Search results for "Elasticity"

showing 10 items of 736 documents

Thermo-responsive hydrogels from cellulose-based polyelectrolytes and catanionic vesicles for biomedical application.

2016

In this study, negatively charged catanionic vesicles/hydrophobically modified hydroxyethylcellulose polymers thermo-responsive hydrogels have been fabricated. Vesicular aggregates were found to act as multifunctional junctions for networking of modified-cellulose water solutions. The contributions of the electrostatic and hydrophobic interactions were evaluated by changing either vesicles composition or the polymer hydrophobic substitution. Thermal-induced size and lamellarity of hydrogel-enclosed vesicles were detected, with further polygonal shape changes induced by cellulose-based polymer addition. The thermal transition was also found to tune hydrogel mechanical behaviour. The network …

AnionsProton Magnetic Resonance SpectroscopyBiomedical EngineeringBiomedical TechnologyCeramics and CompositeBiomaterialsDiffusioncatanionic vesicleTheophyllineCationsCellulosecatanionic vesicles; cellulose; diffusion; hydrogel; NMR; rheology; Ceramics and Composites; Biomaterials; Biomedical Engineering; 2506ViscositydiffusionTemperatureHydrogelsBiomaterialPolyelectrolytescelluloseNMRElasticityDrug LiberationSettore CHIM/09 - Farmaceutico Tecnologico Applicativocatanionic vesiclesCeramics and Compositesrheologyhydrogel2506RheologyJournal of biomedical materials research. Part A
researchProduct

RESIST-HCV Criteria to Monitor Progression of Low-Risk Esophageal Varices in Patients With Compensated Cirrhosis After HCV Eradication: The SIMPLE St…

2022

Noninvasive criteria to predict the progression of low-risk esophageal varices (EV) in patients with compensated hepatitis C virus (HCV) cirrhosis after sustained virological response (SVR) by direct-acting antivirals (DAAs) are lacking. Our aim was to assess the diagnostic performance of Rete Sicilia Selezione Terapia-HCV (RESIST-HCV) criteria for EV progression compared with elastography-based criteria (Baveno VI, Expanded Baveno VI, and Baveno VII-HCV criteria).All consecutive patients observed at 3 referral centers with compensated HCV cirrhosis with or without F1 EV who achieved sustained virological response by DAAs were classified at last esophagogastroduodenoscopy (EGDS) as RESIST-H…

Antiviral AgentMaleLiver CirrhosisHepatologyPlatelet CountLiver CirrhosiGastroenterologyHepacivirusHepatitis C ChronicEsophageal and Gastric VaricesAntiviral AgentsElasticity Imaging Techniques.Esophageal and Gastric VariceHumansElasticity Imaging TechniquesFemaleSerum AlbuminHumanAgedThe American journal of gastroenterology
researchProduct

Comparison of hemodynamic and structural indices of ascending thoracic aortic aneurysm as predicted by 2-way FSI, CFD rigid wall simulation and patie…

2018

Patient-specific computational modeling is increasingly being used to predict structural and hemodynamic parameters, especially when current clinical tools are not accessible. Indeed, pathophysiology of ascending thoracic aortic aneurysm (ATAA) has been simulated to quantify the risk of complications by novel prognostic parameters and thus to improve the clinical decision-making process related to the intervention of ATAAs. In this study, the relevance of aneurysmal wall elasticity in determining parameters of clinical importance, such as the wall shear stress (WSS), is discussed together with the significance of applying realistic boundary conditions to consider the aortic stretch and twis…

Aortic valveAdultMalePatient-Specific Modelingmedicine.medical_specialtyComputer science0206 medical engineeringFinite Element Analysisaorti failureHeart Valve DiseasesHemodynamicsFluid-solid interaction (FSI)Health Informatics02 engineering and technology030204 cardiovascular system & hematologyComputational fluid dynamicsThoracic aortic aneurysm03 medical and health sciences0302 clinical medicineBicuspid aortic valveBicuspid Aortic Valve DiseaseInternal medicinemedicineShear stressHumansComputer SimulationAgedAortic Aneurysm ThoracicStructural mechanicsbusiness.industryFinite element analysis (FEA)Models CardiovascularMiddle Agedmedicine.diseaseAscending thoracic aortic aneurysm020601 biomedical engineeringFinite element methodElasticityComputer Science Applicationsmedicine.anatomical_structureComputational fluid-dynamic (CFD)Aortic Valvecardiovascular systemCardiologyFemaleStress Mechanicalbusiness
researchProduct

Difference in hemodynamic and wall stress of ascending thoracic aortic aneurysms with bicuspid and tricuspid aortic valve.

2012

The aortic dissection (AoD) of an ascending thoracic aortic aneurysm (ATAA) initiates when the hemodynamic loads exerted on the aneurysmal wall overcome the adhesive forces holding the elastic layers together. Parallel coupled, two-way fluid–structure interaction (FSI) analyses were performed on patient-specific ATAAs obtained from patients with either bicuspid aortic valve (BAV) or tricuspid aortic valve (TAV) to evaluate hemodynamic predictors and wall stresses imparting aneurysm enlargement and AoD. Results showed a left-handed circumferential flow with slower-moving helical pattern in the aneurysm's center for BAV ATAAs whereas a slight deviation of the blood flow toward the anterolater…

Aortic valveMalemedicine.medical_specialtyFluid–structure interaction Aortic dissection Ascending thoracic aortic aneurysm Bicuspid aortic valveBiomedical EngineeringBiophysicsHeart Valve DiseasesAorta ThoracicThoracic aortic aneurysmArticleAortic aneurysmBicuspid aortic valveBicuspid Aortic Valve DiseaseInternal medicinemedicine.arteryCoronary CirculationAscending aortamedicineThoracic aortaHumansOrthopedics and Sports Medicinecardiovascular diseasesAgedAortic dissectionAortabusiness.industryRehabilitationHemodynamicsModels CardiovascularMiddle Agedmedicine.diseaseElasticityAortic Aneurysmmedicine.anatomical_structureAortic ValveCardiologycardiovascular systemFemaleTricuspid ValvebusinessJournal of biomechanics
researchProduct

A strain-difference-based nonlocal elasticity model

2004

Abstract A two-component local/nonlocal constitutive model for (macroscopically) inhomogeneous linear elastic materials (but constant internal length) is proposed, in which the stress is the sum of the local stress and a nonlocal-type stress expressed in terms of the strain difference field, hence identically vanishing in the case of uniform strain. Attention is focused upon the particular case of piecewise homogeneous material. The proposed model is thermodynamically consistent with a suitable free energy potential. It constitutes an improved form of the Vermeer and Brinkgreve [A new effective nonlocal strain measure for softening plasticity. In: Chambon, R., Desrues, J., Vardulakis, I. (E…

Applied MathematicsMechanical EngineeringAttenuationMathematical analysisConstitutive equationLinear elasticityGeometryPlasticityCondensed Matter PhysicsBifurcation theoryMechanics of MaterialsModeling and SimulationPiecewiseGeneral Materials ScienceSofteningMathematicsNumerical stabilityInternational Journal of Solids and Structures
researchProduct

Nonlocal elasticity and related variational principles

2001

Abstract The Eringen model of nonlocal elasticity is considered and its implications in solid mechanics studied. The model is refined by assuming an attenuation function depending on the `geodetical distance' between material particles, such that in the diffusion processes of the nonlocality effects certain obstacles as holes or cracks existing in the domain can be circumvented. A suitable thermodynamic framework with nonlocality is also envisaged as a firm basis of the model. The nonlocal elasticity boundary-value problem for infinitesimal displacements and quasi-static loads is addressed and the conditions for the solution uniqueness are established. Three variational principles, nonlocal…

Applied MathematicsMechanical EngineeringCondensed Matter PhysicsFinite element methodQuantum nonlocalityClassical mechanicsMechanics of MaterialsVariational principleModeling and SimulationSolid mechanicsGeneral Materials ScienceDirect stiffness methodUniquenessElasticity (economics)MathematicsStiffness matrixInternational Journal of Solids and Structures
researchProduct

Gradient elasticity and nonstandard boundary conditions

2003

Abstract Gradient elasticity for a second gradient model is addressed within a suitable thermodynamic framework apt to account for nonlocality. The pertinent thermodynamic restrictions upon the gradient constitutive equations are derived, which are shown to include, besides the field (differential) stress–strain laws, a set of nonstandard boundary conditions. Consistently with the latter thermodynamic requirements, a surface layer with membrane stresses is envisioned in the strained body, which together with the above nonstandard boundary conditions make the body constitutively insulated (i.e. no long distance energy flows out of the boundary surface due to nonlocality). The total strain en…

Applied MathematicsMechanical EngineeringConstitutive equationGeometryMechanicsEquilibrium equationCondensed Matter PhysicsTotal strainMinimum total potential energy principleQuantum nonlocalityMechanics of MaterialsModeling and SimulationGeneral Materials ScienceBoundary value problemSurface layerElasticity (economics)MathematicsInternational Journal of Solids and Structures
researchProduct

ON THE EFFECTS OF A CRACK PROPAGATING TOWARD THE INTERFACE OF A BIMATERIAL SYSTEM

2006

This paper deals with the influence of matrix cracks on the failure mode of bimaterial systems and composite materials. In order to investigate such an influence, the stress field near a crack embedded into the more yielding material and propagating perpendicularly to the interface, has been analyzed by using systematic numerical simulations. Such analysis has shown that the crack propagation give rises to transversal stresses that can damage the reinforcing materials when this has low modulus, as glass fibers, or low transversal strength, such as carbon fibers. Moreover, the longitudinal stress concentration can damage the reinforcing material only if this has high stiffness, as in the cas…

AramidStress fieldPhotoelasticityMaterials scienceMechanics of MaterialsMechanical EngineeringGlass fiberPerpendicularGeneral Materials ScienceFracture mechanicsFiberComposite materialFailure mode and effects analysis
researchProduct

Influence of the metabolic syndrome on aortic stiffness in never treated hypertensive patients

2004

Summary Background and aim Metabolic syndrome (MS) carries an increased risk for cardiovascular events and there is a growing awareness that large artery stiffening is a powerful predictor of cardiovascular morbidity and mortality. Little is known about the relationship of MS with aortic stiffness. The aim of our study was to analyze, in patients with essential hypertension, the influence of MS, defined according to the criteria proposed by the Third Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (NCEP-ATP III), on carotid–femoral pulse wave velocity (PWV), a measure of aortic stiffness. Methods N…

Arterial hypertensionAdultMalemedicine.medical_specialtySettore MED/09 - Medicina InternaAmbulatory blood pressureEndocrinology Diabetes and MetabolismMedicine (miscellaneous)Essential hypertensionRisk FactorsInternal medicineDiabetes mellitusmedicineAlbuminuriaHumansPulse wave velocityNational Cholesterol Education ProgramAortaMetabolic SyndromeNutrition and Dieteticsbusiness.industryAge FactorsBlood Pressure Monitoring AmbulatoryMiddle AgedCardiovascular riskmedicine.diseaseSettore MED/11 - Malattie Dell'Apparato CardiovascolareElasticityFemoral ArteryPulse wave velocityAortic stiffneCarotid ArteriesBlood pressureEndocrinologyDiabetes Mellitus Type 2Blood chemistryCase-Control StudiesHypertensionCardiologyRegression AnalysisFemaleMetabolic syndromeCardiology and Cardiovascular MedicinebusinessNutrition, Metabolism and Cardiovascular Diseases
researchProduct

Distributed Consensus in Networks of Dynamic Agents

2006

Stationary and distributed consensus protocols for a network of n dynamic agents under local information is considered. Consensus must be reached on a group decision value returned by a function of the agents' initial state values. As a main contribution we show that the agents can reach consensus if the value of such a function computed over the agents' state trajectories is time invariant. We use this basic result to introduce a protocol design rule allowing consensus on a quite general set of values. Such a set includes, e.g., any generalized mean of order p of the agents' initial states. We demonstrate that the asymptotical consensus is reached via a Lyapunov approach. Finally we perfor…

Asymptotic stability; Distributed consensus protocolsEngineeringMathematical optimizationAsymptotic stabilitybusiness.industryFunction (mathematics)Network topologyUniform consensusComputer Science::Multiagent SystemsLTI system theorySet (abstract data type)Distributed consensus protocolsConsensusExponential stabilityComputer Science::Systems and ControlControl theoryexperimental mechanics Fourier transform load stepping photoelasticityGeneralized meanbusinessProceedings of the 44th IEEE Conference on Decision and Control
researchProduct