Search results for "ERROR"
showing 10 items of 1643 documents
2021
Abstract Reliable patient-specific ventricular repolarization times (RTs) can identify regions of functional block or afterdepolarizations, indicating arrhythmogenic cardiac tissue and the risk of sudden cardiac death. Unipolar electrograms (UEs) record electric potentials, and the Wyatt method has been shown to be accurate for estimating RT from a UE. High-pass filtering is an important step in processing UEs, however, it is known to distort the T-wave phase of the UE, which may compromise the accuracy of the Wyatt method. The aim of this study was to examine the effects of high-pass filtering, and improve RT estimates derived from filtered UEs. We first generated a comprehensive set of UE…
El silencio es de oro
2003
La mordaza antiterrorista
2002
L'Espagne fête trente ans de démocratie
2007
La chirigota política
2006
Visual mismatch negativity (vMMN): a prediction error signal in the visual modality
2015
Frontiers in Human Neuroscience, 8
Investigation on a MMACHC mutant from cblC disease: The c.394C>T variant
2022
The cblC disease is an inborn disorder of the vitamin B12 (cobalamin, Cbl) metabolism characterized by methylmalonic aciduria and homocystinuria. The clinical consequences of this disease are devastating and, even when early treated with current therapies, the affected children manifest symptoms involving vision, growth, and learning. The illness is caused by mutations in the gene codifying for MMACHC, a 282aa protein that transports and transforms the different Cbl forms. Here we present data on the structural properties of the truncated protein p.R132X resulting from the c.394C > T mutation that, along with c.271dupA and c.331C > T, is among the most common mutations in cblC. Althou…
Pharmacokinetics of the cannabinoid receptor ligand [18 F]MK-9470 in the rat brain - Evaluation of models using microPET
2018
PURPOSE The positron emission tomography ligand [18 F]MK-9470 is an inverse agonist that binds reversibly and with high affinity to the cannabinoid type 1 receptor. Due to its slow brain kinetics, care is required in the definition of its dissociation rates from the receptor. The goal of this study was to investigate pharmacokinetic analysis methods using an arterial input function. METHODS Five Sprague-Dawley rats received injections of 13 to 25 MBq of [18 F]MK-9470 and were scanned over a period of 90 min. Arterial blood samples were collected throughout the scan. Data were analyzed using four different compartmental models: a reversible one-tissue model, reversible two tissue models with…
An Aircraft Pilot Workload Sensing System
2021
The workload evaluation is of great importance for human error avoidance training, particularly in the use of complex systems that requires different and concurrent activities. The excessive workload harms human performance even with adverse outcomes. In the aviation field, certain flight maneuvers, such as take-off and landing, are characterized by great attention and workload demand to the pilot. Thus, a system capable of measuring pilots’ workload levels during flight could be beneficial to increase pilots’ performance. This work aims to study the initial feasibility of a device called Cockpit Pilot Warning System that monitors the pilot workload level during flight. With this aim, an ex…