Search results for "Earing"

Effects of clearance on thick, single-lap bolted joints using through-the-thickness measuring techniques

2011

Composite materials have increasingly become more common in ground transportation. As this occured thicker panels, as compared to composite panels used in aviation, become necessary in order to withstand high impact loads and day to day degradation. The effectiveness of these panels was often limited by the strength of the joint in which the panel was attached to the frame of the vehicle. Investigating methods of reducing strain concentrations within these joints would increase the effectiveness in using composite materials in ground transportation applications by increasing the load necessary for joint failure to occur. In this study, fiber optic strain gages were embedded in a composite p…

Multiobjective design of distributed reactive power production in a deregulated electric market

2005

Abstract Reactive flows compensation optimal design for losses reduction in MV automated distribution systems is a problem deeply studied in literature. In this paper, the design problem is formulated considering the new deregulated energy market. These new operational conditions allow the MV grid operator to consider the generation of reactive energy also as a service that can be sold to the transmission system above. In this case, the transmission system would be helped in all the working conditions in which a strong modulation of the reactive flow through the HV/MV node is required. Then, for the MV grid operator, the compensation system optimal design problem is therefore that of the se…

Numerical Analysis of Bearing Capacity of a Ring Footing on Geogrid Reinforced Sand

2021

A ring footing is found to be of practical importance in supporting symmetrical constructions for example silos, oil storage container etc. In the present paper, numerical analysis was carried out with explicit code FLAC3D 7.0 to investigate bearing capacity of a ring footing on geogrid reinforced sand. Effects of the ratio n of its inner/outer diameter (Di/D) of a ring footing, an optimum depth to lay the geogrid layer were examined. It was found that an intersection zone was developed in soil under inner-side (aisle) of ring footing, contributing to its bearing capacity. Substantial increase of bearing capacities could be realized if ratio n of a ring footing was around 0.6. Numerical res…

How not to give up on train travel when you are deaf ?

2015

TRANSED 2015 - 14th International Conference on Mobility and Transport for Elderly and Disabled Persons, LISBONNE, PORTUGAL, 28-/07/2015 - 31/07/2015; The SUrDyn project aims at the design of an innovative visual information system, dedicated to travelers who cannot hear or understand audio disrupted announcements (e.g. cancellation, delay...) when they are in train stations. It is based on two previously developed systems: the Jade signer avatar, which informs travelers in French Signs Language, and an animated graphics translation. The objective is to combine these two approaches, in an optimal manner. We proposed a comprehension task to 159 participants divided in three groups: 53 deaf p…

Linguistic, psychometric validation and diagnostic ability assessment of an Italian version of a 19-item wearing-off questionnaire for wearing-off de…

2012

Endothelial nitric oxide synthase upregulation in the guinea pig organ of Corti after acute noise trauma.

2004

Endothelial nitric oxide synthase (eNOS) upregulation was identified 60 h after acute noise trauma in morphologically intact cells of the reticular lamina in the organ of Corti of the guinea pig in the second turn of the cochlea. Using gold-coupled anti-eNOS antibodies and electron microscopy, it was shown that eNOS expression was upregulated in all cell areas and cell types except inner hair cells. Furthermore, eNOS was found in the organelle-free cytoplasm and in mitochondria of various cell types. The density of eNOS in mitochondria was considerably higher compared with the surrounding cytoplasm. Since eNOS activity is regulated by calcium, the eNOS detection was combined with calcium pr…

Young woman with Branchio-Oto-Renal Syndrome and a novel mutation in the EYA-1 gene

2011

Branchio-oto-renal (BOR) syndrome is an autosomal dominant disease clinically characterized by the coexistence of some or all of the following major disorders: deafness, cervical branchial fistulae, preauricular pits, and renal abnormalities. Most families with BOR syndrome have mutations on the EYA-1 gene on chromosome 8q. We present the case of a 23-year-old Italian woman without a familial history of BOR syndrome. The patient, who had hearing loss and a history of surgeries for correction of bilateral cervical branchial fistulae and bilateral preauricular pits, presented with renal impairment, hypertension and overt proteinuria. DNA sequencing showed a novel heterozygous mutation 1420-14…

SAT0513 Brainstem Auditory Evoked Potentials and Visual Potentials in Kawasaki Disease: Expression of CNS Vasculitis?

2015

Background Kawasaki disease (KD) is an acute, self-limited vasculitis of infants and children that is nowadays the most common cause of acquired heart disease in children. Transient sensorineural hearing loss (20 to 35 dB) is a possible complication of acute phase KD and may be related to salicylate toxicity in some patients. Objectives Brainstem Auditory Evoked Potentials (BAEPs) , and Visual Evoked Potentials (VEPs) were examined in 43 children (age: 0,8-7,5 years) affected by KD. No risk factors for hearing loss and/or neurological impairment of CNS were identified in all the patients. BAEPs showed altered waves II to V, in 18 patients (42%). Among these, in 4 patients (20%) VEPs showed …

Haploinsufficiency of 16.4 Mb from chromosome 22pter-q11.21 in a girl with unilateral conductive hearing loss.

2009

We present the postnatal diagnosis of a de novo der(18)t(18;22)(p11.32;q11.21)pat, resulting in an unbalanced 45,XX,der (18)t(18;22) karyotype in a girl with conductive hearing loss on the left and ptosis of the right upper eye-lid. Unilateral ptosis was also observed in the patient’s 2 years and 8 months younger sister, who grows noticeably faster and appears to be a much quicker learner. After speech therapy the patient was eventually placed in normal school. The haploinsufficient 16.4-Mb region on chromosome 22pter→q11.21 contains 10 genes as well as many predicted genes, pseudogenes, and retrotransposed sequences with unknown functions. This observation may prove useful for prenatal dia…

89 Zr-Immuno-Positron Emission Tomography in Oncology: State-of-the-Art 89 Zr Radiochemistry

2017

Contains fulltext : 181624.pdf (Publisher’s version ) (Open Access) Immuno-positron emission tomography (immunoPET) with (89)Zr-labeled antibodies has shown great potential in cancer imaging. It can provide important information about the pharmacokinetics and tumor-targeting properties of monoclonal antibodies and may help in anticipating on toxicity. Furthermore, it allows accurate dose planning for individualized radioimmunotherapy and may aid in patient selection and early-response monitoring for targeted therapies. The most commonly used chelator for (89)Zr is desferrioxamine (DFO). Preclinical studies have shown that DFO is not an ideal chelator because the (89)Zr-DFO complex is partly…