Search results for "Echinodermata"
showing 4 items of 34 documents
Could the acid-base status of Antarctic sea urchins indicate a better-than-expected resilience to near-future ocean acidification?
2015
13 pages; International audience; Increasing atmospheric carbon dioxide concentration alters the chemistry of the oceans towards more acidic conditions. Polar oceans are particularly affected due to their low temperature, low carbonate content and mixing patterns, for instance upwellings. Calcifying organisms are expected to be highly impacted by the decrease in the oceans' pH and carbonate ions concentration. In particular, sea urchins, members of the phylum Echinodermata, are hypothesized to be at risk due to their high-magnesium calcite skeleton. However, tolerance to ocean acidification in metazoans is first linked to acid–base regulation capacities of the extracellular fluids. No infor…
Histone Deacetylase Inhibitors
2020
Histone deacetylases (HDACs) are key components of the epigenetic machinery controlling gene expression. They are involved in chromatin remodeling events via post-translational histone modifications but may also act on nonhistone proteins, influencing many fundamental cellular processes. Due to the key involvement of HDACs in serious human pathologies, including cancer, HDAC inhibitors (HDACis) have received increased attention in recent years. It is known that marine invertebrates produce significant amounts of secondary metabolites showing active pharmacological properties and an extensive spectrum of biomedical applications. Some of these compounds possess HDACi properties.
SOME COMPARATIVE REMARKS ON THE TRANSIENT CHANGE IN LACTIC ACID CONTENT IN SEA URCHIN EGGS FOLLOWING FERTILIZATION.
1964
Abstract During the first few minutes following fertilization a transient increase in the concentration of lactic acid occurs in the eggs of Arbacia lixula , whereas no change at all is observed in the eggs of Paracentrotus liuidus . In the eggs of Psammechinus miliaris there is a transient decrease, soon followed by a recovery so that the level of the unfertilized egg is again reached.
Analysis of the effects of co-exposure to antibiotics and cadmium on sea urchin embryos
2014
In order to understand the mechanisms of responses to changes in the physical and chemical environment, as well as the mechanisms of developmental pathways, we investigated by RT-qPCR assays and light microscopy observations the impact of antibiotics and cadmium in P. lividus sea urchin embryos. In particular we inspected development and biomarkers for free radical damage and apoptosis. During development embryos were exposed to an antibiotic mix (Ab mix, usually added to sea urchin cultures) or to sulfamethoxazole/trimethoprim mix (TMP/SMX, usually added to aquacultures) and/or levels of 10-5, 10-4, 10-3 M CdCl2. Even though treatment with TMP/SMX apparently did not affect development, it …