Search results for "Earing"

Teprotumumab Efficacy, Safety, and Durability in Longer-Duration Thyroid Eye Disease and Re-treatment

2022

PURPOSE To evaluate teprotumumab safety/efficacy in patients with thyroid eye disease (TED) who were nonresponsive or who experienced a disease flare. DESIGN The Treatment of Graves' Orbitopathy to Reduce Proptosis with Teprotumumab Infusions in an Open-Label Clinical Extension Study (OPTIC-X) is a teprotumumab treatment and re-treatment trial following the placebo-controlled teprotumumab Phase 3 Treatment of Graves' Orbitopathy (Thyroid Eye Disease) to Reduce Proptosis with Teprotumumab Infusions in a Randomized, Placebo-Controlled, Clinical Study (OPTIC) trial. PARTICIPANTS Patients who previously received placebo (n = 37) or teprotumumab (n = 14) in OPTIC. METHODS OPTIC nonresponders or …

Optimal Population Growth as an Endogenous Discounting Problem: The Ramsey Case

2018

International audience; This paper revisits the optimal population size problem in a continuous time Ramsey setting with costly child rearing and both intergenerational and intertemporal altruism. The social welfare functions considered range from the Millian to the Benthamite. When population growth is endogenized, the associated optimal control problem involves an endogenous effective discount rate depending on past and current population growth rates, which makes preferences intertemporally dependent. We tackle this problem by using an appropriate maximum principle. Then we study the stationary solutions (balanced growth paths) and show the existence of two admissible solutions except in…

Balls into non-uniform bins

2014

Balls-into-bins games for uniform bins are widely used to model randomized load balancing strategies. Recently, balls-into-bins games have been analysed under the assumption that the selection probabilities for bins are not uniformly distributed. These new models are motivated by properties of many peer-to-peer (P2P) networks, which are not able to perfectly balance the load over the bins. While previous evaluations try to find strategies for uniform bins under non-uniform bin selection probabilities, this paper investigates heterogeneous bins, where the "capacities" of the bins might differ significantly. We show that heterogeneous environments can even help to distribute the load more eve…

Diagnosis of Incipient Bearing Faults using Convolutional Neural Networks

2019

The majority of faults occurring in rotating electrical machinery is attributed to bearings. To reduce downtime, it is desired to apply various diagnostic methods so that bearing degradation can be detected in good time prior to a complete failure. The work presented in this paper utilizes a data-driven machine learning approach based on convolutional neural networks (CNNs) in order to diagnose different types of bearing faults. A one-dimensional CNN is trained on vibration signals and compared to a two-dimensional CNN trained in time-frequency domain using continuous wavelet transform (CWT). The proposed method is demonstrated on data collected from run-to-failure tests.The results show th…

Generation and validation of syngeneic murine hepatoma cells bearing features of human HCC for rapid anti-HCC drug screening

2019

Organic Dye Bearing Asymmetric Double Donor-π-Acceptor Chains for Dye-Sensitized Solar Cells

2011

A novel efficient metal free sensitizer containing asymmetric double donor-π-acceptor chains (DC) was synthesized for dye-sensitized solar cells (DSSCs). Comparing to 3.80%, 4.40% and 4.64% for the DSSCs based on the dyes with single chain (SC1, SC2) and cosensitizers (SC1 + SC2), the overall conversion efficiency reaches 6.06% for DC-sensitized solar cells as a result of its longer electron lifetime and higher incident monochromatic photon-to-current conversion efficiency.

Objektīvās audiometrijas metode bērnu dzirdes traucējumu noteikšanā un attīstības rehabilitācijā

1999

Combinatorial Double Auction Radio Resource Allocation Model in Crowd Networks

2018

International audience; Industrial Partners (IPs) with Mobile Network Operators (MNOs) are extending the mobile network infrastructure with Small Cells (SCs) in order to meet the growing mobile traffic demand. Due to the increasing number of telecommunication market competitors and the scarcity of radio resources, static sharing schemes are no more efficient. New dynamic schemes should be considered to meet both user expectations and economic success. In a crowd networking context, we propose in this work a dynamic radio resource scheme based on combinatorial double auctions. The participants in these auctions are the MNOs considered as buyers and the IPs, providers of SCs, considered as se…

Ten Pillars of a Good Childhood: A Finnish Perspective

2012

Adapted from a presentation given at the Decade for Childhood 2012-2022 Launch during the Global Summit on Childhood, March 30, 2012, Washington, D.C. Author Note: The preparation of this paper has...

Life cycle assessment of low temperature asphalt mixtures for road pavement surfaces: A comparative analysis

2018

The increasing fuel consumption demand, the accelerated pressure imposed by the depletion of 5 scarce raw materials and the urgent environmental protection requirements are forcing the change of 6 pavement industry and academia community’s research endeavors towards the development of low 7 emissions road paving technologies able to significantly reduce mixing and compaction temperature as 8 well as the consumption of virgin raw materials. One set of relatively recent technologies in the field of 9 pavement materials that aims at addressing those concerns are the warm mix asphalt (WMA). In fact, 10 they have the potential to allow the reduction of energy consumption and airborne emissions d…