Search results for "Election"

showing 10 items of 2159 documents

The 2015 Spanish election: the times they are a’ changing

2016

ABSTRACTThe Spanish legislative election of 2015 speaks of change. This is the end of the traditional two-party system and the beginning of a new political era marked by institutional renewal. The Socialist Party and the Partido Popular have both lost significant parliamentary force, whereas two new parties (Podemos, and Ciudadanos) are now crucial to ensure stable government majorities. This new parliamentary scenario seems to better mirror the political pluralism of a changing society which has already demonstrated for change in striking events such as the 15-M Movement. However, political parties are far from showing conciliatory aspirations, possibly because a new election is suddenly a…

021110 strategic defence & security studiesGovernment05 social sciencesGeography Planning and Development0211 other engineering and technologiesLegislatureContext (language use)02 engineering and technologyPublic administration0506 political sciencePoliticsPrimary electionPolitical Science and International Relations050602 political science & public administrationSociologyRegional & Federal Studies
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Economic globalisation, the perceived room to manoeuvre of national governments, and electoral participation: Evidence from the 2001 British General …

2016

Recent macro-level research argues that economic globalisation negatively affects electoral turnout by constraining the leeway of national governments and thereby rendering elections less meaningful to voters. This article analyses the link between perceptions of the national government's room to manoeuvre and turnout on the individual level. Drawing on the 2001 British General Election, it is shown that citizens who believe that economic globalisation leaves the national government with less influence on the economy are less likely to report to have voted. Further findings also support the proposed theoretical model according to which room to manoeuvre perceptions affect turnout via views …

021110 strategic defence & security studiesNational government05 social sciences0211 other engineering and technologiesTurnout02 engineering and technologyIndividual levelEconomic globalizationAffect (psychology)0506 political scienceScale (social sciences)Political economyPolitical scienceGeneral electionPolitical Science and International Relations050602 political science & public administrationVoter turnoutElectoral Studies
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“Save Romania” Union and the Persistent Populism in Romania

2020

The electoral success of the “Save Romania” Union (USR) in the 2016 parliamentary elections sheds new light on the rising populist parties in Romania and offers a new perspective on the Romanian po...

021110 strategic defence & security studiesSociology and Political ScienceRomanian05 social sciencesPerspective (graphical)0211 other engineering and technologies02 engineering and technologylanguage.human_language0506 political sciencePopulismPolitical economyPolitical scienceGeneral election050602 political science & public administrationlanguageProblems of Post-Communism
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A population genomics analysis of the native Irish Galway sheep breed.

2019

SUMMARYThe Galway sheep population is the only native Irish sheep breed and represents an important livestock genetic resource, which is currently categorised as “at-risk”. In the present study, comparative population genomics analyses of Galway sheep and other sheep populations of European origin were used to investigate the microevolution and recent genetic history of the breed. These analyses support the hypothesis that British Leicester sheep were used in the formation of the Galway breed and suggest more recent gene flow from the Suffolk sheep breed. When compared to conventional and endangered breeds, the Galway breed was intermediate in effective population size, genomic inbreeding a…

0301 basic medicine0106 biological sciencesAnimal breedingLivestocklcsh:QH426-470Populationbiology.animal_breedselection signaturePopulation geneticsZoologyinbreedingRuns of HomozygosityBiology010603 evolutionary biology01 natural sciencesGenetic diversityPopulation genomics03 medical and health sciences0302 clinical medicineEffective population sizesingle nucleotide polymorphismGeneticsInbreedingeducationGenetics (clinical)030304 developmental biologyOriginal Research2. Zero hunger0303 health scienceseducation.field_of_studybusiness.industryAt-risk breedat-risk breedgenetic diversitySelection signatureBreedSingle nucleotide polymorphismlivestocklcsh:Genetics030104 developmental biologyconservation genomics030220 oncology & carcinogenesisConservation genomicsSuffolk sheepMolecular MedicineLivestockFaculty of Science & Health AITbusinessInbreeding
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Cold adaptation drives population genomic divergence in the ecological specialist, Drosophila montana

2020

Funding: UK Natural Environment Research Council (Grant Number(s): NE/L501852/1, NE/P000592/1); Academy of Finland (GrantNumber(s): 267244, 268214, 322980), Ella ja Georg Ehrnroothin Säätiö. Detecting signatures of ecological adaptation in comparative genomics is challenging, but analysing population samples with characterised geographic distributions, such as clinal variation, can help identify genes showing covariation with important ecological variation. Here, we analysed patterns of geographic variation in the cold-adapted species Drosophila montana across phenotypes, genotypes and environmental conditions and tested for signatures of cold adaptation in population genomic divergence. We…

0301 basic medicine0106 biological sciencesCandidate geneEcological selectionQH301 Biology01 natural sciencesGenomeDivergencekylmänkestävyysChill coma recovery timeCCRTD. montanamuuntelu (biologia)sopeutuminen0303 health scienceseducation.field_of_studyGEMontanaEcologyGenomicsgenomiikkageneettinen muunteluCline populationsEnvironmental adaptationpopulaatiogenetiikkaDrosophilaGE Environmental SciencesmahlakärpäsetPopulationQH426 GeneticsBiologyCold tolerance010603 evolutionary biology03 medical and health sciencesQH301GeneticsAnimalseducationQH426Ecology Evolution Behavior and SystematicsCTmin030304 developmental biologyComparative genomicsWhole genome sequencingBayes TheoremDAS030104 developmental biologyGenetics PopulationGenomic divergenceMetagenomicsAdaptation
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Consequences of single-locus and tightly linked genomic architectures for evolutionary responses to environmental change

2020

AbstractGenetic and genomic architectures of traits under selection are key factors influencing evolutionary responses. Yet, knowledge of their impacts has been limited by a widespread assumption that most traits are controlled by unlinked polygenic architectures. Recent advances in genome sequencing and eco-evolutionary modelling are unlocking the potential for integrating genomic information into predictions of population responses to environmental change. Using eco-evolutionary simulations, we demonstrate that hypothetical single-locus control of a life history trait produces highly variable and unpredictable harvesting-induced evolution relative to the classically applied multi-locus mo…

0301 basic medicineAcademicSubjects/SCI011400106 biological sciencesLinkage disequilibriumMultifactorial Inheritanceevolutionary simulationEnvironmental changeGenetic LinkageJhered/401 natural sciencesGenetics (clinical)recombination rate0303 health scienceseducation.field_of_studystructural genomic variationInheritance (genetic algorithm)Adaptation PhysiologicalBiological Evolutionclimate changePerspectiveTraitympäristönmuutoksetBiotechnologyPopulationevoluutioEnvironmentBiology010603 evolutionary biologyLife history theory03 medical and health sciencesVDP::Matematikk og Naturvitenskap: 400::Basale biofag: 470GeneticsEvolutionary dynamicseducationMolecular BiologySelection (genetic algorithm)030304 developmental biologygeenitModels GeneticGenetic Driftilmastonmuutoksetgenetic architectureGenetic architectureEditor's Choice030104 developmental biologyEvolutionary biologyperimäGene-Environment InteractionAdaptationlinkage disequilibrium
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Stature and long-term labor market outcomes: Evidence using Mendelian randomization.

2017

We use the Young Finns Study (N = ∼2000) on the measured height linked to register-based long-term labor market outcomes. The data contain six age cohorts (ages 3, 6, 9, 12, 15 and 18, in 1980) with the average age of 31.7, in 2001, and with the female share of 54.7. We find that taller people earn higher earnings according to the ordinary least squares (OLS) estimation. The OLS models show that 10 cm of extra height is associated with 13% higher earnings. We use Mendelian randomization, with the genetic score as an instrumental variable (IV) for height to account for potential confounders that are related to socioeconomic background, early life conditions and parental investments, which ar…

0301 basic medicineAdultEmploymentMaleSocial ValuesEconomics Econometrics and Finance (miscellaneous)03 medical and health sciencesYoung Adult0302 clinical medicinestatureMendelian randomizationCovariateEconometricsEconomicsHumans030212 general & internal medicinePoint estimationPersonnel Selectionta512FinlandEstimationta511EarningsSalaries and Fringe BenefitsInstrumental variableConfoundingtyöllisyysheight premiumta3142Mendelian Randomization AnalysisBody Height030104 developmental biologykorkeus8. Economic growthOrdinary least squaresearningsDemographyheightEconomics and human biology
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Matching for the MICA-129 polymorphism is beneficial in unrelated hematopoietic stem cell transplantation.

2016

Major histocompatibility complex class I polypeptide-related sequence A (MICA) is a highly polymorphic ligand of the activating NKG2D receptor on natural killer (NK) cells, γδ-T cells, and NKT cells. MICA incompatibilities have been associated with an increased graft-versus-host disease (GVHD) incidence, and the MICA-129 (met/val) dimorphism has been shown to influence NKG2D signaling in unrelated hematopoietic stem cell transplantation (uHSCT). We investigated the effect of MICA matching on survival after uHSCT. We sequenced 2172 patients and their respective donors for MICA. All patients and donors were high-resolution HLA-typed and matched for 10/10 (n = 1379), 9/10 (n = 636), or 8/10 (n…

0301 basic medicineAdultMalemedicine.medical_specialtyAdolescentmedicine.medical_treatmentImmunologyHematopoietic stem cell transplantationHuman leukocyte antigenMajor histocompatibility complexBiochemistryGastroenterology03 medical and health sciencesYoung Adult0302 clinical medicineInternal medicinemedicineMinor histocompatibility antigenHumansAgedPolymorphism GeneticbiologyDonor selectionbusiness.industryHistocompatibility TestingHistocompatibility Antigens Class IHematopoietic Stem Cell TransplantationCell BiologyHematologyMiddle AgedNKG2DNatural killer T cellSurvival AnalysisTissue DonorsSurgeryTransplantationstomatognathic diseases030104 developmental biologyGenetic LociMultivariate Analysisbiology.proteinFemalebusiness030215 immunologyBlood
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Combination of metabolism measurement and a time-lapse system provides an embryo selection method based on oxygen uptake and chronology of cytokinesi…

2016

Objective To evaluate correlations between oxygen consumption (OC) measurements before and after embryo cytokinesis, observing OC during embryo cleavages and combining that information with morphokinetics to relate to implantation potential. Design Prospective cohort study. Setting University-affiliated private IVF unit. Patient(s) A total of 1,150 injected oocytes in 86 first oocyte donation cycles with embryo transfer on day 3. Intervention(s) None. Main Outcome Measurement(s) We analyzed the embryo OC and combined this data with the cytokinesis event, exact timing (in hours) of blastomeric cleavages, with the use of an incubator equipped with time-lapse videography, gathering a total of …

0301 basic medicineAdultmedicine.medical_specialtyanimal structuresTime FactorsAdolescentPregnancy RateCell SurvivalTransducersVideo RecordingBiologyTime-Lapse ImagingAndrologyEmbryo Culture Techniques03 medical and health sciencesYoung Adult0302 clinical medicinePredictive Value of TestsPregnancymedicineHumansEmbryo ImplantationProspective StudiesSperm Injections IntracytoplasmicCytokinesis030219 obstetrics & reproductive medicineMiniaturizationEmbryogenesisObstetrics and GynecologyEmbryoMetabolismEquipment DesignEmbryo TransferEmbryo MammalianEmbryo transferSurgeryOxygenPregnancy rate030104 developmental biologyTreatment OutcomeReproductive Medicineembryonic structuresFemaleSelection methodEnergy MetabolismEmbryo qualityCytokinesisFertility and sterility
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Interactive effects of aging and aerobic capacity on energy metabolism-related metabolites of serum, skeletal muscle, and white adipose tissue

2021

ABSTRACTAerobic capacity is a strong predictor of longevity. With aging, aerobic capacity decreases concomitantly with changes in whole body metabolism leading to increased disease risk. To address the role of aerobic capacity, aging and their interaction on metabolism, we utilized rat models of low and high intrinsic aerobic capacity (LCRs/HCRs) and assessed the metabolomics of serum, muscle, and white adipose tissue (WAT). We compared LCRs and HCRs at two time points: Young rats were sacrificed at 9 months, and old rats were sacrificed at 21 months. Targeted and semi-quantitative metabolomics analysis was performed on ultra-pressure Liquid Chromatography Tandem Mass Spectrometry (UPLC-MS)…

0301 basic medicineAgingWhite adipose tissue030204 cardiovascular system & hematologychemistry.chemical_compound0302 clinical medicineTandem Mass SpectrometryMetabolitesaineenvaihduntametabolitesALL-CAUSE MORTALITY2. Zero hungerchemistry.chemical_classification0303 health sciencesmetabolomicsAmino acidmedicine.anatomical_structureCARDIOVASCULAR-DISEASEOBESITYaerobinen suorituskykyOriginal ArticleCARDIORESPIRATORY FITNESSARTIFICIAL SELECTIONmedicine.medical_specialtyAdipose Tissue WhiteEXERCISErasva-aineenvaihdunta03 medical and health sciencesMetabolomicsFATNESSAerobic capacityInternal medicinemedicineAnimalsMetabolomicsBeta (finance)Muscle SkeletalAerobic capacity030304 developmental biologyAMINO-ACID-METABOLISMFatty acid metabolismagingSkeletal muscleLipid metabolismCardiorespiratory fitnessMetabolismRatsaerobic capacityikääntyminen030104 developmental biologyEndocrinologyPHYSICAL-ACTIVITYchemistryFUEL SELECTIONaineenvaihduntatuotteet3111 Biomedicinekoe-eläinmallitGeriatrics and GerontologyEnergy MetabolismChromatography Liquid
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