Search results for "ERAS"
showing 10 items of 4431 documents
La Pequeña Edad de Hielo en el Golfo de València. Procesos en deltas y sistemas de restinga-albufera. La desestabilización reciente
2023
En este proyecto de Tesis, se ha pretendido caracterizar formas, procesos y dinámica de sistemas de delta-laguna-barrera a escala de tiempo histórica relacionados con el episodio climático histórico de la Pequeña Edad de Hielo (PEH, siglos XIV-XIX) en el Golfo de València. Finalmente, también se aborda el análisis de la desestabilización de estos sistemas ante la acción antrópica y el Calentamiento Global. Los deltas, las barreras (o restingas) y los humedales (o albuferas) mediterráneos constituyen ambientes altamente sensibles a los cambios tanto de origen natural como antrópico. La franja costera del Golfo de València, formada por un conjunto prácticamente ininterrumpido de sistemas de d…
Leishmania tarentolae and Leishmania infantum in humans, dogs and cats in the Pelagie archipelago, southern Italy.
2021
Visceral leishmaniasis (VL) caused by Leishmania infantum is endemic in the Mediterranean basin with most of the infected human patients remaining asymptomatic. Recently, the saurian-associated Leishmania tarentolae was detected in human blood donors and in sheltered dogs. The circulation of L. infantum and L. tarentolae was investigated in humans, dogs and cats living in the Pelagie islands (Sicily, Italy) by multiple serological and molecular testing. Human serum samples (n = 346) were tested to assess the exposure to L. infantum by immunofluorescence antibody test (IFAT), enzyme-linked immunosorbent assay (ELISA) and Western blot (WB) and to L. tarentolae by IFAT. Meanwhile, sera from do…
Investigation and control of a Norovirus outbreak of probable waterborne transmission through a municipal groundwater system
2014
During March 2011 an outbreak of gastroenteritis occurred in Santo Stefano di Quisquina, Agrigento, Sicily, Italy. Within two weeks 156 cases were identified among the 4,965 people living in the municipality. An epidemiological investigation was conducted to characterize the outbreak and target the control measures. A case was defined as a person developing diarrhea or vomiting during February 27–March 13, 2011. Stool specimens were collected from 12 cases. Norovirus (NoV) genotype GII.4 variant New Orleans 2009 was identified in stool samples from 11 of 12 cases tested (91.7%). Epidemiological investigations suggested a possible association with municipal drinking water consumption. Water …
Angļu valodas skolotāju uzskati par skolotāja darbu un karjeru
2019
Maģistra darba mērķis ir izpētīt angļu valodas skolotāju priekšstatus par skolotāja darbu un karjeru, lai veicinātu izpratni par angļu valodas skolotāju karjeras attīstību. Maģistra darba aktualitāti nosaka tas, ka Latvijas skolās trūkst angļu valodas skolotāju. Daudzi angļu valodas skolotāji izvēlas sekot dažādiem karjeras ceļiem. Tika konstatēta nepieciešamība izpētīt faktorus, kas nosaka viņu karjeras izvēli, lai skaidrotu angļu valodas skolotāju trūkumu skolās. Naratīvais pētījums ir izvēlēts kā pētījuma metode, lai, atstāstot stāstus, izzinātu praktizējošo un nepraktizējošo skolotāju dzīves pieredzi un sniegtu ieskatu angļu valodas skolotāju izpratnē par skolotāja darbu un karjeru. Dat…
Exploring the conditions of English language education through the experience of Eritrean Sophomore English language learners and teachers
2023
This study addresses the little studied context of English language education in Eritrea. Despite the teaching of English as a subject and the forward-looking mother tongue policy implemented in Eritrean elementary education, Eritrean students struggle to cope with English as the medium of instruction from the start of junior school to the end of tertiary education. This qualitative study analyses sixteen sophomore student interviews and six teacher interviews to critically explore the conditions of English language education in Eritrea. Using an ecological perspective, the findings from this study highlight how the affective, didactic, study and linguistic conditions interrelate with one a…
On the ubiquitous presence of histone acetyltransferase B in eukaryotes
1985
AbstractHistone acetyltransferase B activity has been found in pea (Pisun sativum) seedlings. The enzyme has been partially purified and it has been found that it is highly specific for H4. The results confirm that histone acetyltransferase B occurs in 3 eukaryotic kingdoms.
Thiopurine
2020
Background: Thiopurine methyltransferase (TPMT) plays a significant role in the metabolism of thiopurines, and, for patients with inflammatory bowel disease (IBD), it is useful to perform TPMT genotyping prior to azathioprine (AZA) treatment. In this study, we determined TPMT gene polymorphisms in a cohort of IBD patients in Latvia. Methods: DNA samples were obtained from 244 IBD patients, and qPCR was performed for detection of rs1800462, rs1800460, and rs1142345 single-nucleotide polymorphisms (SNPs). Three common, non-functional TPMT alleles ( TPMT*2, *3B, and *3C) were identified (women, 51%; men, 49%). TPMT*2, *3A, *3B, and *3C allelic variants detected using qPCR were consistent with …
Parsimonious scenario for the emergence of viroid-like repliconsde novo
2019
AbstractViroids are small, non-coding, circular RNA molecules that infect plants. Different hypotheses for their evolutionary origin have been put forward, such as an early emergence in a precellular RNA World or severalde novoindependent evolutionary origins in plants. Here we discuss the plausibility ofde novoemergence of viroid-like replicons by giving theoretical support to the likelihood of different steps along a parsimonious evolutionary pathway. While Avsunviroidae-like structures are relatively easy to obtain through evolution of a population of random RNA sequences of fixed length, rod-like structures typical of Pospiviroidae are difficult to fix. Using different quantitative appr…
SAT0390 Microrna Expression Profile in Fibromyalgia Patients: A Pilot Matched Case Control Study
2013
Background Fibromyalgia (FM) is a clinical syndrome characterized by musculoskeletal pain and tenderness. Diagnosis is mainly based on exclusion of other resembling diseases since validated biological tests are still lacking. Identification of disease-related markers will enable clinicians to effectively diagnose FM, follow the progress of the disease, monitor the effects of therapeutic approaches and probably develop preventive programs. MicroRNAs (miRNAs) are pieces of 18-25 nucleotides capable of regulating gene expression. Changes in their expression levels have been linked to environmental responses as well as to pathological processes. Their recent association to some other chronic di…