientific OpinionSettore AGR/11 - Entomologia Generale E ApplicataAnimal Science and ZoologyParasitologyAAD‐122mEPSPSPATFood Science2mEPSPS; AAD‐12; DAS‐44406‐6; PAT; Regulation 1829/2003; herbicide tolerance; soybean (Glycine max cv. Maverick)
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Assessment of genetically modified cotton GHB614 × LLCotton25 × MON 15985 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFS…

2018

The three-event stack cotton GHB614 x LLCotton25 x MON 15985 was produced by conventional crossing to combine three single cotton events, GHB614, LLCotton25 and MON 15985. The EFSA GMO Panel previously assessed the three single events and did not identify safety concerns. No new data on the single events that could lead to modification of the original conclusions on their safety were identified. Based on the molecular, agronomic, phenotypic and compositional characteristics, the combination of the single events and of the newly expressed proteins in the three-event stack cotton did not give rise to food and feed safety or nutritional issues. Food and feed derived from cotton GHB614 x LLCott…

0106 biological sciences0301 basic medicineVeterinary (miscellaneous)[SDV]Life Sciences [q-bio]Plant ScienceTP1-1185Biology01 natural sciencesMicrobiology03 medical and health sciencesEnvironmental safetyNPTIIGUSCry1AcTX341-641cotton GHB614 × LLCotton25 × MON 15985Cry2Ab2cotton GHB614 x LLCotton25 x MON 159852. Zero hungerAnimal healthbusiness.industryNutrition. Foods and food supplyGMOChemical technologyRegulation (EC) 1829/2003Food safetyGenetically modified organismBiotechnologySettore AGR/02 - Agronomia E Coltivazioni ErbaceeScientific Opinion030104 developmental biologySettore AGR/11 - Entomologia Generale E ApplicataAnimal Science and ZoologyParasitologyGMO; cotton GHB614 x LLCotton25 x MON 15985; Regulation (EC) 1829/2003; Cry1Ac; Cry2Ab2; GUS; NPTII; 2mEPSPS; PATbusiness2mEPSPSPAT010606 plant biology & botanyFood Science
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Glyphosate-based herbicide use affects individual microbial taxa in strawberry endosphere but not the microbial community composition

2023

AbstractAimsIn a field study, the effects of treatments of glyphosate-based herbicides (GBHs) in soil, alone and in combination with phosphate fertilizer, were examined on the performance and endophytic microbiota of garden strawberry.Methods and resultsThe root and leaf endophytic microbiota of garden strawberries grown in GBH-treated and untreated soil, with and without phosphate fertilizer, were analyzed. Next, bioinformatics analysis on the type of 5-enolpyruvylshikimate-3-phosphate synthase enzyme was conducted to assess the potential sensitivity of strawberry-associated bacteria and fungi to glyphosate, and to compare the results with field observations. GBH treatments altered the abu…

endofyytitEPSPSplant performancefosforilannoitteetroundupGeneral Medicineherbisiditphosphate fertilizerApplied Microbiology and BiotechnologyFragaria X ananassamikrobistoherbicidemicrobiotaendophyteBiotechnology
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A novel arousal-based individual screening reveals susceptibility and resilience to PTSD-like phenotypes in mice

2021

Translational animal models for studying post-traumatic stress disorder (PTSD) are valuable for elucidating the poorly understood neurobiology of this neuropsychiatric disorder. These models should encompass crucial features, including persistence of PTSD-like phenotypes triggered after exposure to a single traumatic event, trauma susceptibility/resilience and predictive validity. Here we propose a novel arousal-based individual screening (AIS) model that recapitulates all these features. The AIS model was designed by coupling the traumatization (24 h restraint) of C57BL/6 J mice with a novel individual screening. This screening consists of z-normalization of post-trauma changes in startle …

Physiology5-trial SM 5-trial social memoryBiochemistryFight-or-flight responseFST forced swim test0302 clinical medicineEndocrinologySSRIs selective serotonin reuptake inhibitorsDSM-5 Diagnostic and Statistical Manual of Mental DisordersOriginal Research ArticleFear conditioningmedia_commonHT hypothalamusAIS arousal-based individual screeningQP351-495ParoxetinePhenotypeHPA hypothalamic–pituitary–adrenalBST basal synaptic transmissionHIP hippocampusPTSD post-traumatic stress disorder[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]Psychological resilienceAmy amygdalaRC321-571medicine.drugNeurophysiology and neuropsychologymedia_common.quotation_subjectBDNF brain derived neurotropic factorFear conditioningNeurosciences. Biological psychiatry. NeuropsychiatryBiologyStressArousal03 medical and health sciencesCellular and Molecular NeuroscienceAnimal model Fear conditioning Resilience Stress Susceptibility Z-scoreAnimal modelCORT corticosteroneOF open fieldTE trauma-exposedBiological neural networkmedicineAnimal model[SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]C controlfEPSPs field excitatory post-synaptic potentialsSGK1 serum/glucocorticoid-regulated kinase 1RC346-429Molecular BiologyResilienceEndocrine and Autonomic SystemsZ-scoremPFC medial prefrontal cortexFKBP5 FK506 binding protein 5FDA Food and Drug AdministrationASR acoustic startle reactivityEPM elevated plus maze030227 psychiatrySusceptibilityAnimal model; Fear conditioning; Resilience; Stress; Susceptibility; Z-scoreNeurology. Diseases of the nervous systemNeuroscience030217 neurology & neurosurgeryNeurobiology of Stress
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Assessment of genetically modified sugar beet H7‐1 for renewal of authorisation under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐RX‐006)

2017

Efsa Panel On Genetically Modified Organisms (gmo)Scientific opinionRequestor: European Commission (DG SANTE)Question number: EFSA-Q-2017-00026; Following the submission of application EFSA-GMO-RX-006 under Regulation (EC) No 1829/2003 fromKWS SAAT SE and Monsanto Company, the Panel on Genetically Modified Organisms of the EuropeanFood Safety Authority (GMO Panel) was asked to deliver a scientific risk assessment on the datasubmitted in the context of the renewal of authorisation application for the herbicide-tolerantgenetically modified sugar beet H7-1. The data received in the context of this renewal applicationcontained a systematic search and evaluation of literature, updated bioinforma…

040301 veterinary sciencesVeterinary (miscellaneous)gmo[SDV]Life Sciences [q-bio]sugarbeetogmPlant Science010501 environmental sciencessugar beet;H7-1;renewal;articles 11 and 23;regulation (EC) No 1829/2003;CP4 EPSPS01 natural sciencesMicrobiology0403 veterinary sciencearticles 11 and 230105 earth and related environmental sciencesrenewalCP4 EPSPSfungiregulation (EC) No 1829/200304 agricultural and veterinary sciencessugar beet10079 Institute of Veterinary Pharmacology and Toxicologybetterave sucrièreH7‐1H7-1Scientific Opinion570 Life sciences; biologyAnimal Science and ZoologyParasitologyregulation (EC) No 1829/2003Food Science
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Assessment of genetically modified cotton GHB614 × T304‐40 × GHB119 for food and feed uses, import and processing under Regulation (EC) No 1829/2003 …

2018

International audience; The three-event stack cotton GHB614 x T304-40 x GHB119 was produced by conventional crossing to combine three single events, GHB614, T304-40 and GHB119. The genetically modified organisms (GMO) Panel previously assessed the three single cotton events and did not identify safety concerns. No new data on the single cotton events that could lead to modification of the original conclusions on their safety were identified. Based on the molecular, agronomic, phenotypic and compositional characteristics, the combination of the single cotton events and of the newly expressed proteins in the three-event stack cotton did not give rise to food and feed safety concern. The GMO P…

Veterinary (miscellaneous)[SDV]Life Sciences [q-bio]2405 ParasitologyPlant Science010501 environmental sciencesBiology01 natural sciencesMicrobiology[SHS]Humanities and Social Sciences1110 Plant Science[SDV.IDA]Life Sciences [q-bio]/Food engineering[SDV.BV]Life Sciences [q-bio]/Vegetal Biology[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process EngineeringCry1Ab1106 Food Science0105 earth and related environmental sciencesCry2Ae2. Zero hungerbusiness.industryGMO2404 MicrobiologyRegulation (EC) 1829/200304 agricultural and veterinary sciences10079 Institute of Veterinary Pharmacology and ToxicologyGenetically modified organismBiotechnology3401 Veterinary (miscellaneous)Scientific Opinion[SDE]Environmental Sciences040103 agronomy & agriculture0401 agriculture forestry and fisheries570 Life sciences; biologyAnimal Science and ZoologyParasitologycotton GHB614 x T304-40 x GHB1191103 Animal Science and Zoologybusiness2mEPSPSPATFood Science
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Scientific Opinion on application EFSA‐GMO‐BE‐2013‐117 for authorisation of genetically modified maize MON 87427 × MON 89034 × NK603 and subcombinati…

2017

Scientific opinionRequestor: Competent Authority of BelgiumQuestion number: EFSA-Q-2013-00765; In this opinion, the EFSA Panel on Genetically Modified Organisms (GMO Panel) assessed the three-event stack maize MON 87427 9 MON 89034 9 NK603 and its three subcombinations, independently of their origin. The GMO Panel has previously assessed the three single events combined to produce this three-event stack maize and did not identify safety concerns. No new data on the single events, leading to modification of the original conclusions on their safety, were identified. Based on the molecular, agronomic, phenotypic and compositional characteristics, the combination of the single maize events and …

0106 biological sciencesCry1Aherbicide tolerancemaïsVeterinary (miscellaneous)gmo[SDV]Life Sciences [q-bio]MON87427xMON89034xNK603ogmPlant Science010501 environmental sciencesmaizeCP4EPSPS01 natural sciencesMicrobiologyzea maysMON 87427 × MON 89034 × NK603Cry2Ab2CP4 EPSPS0105 earth and related environmental sciences2. Zero hungerCP4 EPSPSCry1A.105indian cornRegulation (EC) No 1829/2003105GMO;maize;herbicide tolerance;insect resistance;CP4 EPSPS;Cry1A.105;Cry2Ab2;Regulation (EC) No 1829/2003;MON 87427 x MON 89034 x NK603MON 87427 9 MON 89034 9 NK603Scientific OpinionRegulation (EC) No1829/2003Animal Science and ZoologyParasitologyinsect resistance010606 plant biology & botanyFood ScienceRegulation (EC) No 1829/2003
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Assessment of genetically modified maize MON 87411 for food and feed uses, import and processing, under Regulation (EC) No 1829/2003 (application EFS…

2018

Maize MON 87411 was developed to confer resistance to corn rootworms (Diabrotica spp.) by the expression of a modified version of the Bacillus thuringiensis cry3Bb1 gene and a DvSnf7 dsRNA expression cassette, and tolerance to glyphosate-containing herbicides by the expression of a CP4 5-enolpyruvylshikimate-3-phosphate synthase (cp4 epsps) gene. The molecular characterisation data and bioinformatics analyses did not identify issues requiring assessment for food and feed safety. No statistically significant differences in the agronomic and phenotypic characteristics tested between maize MON 87411 and its conventional counterpart were identified. The compositional analysis of maize MON 87411…

0301 basic medicineCry3Bb1DvSnf7Cry3Bb1Veterinary (miscellaneous)[SDV]Life Sciences [q-bio]TP1-1185Plant Science010501 environmental sciences01 natural sciencesMicrobiology03 medical and health sciencesPlant scienceEnvironmental safetyBacillus thuringiensisTX341-641Diabroticamaize (Zea mays)0105 earth and related environmental sciences2. Zero hungerGenetically modified maizeCP4 EPSPSbiologyAnimal healthNutrition. Foods and food supplybusiness.industryGMOChemical technologyRegulation (EC) No 1829/2003biology.organism_classificationFood safetyMON 87411BiotechnologyScientific Opinion030104 developmental biologyAnimal Science and ZoologyParasitologybusinessRegulation (EC) No 1829/2003Food Science
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