Search results for "Effect"
showing 10 items of 9072 documents
Resuscitative endovascular balloon occlusion of the aorta (REBOA) in patients with major trauma and uncontrolled haemorrhagic shock: a systematic rev…
2021
AbstractBackgroundMultiple studies regarding the use of Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) in patients with non-compressible torso injuries and uncontrolled haemorrhagic shock were recently published. To date, the clinical evidence of the efficacy of REBOA is still debated. We aimed to conduct a systematic review assessing the clinical efficacy and safety of REBOA in patients with major trauma and uncontrolled haemorrhagic shock.MethodsWe systematically searched MEDLINE (PubMed), EMBASE and CENTRAL up to June 2020. All randomized controlled trials and observational studies that investigated the use of REBOA compared to resuscitative thoracotomy (RT) with/witho…
Hydro-mechanical modelling of a natural slope affected by a multiple slip surface failure mechanism
2009
A coupled hydro-mechanical formulation is presented for the analysis of landslide motion during crisis episodes. The mathematical formulation is used to model a natural slope affected by a multiple slip surface failure mechanism, in which pore water pressure evolution was identified as the main cause for movement accelerations. An elasto-plastic constitutive model is adopted for the behaviour of slip surfaces. Material parameters are obtained by combining the available laboratory tests and the back analysis of some crisis episodes. After being calibrated and validated, the model is applied to improve the understanding of the physical processes involved and to predict the landslide behaviour…
An effective stress based shear strength criterion for unsaturated compacted double-porosity clays
2015
An effective stress based shear strength criterion is proposed taking into account the fundamental effects of microstructure characteristics on retention properties of compacted double-porosity clays and their overall coupled hydro-mechanical behaviour. Results of triaxial compression tests carried out on saturated and unsaturated samples of a compacted scaly clay show that points representative of failure conditions depict a unique failure envelope when the macropore degree of saturation is used in the definition of the effective stress and its evolution with the suction is taken into account. Furthermore, the proposed criterion is very effective to consider the most relevant aspects of su…
Pathways for the amplification of agroecology in African sustainable urban agriculture
2020
A growing awareness that highly intensified agricultural systems have made a substantial worldwide contribution to the worsening of the resilience capacity of natural ecosystems has, over the last twenty years, brought general attention to agroecological management models. This aspect is even more evident in industrial agriculture, which is based on the use of multiple chemical products derived from non-natural synthesis. In more developed countries, a new idea of ecology linked to agricultural production has been increasingly developed and, for this reason, there has been a greater diffusion of differentiated agricultural models taking into consideration the environmental impact of product…
La rilevanza degli interessi moratori nel giudizio di usura in astratto
2020
La Sezione I della Cassazione ha rimesso alle Sezioni unite le questioni relative alla rilevanza usuraria degli interessi moratori, alla configurabilità o meno del c.d. principio di simmetria e all’eventuale individuazione di un tasso usura ad hoc per gli interessi moratori. A fronte di tali interrogativi, va rimarcata invece la conformità al sistema della disciplina contro l’usura tanto della rilevanza usuraria degli interessi moratori quanto della necessità della loro valutazione congiunta alle altre voci di remunerazione, di costo o di spesa, cui non osta la mancata inclusione degli interessi moratori all’interno del tasso effettivo globale medio della categoria omogenea di operazioni al…
Could PD-1/PDL1 immune checkpoints be linked to HLA signature?
2019
The outstanding clinical expansion of monoclonal antibodies (mAbs) to programmed cell death receptor-1 (PD-1) (nivolumab and pembrolizumab) and PD-1 ligand-1 (PDL-1) (atezolizumab, avelumab and durvalumab) has received an increasing level of interest regarding immunotherapy and multidrug combinations, for the treatment of a number of common human malignancies. Some patients treated with these agents receive remarkable benefits in term of quality of life, progression-free (PFS) and overall survival (OS). However, a significant percentage of these patients experience immune-related adverse events (irAEs), while others present with an ultra-rapid disease progression, defined as hyperprogressio…
Referee efficacy in the context of Norwegian soccer referees – A meaningful construct?
2018
Abstract Objectives The purpose of this study was two-fold. Firstly, to examine the measurement/factorial validity and invariance of the Referee Self-Efficacy Scale (REFS) among Norwegian soccer referees. Secondly, extending scale validation, we also tested a structural model in which a second-order version of the REFS was modelled to mediate a set of theoretically informed antecedents and outcomes. Design Cross-sectional. Method One hundred and eleven Norwegian elite referees and 81 non-elite referees completed an electronic questionnaire measuring expected antecedents and outcomes of perceived self-efficacy in the role as referees. Results Analyses provided support for the first – and sec…
Utility of Alternative Effect Size Statistics and the Development of a Web-Based Calculator: Shiny-AESC
2018
Alternative displays of effect size statistics can enhance the understandability and impact of validity evidence in a variety of applied settings. Arguably, the proliferation of alternative effect size statistics has been limited due to the lack of user-friendly tools to create them. Common statistical packages do not readily produce these alternative effect sizes and existing tools are outdated and inaccessible. In this paper, I introduce a free-to-use web-based calculator (https://dczhang.shinyapps.io/expectancyApp/) for generating alternative effect size displays from empirical data. This calculator requires no mathematical or programming expertise, and therefore, is ideal for academics …
Students’ Perceptions of Instructional Rubrics in Neurological Physical Therapy and Their Effects on Students’ Engagement and Course Satisfaction
2021
One of the main challenges faced by physical therapy (PT) students is to learn the practical skills involved in neurological physical therapy (PT). To help them to acquire these skills, a set of rubrics were designed for formative purposes. This paper presents the process followed in the creation of these rubrics and their application in the classroom, noting that students perceived them as valid, reliable, and highly useful for learning. The perception of the validity and usefulness of the rubrics has different closely related dimensions, showing homogeneous values across the students´ sociodemographic and educational variables, with the exception of dedication to studying, which showed a …