Search results for "ESMO"
showing 10 items of 135 documents
24-(S)-hydroxycholesterol is a potent modulator of cholesterol metabolism in rat retinal Müller glia
2019
International audience
Evaluation of desmoglein 1 and 3 autoantibodies in pemphigus vulgaris: correlation with disease severity
2020
Background Pemphigus is an autoimmune blistering disease of the skin and mucous membranes caused by autoantibodies against desmoglein 1 (Dsg1) and desmoglein 3 (Dsg3). Pemphigus vulgaris (PV) is the most common form of pemphigus. The aim of this study was to assess the correlation between the levels of anti-desmoglein 1 and 3 autoantibodies and the severity of PV disease. Material and Methods Nineteen newly diagnosed patients with pemphigus vulgaris were enrolled in this study. The titers of Dsg in subjects by using enzyme-linked immunosorbent assay (ELISA) were done at diagnosis time-point, 4th and 8th weeks after the initiation of treatment, and the correlation of antibodies with the oral…
Fallberichte
2004
High-dose immunoglobulins (IVIG) are important agents in the treatment of numerous autoimmune disorders. In the field of dermatology, increasing numbers of patients with bullous autoimmune disorders and mixed connective tissue diseases have been treated. We successfully treated a patient with pemphigus vulgaris with IVIG, after he had developed osteonecrosis of his right femoral head while on azathioprine and corticosteroids. After reduction of oral corticosteroids, his disease flared dramatically. The addition of a high dose immunosuppressive regimen including azathioprine and dapsone failed to help. Thus high dose IVIG (2 mg/kg, 4 weeks interval) therapy was initiated and induced complete…
Latvijas virszemes un notekūdeņos izplatītāko farmaceitiski aktīvo vielu ekotoksikoloģiskā ietekme uz vienšūnas zaļaļģēm Desmodesmus subspicatus
2019
Farmaceitiskās vielas ir ķīmiski savienojumi, kas ir plaši izmantoti cilvēku un veterinārajā medicīnā. Pieaugot farmaceitisko līdzekļu ražošanai un izmantošanai, arī palielinās aktīvo farmaceitisko vielu (FAV) klātbūtne ūdens ekosistēmās, radot potenciālu apdraudējumu videi. Darba mērķis ir noteikt Latvijas virszemes un notekūdeņos izplatītāko farmaceitiski aktīvo vielu koncentrāciju individuālo ekotoksikoloģisko ietekmi uz vienšūnu zaļaļģēm Desmodesmus subspicatus Notekūdeņu un virszemes ūdeņu paraugiem, kas ievākti Lielupes sateces baseinā tika noteiktas FAV koncentrācijas. Pēc datu analīzes tika izvēlētas sešas FAV ar paaugstinātu koncentrāciju no trim terapeitisko līdzekļu grupām – anti…
Do evergetismo ao dom pro anima. Fundação de igrejas e esmola entre os séculos IV e VIII
2005
réédité dans «Do evergetismo ao dom pro anima. Fundação de igrejas e esmola entre os séculos IV e VIII», dans Relações de poder, educação e culture. Antigüidade e Idade Média. Estudos em homenagem ao Professor Daniel Valle Ribeiro, dir. Ruy de Oliveira Andrade Filho, São Paulo, Editora Solis, 2005, p. 269-276. halshs-00004646, v1; International audience
Phytosociologic method and Grazing Value of mediterranean rangelands: analysis of Ampelodesmos mauritanicus grasslands in Nebrodi Mountains (NE Sicil…
2007
Structure and Function of Desmosomes
2007
Desmosomes are prominent adhesion sites that are tightly associated with the cytoplasmic intermediate filament cytoskeleton providing mechanical stability in epithelia and also in several nonepithelial tissues such as cardiac muscle and meninges. They are unique in terms of ultrastructural appearance and molecular composition with cell type-specific variations. The dynamic assembly properties of desmosomes are important prerequisites for the acquisition and maintenance of tissue homeostasis. Disturbance of this equilibrium therefore not only compromises mechanical resilience but also affects many other tissue functions as becomes evident in various experimental scenarios and multiple diseas…
Pan-Asian adapted ESMO Clinical Practice Guidelines for the diagnosis treatment and follow-up of patients with localised colon cancer
2021
The most recent version of the European Society for Medical Oncology (ESMO) Clinical Practice Guidelines for the diagnosis, treatment and follow-up of localised colon cancer was published in 2020. It was decided by both the ESMO and the Japanese Society of Medical Oncology (JSMO) to convene a special virtual guidelines meeting in March 2021 to adapt the ESMO 2020 guidelines to take into account the ethnic differences associated with the treatment of localised colon cancer in Asian patients. These guidelines represent the consensus opinions reached by experts in the treatment of patients with localised colon cancer representing the oncological societies of Japan (JSMO), China (CSCO), India (…
A case report of desmoplastic ameloblastoma
2010
Ameloblastomas are the most common benign neoplasm of odontogenic nature. Desmoplastic ameloblastoma (DA) was included in the World Health Organization Classification of Head and Neck Tumors (WHO-2005) as a variant of ameloblastoma with specific clinical, image, and histological features. This case report focuses on a DA which occurred in the mandible of a 25 year-old man. The main signals and symptoms included painless swelling with buccal expansion and tooth displacement. Panoramic and periapical radiographs and cone-bean computed to- mography demonstrated an image mimicking a benign fibro-osseous lesion. The lower border of the mandible was not involved, but tooth displacement could be o…
Rapid hemodilution induced by desmopressin after erythropoietin administration in humans
2011
We have shown that treatment with desmopressin has a very effective hemodilution effect in healthy humans. These results led us to suggest the possible role of desmopressin to mask blood doping in sports. Based on our results, the World Anti-Doping Agency included the desmopressin in the 2011 List of Prohibited Substances and Methods. On this occasion, the aim of our study was to test the desmopressin-induced hemodilution after rHuEpo administration in humans. This was an intra-subject, crossover study in which five physically active males acted as their own controls. A basal blood sample was taken on their first visit to the laboratory. The next day, the subjects began the treatment. They …