Search results for "ERAS"
showing 10 items of 4431 documents
L'image de la culture finlandaise chez des étudiants français en échange Erasmus
2014
Vaihto-opiskelu ulkomaisessa korkeakoulussa on osa yhä useamman nuoren aikuisen kokemusmaailmaa. Yleisimmät motiivit vaihtoon lähtöön liittyvät usein kohdemaan kieleen ja kulttuuriin tutustumiseen sekä opiskelijan henkilökohtaiseen kehittymiseen. Tutkinkin pro gradu -tutkielmassani ranskalaisten Erasmus-vaihto-opiskelijoiden kuvaa suomalaisesta kulttuurista. Olen siis selvittänyt mitä kulttuuriteemoja he nostavat esille ja millainen Suomi-kuva opiskelijoilla on heidän kertomustensa perusteella. Tutkimusaineiston keräsin haastattelemalla kolmea ranskalaista Erasmus-opiskelijaa Jyväskylän yliopistolta. Aineistosta poimittiin teema-analyysiin kaikki sellaiset kertomukset ja kommentit, joissa k…
Äidinkielisten ja vieraskielisten tekstien referointi : luova kielenkäyttötehtävä vai tekstin osien kopioimista?
1997
NF-κB e Id2 como nodos de regulación de redes transcripcionales en diferentes modelos biológicos
2015
En el presente proyecto de tesis se ha contribuido a elucidar el importante papel que ejercen los nodos de regulación transcripcional en un contexto fisiológico en el que tienen lugar diferentes procesos biológicos, moleculares y celulares de forma simultánea y coordinada. Concretamente, se ha estudiado cómo dos inputs primarios, NF-κB e Id2, desencadenan un determinado output o proceso biológico concreto en la glándula mamaria y el hígado. Estudios previos describen un aumento de los niveles de actividad del factor transcripcional NF-κB durante el proceso de la involución de la glándula mamaria tras el ciclo embarazo/lactancia. Los resultados obtenidos demuestran que NF-κB tiene un papel i…
Acceso al empleo del colectivo de personas transexuales de Valencia: retos y barreras a superar en la sociedad actual
2017
Targeting the mevalonate pathway for improved anticancer therapy.
2009
The mevalonate pathway is important for the generation of isoprene moieties thereby providing the basis for the biosynthesis of molecules required for maintaining membrane integrity, steroid production and cell respiration. Additionally, isoprene precursors are indispensable for the prenylation of regulatory proteins such as Ras and Ras-homologous (Rho) GTPases. These low molecular GTP-binding proteins play key roles in numerous signal transduction pathways stimulated upon activation of cell surface receptors by ligand binding. Thus, Ras/Rho proteins eventually regulate cell proliferation, tumor progression and cell death induced by anticancer therapeutics. Lipid modification of Ras/Rho pro…
Rho GTPases: Promising Cellular Targets for Novel Anticancer Drugs
2006
Ras-homologous (Rho) GTPases play a pivotal role in the regulation of numerous cellular functions associated with malignant transformation and metastasis. Rho GTPases are localized at membranes and become activated upon stimulation of cell surface receptors. In their GTP-bound (=active) state, Rho proteins bind to effector proteins, thereby triggering specific cellular responses. Members of the Rho family of small GTPases are key regulators of actin reorganization, cell motility, cell-cell and cell-extracellular matrix (ECM) adhesion as well as of cell cycle progression, gene expression and apoptosis. Each of these functions is of importance for the development and progression of cancer. Fu…
Inhibition of Protein Isoprenylation Impairs Rho-Regulated Early Cellular Response to Genotoxic Stress
2000
Activation of c-Jun N-terminal kinases (JNKs) and nuclear factor-kappaB (NF-kappaB) are early cellular responses to genotoxic stress involved in the regulation of gene expression. Pretreatment of cells with the hydroxymethyl glutaryl-CoA reductase inhibitor lovastatin blocked stimulation of JNK1 activity by UV irradiation and by treatment with the alkylating compound methyl methanesulfonate but did not affect activation of extracellular signal-regulated kinase 2 by UV light. Lovastatin also attenuated UV-induced degradation of the NF-kappaB inhibitor IkappaBalpha. The effects of lovastatin on UV-triggered stimulation of JNK1 as well as on IkappaBalpha degradation were reverted by cotreatmen…
Chirurgische Ausbildung im digitalen Zeitalter – Virtual Reality, Augmented Reality und Robotik im Medizinstudium
2021
The digital transformation of healthcare is changing the medical profession. Augmented/Virtual Reality (AR/VR) and robotics are being increasingly used in different clinical contexts and require supporting education and training, which must begin within the medical school. There is currently a large discrepancy between the high demand and the number of scientifically proven concepts. The aim of this thesis was the conceptual design and structured evaluation of a newly developed learning/teaching concept for the digital transformation of medicine, with a special focus on the influence of surgical teaching.Thirty-five students participated in three courses of the blended learning curriculum "…
Klimata rīcībpolitikas barjeras Latvijā un to mazināšanas mehānismi
2017
Notikumi starptautiskajās klimata sarunās un ES ietvaros ir iezīmējuši ceļu uz oglekļa mazietilpīgu nākotni, bet tālāka attīstība ir nepieciešama gan starptautiskā, gan nacionālā līmenī. Barjeras klimata rīcībpolitiku ieviešanai ir izplatītas visā pasaulē, neatkarīgi no valsts ekonomiskā, tehnoloģiskā vai politiskā stāvokļa. Klimata politikas barjeras ietekmē klimata pārmaiņu risinājumu efektivitāti, godīgumu un ietekmi. Šis pētījums koncentrējas uz klimata rīcībpolitikas barjerām Latvijā, analizē to ietekmi un meklē risinājumus. Izmantojot ekspertu intervijas, aptaujas un politikas plānošanas dokumentu analīzi ir noskaidrots, ka Latvijā ir novērojamas visas literatūrā minētās barjeras, tom…