Search results for "Elderly"

showing 10 items of 872 documents

Everolimus (EVE) and exemestane (EXE) in patients with advanced breast cancer aged ≥ 65 years: New lessons for clinical practice from the EVA study

2018

BACKGROUND: The present analysis focuses on real-world data of Everolimus- Exemestane in advanced HR+ve, HER2-ve elderly breast cancer patients (aged 65 years) included in the EVA study, with unique findings in those aged 70 years. METHODS: Data are collected from clinical records and analysed according to age cut-off (< 65 years; 65 - 69 years and [greater than or equal to] 70 years). Relationship of analyzed variables with response were tested by mean of a Mantel- Haenszel chi square test. Time to event analysis was described by Kaplan Meier approach and association with baseline characteristics was analysed by stratified log-rank test and proportional hazard model. RESULTS: From July …

medicine.medical_specialtySocio-culturaleHormone-receptor positiveExemestane03 medical and health scienceschemistry.chemical_compound0302 clinical medicineBreast cancerElderlyExemestaneWeight lossInternal medicineAdvanced breast cancer; Elderly; Everolimus; Exemestane; Hormone-receptor positive; OncologymedicineEverolimus030212 general & internal medicineStomatitisPneumonitisAdvanced breast cancer; Elderly; Everolimus; Exemestane; Hormone-receptor positiveEverolimusbusiness.industryCancermedicine.diseaseRashEverolimuchemistryOncology030220 oncology & carcinogenesisMED/06 - ONCOLOGIA MEDICAAdvanced breast cancermedicine.symptombusinessResearch Papermedicine.drug
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Physical Activity Level Following Resistance Training in Community-Dwelling Older Adults Receiving Home Care: Results from a Cluster-Randomized Contr…

2021

Older adults’ physical activity (PA) is low. We examined whether eight months of resistance training increased PA level in community-dwelling older adults receiving home care. A two-armed cluster-randomized trial using parallel groups was conducted. The included participants were &gt

medicine.medical_specialtyStrength trainingHealth Toxicology and MutagenesisBody weightelderlyArticlelaw.invention03 medical and health sciences0302 clinical medicineRandomized controlled trialInterquartile rangelawstrength trainingHumansMedicinephysical behaviorVDP::Medisinske Fag: 700030212 general & internal medicineAccelerometer dataAgedAged 80 and overindependent livingexercisebusiness.industryRPublic Health Environmental and Occupational HealthResistance trainingResistance Training030229 sport sciencesSedentary behaviorVDP::Medisinske Fag: 700::Idrettsmedisinske fag: 850Home Care ServicesPhysical activity levelPhysical therapyMedicineSedentary Behaviorbusiness
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Changes in health-related quality of life in elderly men after 12 weeks of strength training

2017

Background Muscular strength is associated with functional ability in elderly, and older adults are recommended to perform muscle-strengthening exercise. Understanding how improved muscle strength and -mass influence general and specific domains of quality of life is important when planning health promotion efforts targeting older adults. The aims of the present study were to describe changes in health-related quality of life (HRQOL) in older men participating in 12 weeks of systematic strength training, and to investigate whether improvements in muscle strength and muscle mass are associated with enhancements in HRQOL. Methods We recruited 49 men aged 60–81 years to participate in an inter…

medicine.medical_specialtyStrength trainingphysical activitylcsh:GeriatricsPhysical strengthelderly03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationSF-12Quality of lifemedicinestrength training030212 general & internal medicineFunctional abilityLeg pressbusiness.industryBiceps curl030229 sport sciencesTrunkHRQOLlcsh:RC952-954.6Physical therapyLean body massGeriatrics and GerontologybusinessResearch Article
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Use of Marginal Donors in Kidney Transplantation: Our Experience

2006

The use of elderly donors has been advocated to expand the organ donor pool because of increased needs and the organ shortage. The aim of this study was to analyze whether the use of elderly donors and marginal kidneys affected the outcome of renal transplantations. Herein we presented data on 126 kidney transplantations performed from January 1996 to September 2003 using 32 marginal donors (group A) and 94 ideal donors (group B). We analyzed the medical and surgical complications and the graft survivals at a median follow-up of 18 months. Medical and surgical complications occurred in 22% and 5% versus 7% and 4% in groups A and B, respectively. The mean cold ischemia time and the mean age …

medicine.medical_specialtyTime FactorsWaiting ListsEconomic shortageelderly patientsCold Ischemia TimeGroup BPostoperative ComplicationsCadaverHumansMedicineDonor poolKidney transplantationMarginal donorRetrospective StudiesTransplantationKidneybusiness.industryGraft SurvivalMean agemedicine.diseaseKidney TransplantationTissue DonorsSurgeryTreatment Outcomemedicine.anatomical_structureItalySurgeryGraft survivalbusinessFollow-Up StudiesTransplantation Proceedings
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Des lésions cutanées diffuses

2015

International audience

medicine.medical_specialty[ SDV.MHEP.GEG ] Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontologyNorwegian scabies030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineElderlyInternal MedicinemedicinePersonne âgéeImmunodepressionComputingMilieux_MISCELLANEOUS0303 health sciencesmedicine.diagnostic_test030306 microbiologybusiness.industry[SDV.MHEP.GEG]Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontologyGastroenterologymedicine.diseaseDermatologyGale norvégienneNorwegian scabiesPositron emission tomographySarcoidosisbusinessPanniculitis[ SDV.MHEP.DERM ] Life Sciences [q-bio]/Human health and pathology/Dermatology[SDV.MHEP.DERM]Life Sciences [q-bio]/Human health and pathology/Dermatology
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Diamond-Shaped Mini-Craniotomy: A New Concept in Neurosurgery

2021

Abstract Background We describe, step by step, a modified, less invasive, diamond-shaped mini-craniotomy that optimizes dural opening and can be performed in elderly patients affected by acute subdural or intracerebral hematomas, in therapy with antiplatelets or anticoagulants. Methods We retrospectively analyzed the clinical records of 67 patients (mean age of 78.5 years) treated in our institution, during a period of 10 years, with this novel diamond-shaped craniotomy. Seventeen patients were treated for intracerebral hemorrhage and 50 patients for acute subdural hematomas. All the patients were in therapy with antiplatelets or anticoagulants. Results Approach-related complications were n…

medicine.medical_specialtyanticoagulantsmedicine.medical_treatmentNeurosurgeryTemporal muscleelderlyacute subdural hematomaAtrophymedicineDeformityHematoma Subdural AcuteHumansGlasgow Coma ScaleCraniotomyAgedCerebral HemorrhageRetrospective StudiesIntracerebral hemorrhagePalsybusiness.industrycraniotomymedicine.diseaseintracerebral hemorrhageSurgerybody regionsTreatment Outcomemedicine.anatomical_structureScalpSurgeryNeurology (clinical)Neurosurgerymedicine.symptombusiness
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Adaptation and Refinement of Validated Risk Screening Tools in the Spanish Healthcare System

2013

Abstract The aim of this study is to develop a tool to screen elders at risk of hospital readmissions adapted to Spanish target population. The development of this new tool is based on the validated instrument The Community Assessment Risk Screen – CARS –, which is being applied in a sample of 1.000 older patients. The adaptation and refinement of CARS is being carried out through the compilation of new potential variables from primary care clinicians to predict patients at risk of readmissions. The introduction of this new instrument adapted to Spanish target population will provide a potential tool to identify prematurel y patients at risk of hospital readmissions.

medicine.medical_specialtybusiness.industryChronic PatientsSample (statistics)Primary careTarget populationmedicine.diseaseReadmissionsElderlyRisk screeningOlder patientsPhysical therapymedicineGeneral Materials ScienceScreening toolMedical emergencyScreening ToolsbusinessAdaptation (computer science)Healthcare systemProcedia - Social and Behavioral Sciences
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Trial on the Possibility to Assess the Static and Dynamic Balance in the Elderly with Diseases on the Level of the Supporting Joints

2019

The study aims to identify human walking disorders, proposing a model to solve these disorders, regardless of what caused them. Material and method Clinical and somatometric tests, pedometric investigations and sensors were used. An outpatient trial was conducted for a period of 6 weeks with a frequency of application of the recovery program of 3 times / week. For this study, there were 21 patients over the age of 65 years, which were divided into two groups: the witness group in which 11 patients had upper limb and / or spine disorders, and the control group with 10 patients with degenerative diseases in the knees and ankles. The tests were applied to both groups following the demographic …

medicine.medical_specialtybusiness.industryDemographic dataGait03 medical and health sciences0302 clinical medicinemedicine.anatomical_structurePhysical medicine and rehabilitationMedicineUpper limbData recording030212 general & internal medicinebusinessDynamic balanceElderly patient030217 neurology & neurosurgeryPelvisBalance (ability)2019 E-Health and Bioengineering Conference (EHB)
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Body Mass Index and Cardiac Events in Elderly Patients

2009

Body Mass Index has been challenged as an anthropometric measurement in elderly patients. Recent data, even in elderly patients, has demonstrated that elevated body mass index affords a worse long-term prognosis, although the magnitude of this relationship weakens as one ages. Underweight patients, possibly due to elements of sarcopenia and/or frailty, are also at a higher risk of overall mortality. A number of inflammatory mediators may be responsible for such factors which likely contribute to the increased risk of cardiovascular events observed. Although body mass index has been implicated in the development of heart failure, coronary artery disease and mediates its effects through other…

medicine.medical_specialtybusiness.industryOverweightmedicine.diseaseBMI Obesity elderly cardiovascular riskCoronary artery diseaseHeart failureInternal medicineSarcopeniamedicineLean body massCardiologyUnderweightmedicine.symptombusinessBody mass indexObesity paradox
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Community-onset Pseudomonas aeruginosa urinary sepsis in elderly people: Predictive factors, adequacy of empirical therapy and outcomes.

2019

Purpose To know the predictive factors for Pseudomonas aeruginosa (PA) urinary sepsis in hospitalised elderly patients coming from community, the adequacy of empirical antibiotic therapy and its outcomes. Methods Retrospective case-control study conducted between 2007 and 2017. Patients aged 65 years or older with PA urinary sepsis were included as cases. Three age-matched controls, with urinary sepsis caused by other microorganisms, were selected for each case. Predictors for PA urinary sepsis were determined by logistic regression analysis. Adequacy of empirical antibiotic therapy and outcomes were compared between both groups. Results A total of 332 patients, from which 83 were cases, we…

medicine.medical_specialtybusiness.industryPseudomonas aeruginosaUrinary systemGeneral Medicine030204 cardiovascular system & hematologymedicine.diseasemedicine.disease_causeLogistic regressionEmpirical antibiotic therapySepsis03 medical and health sciences0302 clinical medicineInternal medicinemedicineElderly people030212 general & internal medicinebusinessUrinary catheterCommunity onsetInternational journal of clinical practiceREFERENCES
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