Search results for "Elda"

Inside the Hsp90 inhibitors binding mode through induced fit docking

2009

Abstract During the last few decades, the development of new anticancer strategies had to face the instability of many tumors, occurring when the genetic plasticity of cells produces new drug-resistant cancers. It has been shown that a chaperone protein, heat shock protein 90 (Hsp90), is one of the fundamental factors involved in the cell response to stresses, and its role in many biochemical pathways has been demonstrated. Thus, the inhibition of Hsp90 represents a new target of antitumor therapy, since it may influence many specific signaling pathways. The natural antibiotic Geldanamycin is the first Hsp90 inhibitor that has been identified. Nevertheless, more potent and water-soluble sma…

Detailed internal characterisation of two Finnish landfills by waste sampling

2006

The aim of this study was to characterise the internal structure and composition of landfilled waste at two Finnish landfills to provide information for active and post-landfill operations. The two sites, Ammässuo and Kujala, have been in operation for 17 and 48 years, respectively. Waste was sampled (total 68 samples) and analysed for total solids (TS), volatile solids (VS), total Kjeldahl nitrogen (TKN), biological methane potential (BMP) and leaching of organic material (determined as chemical oxygen demand, COD) and ammonium nitrogen (NH(4)-N). The results showed high vertical and horizontal variability, which indicated that both the waste composition and state of degradation varied gre…

(Re-)Balancing the Triforce : Gender representation and androgynous masculinity in the Legend of Zelda series

2019

The Legend of Zelda series is one of the most beloved and acclaimed Japanese video game franchises in the world. The series’ protagonist is an androgynous male character, though recent conversations between Nintendo and players have focused on gender representation in the newest title in the series, Breath of the Wild. Considering these discussions, this article provides an analysis of Link, the protagonist and player character of The Legend of Zelda series. This analysis includes a discussion of the character’s androgynous design, its historical context, official Nintendo paratextual material, developer interviews, and commentary from fans and critics of the series. As an iconic androgynou…

Zvaigžņotā Debess: 2017/18, Ziema (238)

2017

Contents: “ZVAIGŽŅOTĀ DEBESS” FORTY YEARS AGO: I.Vilka. Starry Sky and Birds’ Journeys (abridged) ; N.Cimahoviča. Spirals of Saturn’s Rings (abridged) ; I.Šmelds. V Readings of Friedrich Zander ; DEVELOPMENTS in SCIENCE: K.Schwartz. Most Distant Galaxy Clusters and 3D Structure of the Universe ; DISCOVERIES: M.Gills. The Day when Multi-Messenger Astronomy Was Announced ; I.Pundure. ESO Telescopes and Hubble Observe the Source of Gravitational Waves for the First Time ; I.Eglītis. Asteroid “Balklavs” ; SPACE RESEARCH and EXPLORATION: R.Misa. Mission of Cassini – Discoveries to the Very End ; J.Jaunbergs. The Icy World Tethys ; OBSERVATORIES and INSTRUMENTS: M.Gills. The Giant Radio Telescope…

Nātrija-bismuta titanātu saturošu cieto šķīdumu struktūra

2015

Maģistra darbā ar rentgendifrakcijas metodi ir pētītas divas cieto šķīdumu sistēmas - Na1/2Bi1/2TiO3-SrTiO3–PbTiO3 un Na1/2Bi1/2TiO3-CaTiO3. Difrakcijas ainu analīzei izmantota Ritvelda metode. Cietajos šķīdumos atkarībā no cietā šķīduma sastāva novēro gan plašus kristālisko fāzu koeksistences temperatūru intervālus, gan asas fāzu pārejas. Na1/2Bi1/2TiO3-SrTiO3–PbTiO3 cieto šķīdumu sistēmā novērojams gan paraelektrisks, gan relaksora, gan segnetoelektrisks stāvoklis atkarībā no sastāva. Abās sistēmās veikti rentgendifrakcijas mērījumi un to analīze cietajiem šķīdumiem, uz kuriem iedarbojas elektriskais lauks. Polarizētam Na1/2Bi1/2TiO3 novēro fāzu pāreju uz literatūrā neminētu makroskopisku…

Diode laser welding of ABS: Experiments and process modeling

2009

International audience; The laser beam weldability of acrylonitrile/butadiene/styrene (ABS) plates is determined by combining both experimental and theoretical aspects. In modeling the process, an optical model is used to determine how the laser beam is attenuated by the first material and to obtain the laser beam profile at the interface. Using this information as the input data to a thermal model, the evolution of the temperature field within the two components can be estimated. The thermal model is based on the first principles of heat transfer and utilizes the temperature variation laws of material properties. Corroborating the numerical results with the experimental results, some impor…

Gozos al santisimo Cristo del Buen Suceso de Elda.

El full orlat Grav. xil. enmarcat del "SS. Christo del Buen Sucesso de Elda", flanquejat per gerros amb flors Text del goig a tres col. separades per filets

The Major Heat Shock Proteins, Hsp70 and Hsp90, in 2-Methoxyestradiol-Mediated Osteosarcoma Cell Death Model

2020

2-Methoxyestradiol is one of the natural 17&beta

Azoto

2015

1. Introduzione p. 282 2. Determinazione dell’azoto totale con analizzatore elementare p. 284 3. Determinazione dell’azoto totale con metodo semi-micro-Kjeldahl p. 284 4. Determinazione dell’azoto totale con metodo semi-micro-Kjeldahl modificato p. 287 5. Determinazione dell’azoto totale estraibile con soluzione salina con metodo micro-Kjeldahl p. 291 6. Determinazione dell’azoto totale estraibile con soluzione salina con metodo micro-Kjeldahl modificato p.294 7. Determinazione colorimetrica degli ioni ammonio estraibili p. 296 8. Determinazione colorimetrica degli ioni nitrato estraibili p. 298 9. Estrazione dell’azoto totale idrolizzabile con acido cloridrico p. 300 10.Determinazione dell…

Two-stage anaerobic digestion of tomato, cucumber, common reed and grass silage in leach-bed reactors and upflow anaerobic sludge blanket reactors

2010

Abstract Anaerobic digestion of tomato, cucumber, common reed and grass silage was studied in four separate two-stage reactor configuration consisting of leach bed reactor (LBR) and upflow anaerobic sludge blanket reactor (UASB). LBR studies showed that COD solubilization for cucumber and grass silage was higher (50%) than tomato (35%) and common reed (15%). Results also showed that 31–39% of initial TKN present in tomato and cucumber was solubilized in the leachates and 47–54% of the solubilized TKN was converted to NH4-N. The corresponding values for common reed and grass silage were 38–50% and 18–36%, respectively. Biomethanation of the leachates in UASB reactors resulted in methane yiel…