Search results for "ERAN"
showing 10 items of 1784 documents
Contributo allo studio del giudizio di ottemperanza nel processo tributario
2008
Il lavoro analizza l'istituto dell'ottemperanza in materia tributaria, esaminando profili procedurali e e applicativi. Si esamina la natura giuridica del giudizio di ottemperanza, l'esecutività delle sentenze delle commissioni tributarie,la caratterizzazione del giudizio di ottemperanza nel processo tributario.
Estudio médico-legal de los casos de asesinatos en serie sucedidos en España en los últimos treinta años (1984-2014)
2018
El asesino en serie es visto hoy en día como uno de los grandes depredadores humanos de nuestra sociedad. Constituye un problema y un gran reto para aquellos que se enfrentan a este tipo de violencia, tanto al tratar de atajarla como de prevenirla. Como en cualquier otro tipo de delito, conocer y comprender su génesis, sus motivaciones y los factores que lo integran es trascendental para abordar el problema. España no es ajena a este tipo de violencia. No son pocos los homicidas que han presentado tal clase de patrón en los últimos años. El presente trabajo trata de analizar los casos de asesinatos seriales que se han dado en nuestro país en las tres últimas décadas, entre 1984 y 2014, una …
Identification of the privileged position in the imidazo[1,2-a]pyridine ring of phosphonocarboxylates for development of Rab geranylgeranyl transfera…
2017
Members of the Rab GTPase family are master regulators of vesicle trafficking. When disregulated, they are associated with a number of pathological states. The inhibition of RGGT, an enzyme responsible for post-translational geranylgeranylation of Rab GTPases represents one way to control the activity of these proteins. Because the number of molecules modulating RGGT is limited, we combined molecular modeling with biological assays to ascertain how modifications of phosphonocarboxylates, the first reported RGGT inhibitors, rationally improve understanding of their structure–activity relationship. We have identified the privileged position in the core scaffold of the imidazo[1,2-a]pyridine r…
IAEA Contribution to Nanosized Targeted Radiopharmaceuticals for Drug Delivery.
2022
The rapidly growing interest in the application of nanoscience in the future design of radiopharmaceuticals and the development of nanosized radiopharmaceuticals in the late 2000′s, resulted in the creation of a Coordinated Research Project (CRP) by the International Atomic Energy Agency (IAEA) in 2014. This CRP entitled ‘Nanosized delivery systems for radiopharmaceuticals’ involved a team of expert scientist from various member states. This team of scientists worked on a number of cutting-edge areas of nanoscience with a focus on developing well-defined, highly effective and site-specific delivery systems of radiopharmaceuticals. Specifically, focus areas of various teams of scientists com…
Determinants of the interannual relationships between remote sensed photosynthetic activity and rainfall in tropical Africa
2007
International audience; The response of photosynthetic activity to interannual rainfall variations in Africa South of the Sahara is examined using 20 years (1981-2000) of Normalised Difference Vegetation Index (NDVI) AVHRR data. Linear correlations and regressions were computed between annual NDVI and annual rainfall at a 0.5° latitude/longitude resolution, based on two gridded precipitation datasets (Climate Prediction Center Merged Analysis of Precipitation [CMAP] and Climatic Research Unit [CRU]). The spatial patterns were then examined to detect how they relate to the mean annual rainfall amounts, land-cover types as from the Global Land Cover 2000 data set, soil properties and soil typ…
Kuormituskoe modernin kuvantamisen aikakaudella
2019
Kuormituskoetta käytetään sepelvaltimotaudin ja muidenkin sydänsairauksien diagnosoinnissa, ennusteen arvioinnissa, hoidon suunnittelussa ja seurannassa. Kuormituskokeen keskeisin etu on sen helppo saatavuus sekä avoterveydenhuollossa että erikoissairaanhoidossa. Rasitukseen liittyvien oireiden tai suorituskyvyn heikkenemisen yhteydessä kuormituskoe on edelleen arvokas perustutkimus. Sen käytön keskeisin rajoite liittyy sen diagnostiseen osuvuuteen, ja sepelvaltimotaudin ali- ja ylidiagnostiikan välttämiseksi kuormituskokeen käyttö tulisikin rajata liikuntakykyisiin potilaisiin, joilla taudin todennäköisyys ennen testiä on keskisuuri tai suuri. Kuormituskoe sopii potilaille, joiden lepo-EKG…
Adaptation to fluctuations in temperature by nine species of bacteria.
2017
Abstract Rapid environmental fluctuations are ubiquitous in the wild, yet majority of experimental studies mostly consider effects of slow fluctuations on organism. To test the evolutionary consequences of fast fluctuations, we conducted nine independent experimental evolution experiments with bacteria. Experimental conditions were same for all species, and we allowed them to evolve either in fluctuating temperature alternating rapidly between 20°C and 40°C or at constant 30°C temperature. After experimental evolution, we tested the performance of the clones in both rapid fluctuation and in constant environments (20°C, 30°C and 40°C). Results from experiments on these nine species were comb…
Measuring phenotypes in fluctuating environments
2020
Despite considerable theoretical interest in how the evolution of phenotypic plasticity should be shaped by environmental variability and stochasticity, how individuals actually respond to these aspects of the environment within their own lifetimes remains unclear. We propose that this understanding has been hampered by experimental approaches that expose organisms to fluctuating environments (typically treatments where fluctuations in the environment are cyclical vs. erratic) for a pre‐determined duration, while ensuring that the mean environment over that the entire exposure period is invariable. This approach implicitly assumes that responses to the mean and variance/predictability in th…
Acclimation capacity and rate change through life in the zooplankton Daphnia
2020
When a change in the environment occurs, organisms can maintain an optimal phenotypic state via plastic, reversible changes to their phenotypes. These adjustments, when occurring within a generation, are described as the process of acclimation. While acclimation has been studied for more than half a century, global environmental change has stimulated renewed interest in quantifying variation in the rate and capacity with which this process occurs, particularly among ectothermic organisms. Yet, despite the likely ecological importance of acclimation capacity and rate, how these traits change throughout life among members of the same species is largely unstudied. Here we investigate these rel…
El concepto de nación en el constitucionalismo decimonónico español
2017
En este estudio se analiza el concepto de nación española por medio de los textos constitucionales decimonónicos y los debates que se desarrollaron entorno a su redacción en las sesiones plenarias de las Cortes. De este modo, se pretende arrojar luz sobre la comprensión del concepto de nación como idea no sólo metajurídica sino también jurídica. En esta tesis doctoral se examina la idea de nación desde una triple vertiente jurídica, convinando la Historia del Derecho, el Derecho Constitucional y la Filosofía del Derecho. De este modo, desde una perspectiva puramente jurídica, la nación se dilucida como un constructo surgido de la voluntad política, que a su vez se asienta y legitima mediant…