Search results for "Elimi"

showing 10 items of 283 documents

Exploring the Chemoselectivity towards Cysteine Arylation by Cyclometallated Au III Compounds: New Mechanistic Insights

2020

To gain more insight into the factors controlling the efficient cysteine arylation by cyclometalated Au(III) complexes, the reaction between selected gold compounds and different peptides was investigated by high‐resolution liquid chromatography electrospray ionization mass spectrometry (HR‐LC‐ESI‐MS). The deducted mechanisms of C–S cross‐coupling, also supported by density functional theory (DFT) and quantum mechanics/molecular mechanics (QM/MM) calculations, evidenced the key role of secondary peptidic gold binding sites in favouring the process of reductive elimination.

010405 organic chemistryChemistryElectrospray ionizationOrganic Chemistrycyclometallated gold complexes010402 general chemistryMass spectrometry01 natural sciencesBiochemistryCombinatorial chemistryMolecular mechanicsReductive elimination0104 chemical sciencesddc:cysteine arylationGold CompoundschemoselectivitySettore CHIM/03 - Chimica Generale E InorganicapeptidesMolecular MedicineDensity functional theoryChemoselectivityMolecular BiologyCysteinemass spectrometry
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High-resolution stimulated Raman spectroscopy and analysis of the nu2, nu5 and 2 nu6 bands of 34SF6

2006

9 p.Special Issue: Nineteenth Colloquium on High Resolution Molecular Spectroscopy, Salamanca 11–16 September 2005

010504 meteorology & atmospheric sciencesBiophysicsAnalytical chemistryHigh resolution01 natural sciencesPreliminary analysisREGIONsymbols.namesakeMOLECULES0103 physical sciencesMoleculeStimulated ramanPhysical and Theoretical ChemistrySpectroscopyMolecular BiologyNU(3) BANDEMISSIONS0105 earth and related environmental sciences[PHYS.PHYS.PHYS-AO-PH]Physics [physics]/Physics [physics]/Atmospheric and Oceanic Physics [physics.ao-ph]SPECTRUM010304 chemical physicsChemistryCOMBINATION BANDCondensed Matter Physics3. Good healthOctahedron[ PHYS.PHYS.PHYS-AO-PH ] Physics [physics]/Physics [physics]/Atmospheric and Oceanic Physics [physics.ao-ph]NON-CO2 GREENHOUSE GASESsymbolsRaman spectroscopySF6
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Evolutionary history and species delimitations:a case study of the hazel dormouse, Muscardinus avellanarius

2017

Robust identification of species and significant evolutionary units (ESUs) is essential to implement appropriate conservation strategies for endangered species. However, definitions of species or ESUs are numerous and sometimes controversial, which might lead to biased conclusions, with serious consequences for the management of endangered species. The hazel dormouse, an arboreal rodent of conservation concern throughout Europe is an ideal model species to investigate the relevance of species identification for conservation purposes. This species is a member of the Gliridae family, which is protected in Europe and seriously threatened in the northern part of its range. We assessed the exten…

0106 biological sciences0301 basic medicineSpecies complexRange (biology)Muscardinus avellanariusSettore BIO/05 - ZoologiaEndangered speciesZoologyMuscardinusBiology010603 evolutionary biology01 natural sciences03 medical and health sciencesEvolutionary historybiology.animalGeneticsSpecies delimitationDormouseEcology Evolution Behavior and SystematicsEvolutionary significant unitEvolutionary significant unitbiology.organism_classificationGenetic divergence030104 developmental biologyPhylogenetic PatternThreatened speciesKeywords Muscardinus avellanariu
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Exploring species-level taxonomy in the Cryptocephalus flavipes species complex (Coleoptera: Chrysomelidae)

2016

In insects, morphological species identification is often challenging. The discrimination of closely related species may be hampered when only subtle differences in phenotypic characters or a continuum in their variability are present. This is exemplified in the Cryptocephalus flavipes species complex (Coleoptera; Chrysomelidae) where, until now, the species have been discriminated only by the yellow pattern on frons, pronotum, and epipleurae. In the present study, the phylogeny of the C. flavipes species complex was resolved through a multi-locus sequence approach, and the inclusion in the group of the phenotypically similar Cryptocephalus quadripustulatus Gyllenhal, 1813 was evaluated. Su…

0106 biological sciences0301 basic medicineSpecies complexgeometric morphometricZoologyCryptocephalus quadripustulatus010603 evolutionary biology01 natural sciencesnew ISS rRNA PCR primers03 medical and health sciencesNew 18SrRNA PCR primerSpecies levelPhylogeneticsSpecies delimitationLeaf beetleDNA taxonomyEcology Evolution Behavior and SystematicsTaxonomybiologyBiodiversitybiology.organism_classificationCryptocephalus flavipes030104 developmental biologyTaxonspecies deliminationAnimal Science and ZoologyTaxonomy (biology)Leaf beetleZoological Journal of the Linnean Society
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Italian Odonates in the Pandora’s Box: A Comprehensive DNA Barcoding Inventory Shows Taxonomic Warnings at the Holarctic Scale

2020

AbstractThe Odonata are considered among the most endangered freshwater faunal taxa. Their DNA-based monitoring relies on validated reference datasets that are often lacking or do not cover important biogeographical centres of diversification. This study presents the results of a DNA barcoding campaign on Odonata, based on the standard 658 bp 5’ end region of the mitochondrial COI gene, involving the collection of 812 specimens (409 of which barcoded) from peninsular Italy and its main islands (328 localities), belonging to all the 88 species (31 Zygoptera and 57 Anisoptera) known from the country. Additional BOLD and GenBank data from Holarctic samples expanded the dataset to 1294 DNA barc…

0106 biological sciences0301 basic medicineSystematicsSpecies complexOdonataEndangered speciesBiologyOdonata010603 evolutionary biology01 natural sciencesDNA barcodingAnisoptera; BOLD; cryptic species; Odonata; species delimitation; ZygopteraEvolution Molecular03 medical and health sciencesHolarcticodonata italy barcode BOLD Cryptic speciesGeneticsAnimalsDNA Barcoding TaxonomicAnisopteraZygopteraEcology Evolution Behavior and SystematicsPhylogenycryptic speciesbiology.organism_classificationGenetic divergencespecies delimitation030104 developmental biologyTaxonHaplotypesItalyEvolutionary biologycryptic specieTaxonomy (biology)AnisopteraBOLDBiotechnology
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Formally described species woefully underrepresent phylogenetic diversity in the common lichen photobiont genus Trebouxia (Trebouxiophyceae, Chloroph…

2020

Lichens provide valuable systems for studying symbiotic interactions. In lichens, these interactions are frequently described in terms of availability, selectivity and specificity of the mycobionts and photobionts towards one another. The lichen-forming, green algal genus Trebouxia Puymaly is among the most widespread photobiont, associating with a broad range of lichen-forming fungi. To date, 29 species have been described, but studies consistently indicate that the vast majority of species-level lineages still lack formal description, and new, previously unrecognized lineages are frequently reported. To reappraise the diversity and the evolutionary relationships of species-level lineages …

0106 biological sciences0301 basic medicineTrebouxiaAlgaeLichensLichenBiologyHolobiont010603 evolutionary biology01 natural sciences03 medical and health sciencesstomatognathic systemSpecies SpecificityPhylogeneticsChlorophytaSpecies delimitationGeneticsAlgae; Biodiversity; Fungi; Holobiont; Multigene; Species delimitation; Symbiosis; Chlorophyta; Genetic Loci; Lichens; Species Specificity; Biodiversity; PhylogenySymbiosisLichenMolecular BiologyEcology Evolution Behavior and SystematicsPhylogenyGenetic diversityintegumentary systemTrebouxiophyceaeFungiBiodiversitybiology.organism_classificationHolobiontstomatognathic diseasesPhylogenetic diversity030104 developmental biologyEvolutionary biologyGenetic LociMultigeneTaxonomy (biology)SymbiosiMolecular phylogenetics and evolution
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Squamation and ecology of thelodonts

2017

Thelodonts are an enigmatic group of Paleozoic jawless vertebrates that have been well studied from taxonomical, biostratigraphic and paleogeographic points of view, although our knowledge of their ecology and mode of life is still scant. Their bodies were covered by micrometric scales whose morphology, histology and the developmental process are extremely similar to those of extant sharks. Based on these similarities and on the well-recognized relationship between squamation and ecology in sharks, here we explore the ecological diversity and lifestyles of thelodonts. For this we use classic morphometrics and discriminant analysis to characterize the squamation patterns of a significant num…

0106 biological sciencesMaleScale (anatomy)Species DelimitationSpeciationlcsh:Medicine01 natural sciencesDemersal zonelcsh:ScienceChondrichthyesMultidisciplinaryEcologyGeographyEcologyPhysicsFishesClassical MechanicsBiodiversityBiological EvolutionDragHabitatVertebratesPhysical SciencesAnimal FinsFemaleResearch Article010506 paleontologyEvolutionary ProcessesEcological MetricsImaging TechniquesEcology (disciplines)PaleontologiaFluid MechanicsBiologyResearch and Analysis Methods010603 evolutionary biologyContinuum MechanicsAnimalsParasitesEcosystem diversityEcosystemSwimming0105 earth and related environmental sciencesMorphometricsEvolutionary BiologyMorphometrylcsh:REcology and Environmental SciencesOrganismsBiology and Life SciencesPaleontologyPelagic zoneFluid DynamicsPaleoecologySharksEarth Scienceslcsh:QParasitologyPaleoecologyEctoparasitesPaleobiologyElasmobranchiiPLoS ONE
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Integrative taxonomy resolves species identities within the Macrobiotus pallarii complex (Eutardigrada: Macrobiotidae)

2021

AbstractThe taxonomy of many groups of meiofauna is challenging due to their low number of diagnostic morphological characters and their small body size. Therefore, with the advent of molecular techniques that provide a new source of traits, many cryptic species have started to be discovered. Tardigrades are not an exception, and many once thought to be cosmopolitan taxa are being found to be complexes of phenotypically similar species. Macrobiotus pallarii Maucci, 1954 was originally described in South Italy and has been subsequently recorded in Europe, America, and Asia. This allegedly wide geographic range suggests that multiple species may be hidden under this name. Moreover, recently, …

0106 biological sciencesSpecies complexkarhukaisetLineage (evolution)Population010607 zoologyBiology010603 evolutionary biology01 natural sciencesDNA barcodingcryptic taxaDNA barcodingspecies complexeducationnew specieseducation.field_of_studyPhylogenetic treePhylumsystematiikka (biologia)fylogenetiikkaDNAegg ornamentationspecies delimitationTaxonQL1-991Evolutionary biologyDNA-viivakooditlajinmääritysAnimal Science and ZoologyTaxonomy (biology)ZoologyResearch ArticleZoological Letters
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DNA barcoding of marine fishes from Saudi Arabian waters of the Gulf

2019

We used the cytochrome oxidase subunit I (coI) gene DNA to barcode 117 endemic Gulf and cosmopolitan Indo-West Pacific fish species belonging to 54 families and 13 orders. Novel DNA barcodes were provided for 18 fish species (Trachinocephalus sp., Nematalosa sp., Herklotsichthys lossei, Upeneus doriae, Trachurus indicus, Apogonichthyoides taeniatus, Verulux cypselurus, Favonigobius sp., Suezichthus gracilis, Sillago sp., Brachirus orientalis, Pegusa sp., Lepidotrigla bispinosa, Lepidotrigla sp., Grammoplites suppositus, Hippichthys sp., Paramonacanthus sp. and Triacanthus sp.). The species delimitation analysis, conducted with Poisson tree processes- Bayesian PTP (PTP-bPTP) and nucleotide-d…

0106 biological sciencesfood.ingredientSaudi ArabiaSettore BIO/05 - ZoologiaZoologyTrachinocephalusAquatic Science010603 evolutionary biology01 natural sciencesDNA barcodingElectron Transport Complex IVfoodAnimalsDNA Barcoding TaxonomicEcology Evolution Behavior and SystematicsPhylogenyHerklotsichthysSillagoLepidotriglabiology010604 marine biology & hydrobiologyFishesBayes TheoremBiodiversitySequence Analysis DNAmolecular species delimitationbiology.organism_classificationPriacanthidaeEphippidaeichtyofaunabiodiversity assessmentUpeneusIndo-Pacific Ocean
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Spectrum of mutations in Italian patients with familial hypercholesterolemia: New results from the LIPIGEN study

2017

Abstract Background Familial hypercholesterolemia (FH) is an autosomal dominant disease characterized by elevated plasma levels of LDL-cholesterol that confers an increased risk of premature atherosclerotic cardiovascular disease. Early identification and treatment of FH patients can improve prognosis and reduce the burden of cardiovascular mortality. Aim of this study was to perform the mutational analysis of FH patients identified through a collaboration of 20 Lipid Clinics in Italy (LIPIGEN Study). Methods We recruited 1592 individuals with a clinical diagnosis of definite or probable FH according to the Dutch Lipid Clinic Network criteria. We performed a parallel sequencing of the major…

0301 basic medicineApolipoprotein ECandidate geneSettore MED/09 - Medicina InternaDatabases FactualApolipoprotein BDNA Mutational AnalysisFamilial hypercholesterolemia030204 cardiovascular system & hematologyCompound heterozygosityPCSK90302 clinical medicineRisk FactorsReceptorsGeneticsHomozygoteAutosomal dominant traitPathogenic variantsGeneral MedicinePrognosisAPOB; Familial hypercholesterolemia; LDLR; PCSK9; Pathogenic variantsCholesterolPhenotypeItalyAutosomal Recessive HypercholesterolemiaApolipoprotein B-100lipids (amino acids peptides and proteins)Proprotein Convertase 9APOBCardiology and Cardiovascular MedicinePreliminary DataGenetic MarkersFamilial hypercholesterolemiaLDLRPCSK9APOBPathogenic variantsHeterozygoteFamilial hypercholesterolemiaBiologyPathogenic variantLDLHyperlipoproteinemia Type II03 medical and health sciencesDatabasesmedicineInternal MedicineHumansAPOB; Familial hypercholesterolemia; LDLR; Pathogenic variants; PCSK9; Internal Medicine; Cardiology and Cardiovascular MedicineGenetic Predisposition to DiseaseFactualPCSK9Settore MED/13 - ENDOCRINOLOGIAAPOB; Familial hypercholesterolemia; LDLR; Pathogenic variants; PCSK9; Cardiology and Cardiovascular Medicine; Internal Medicinemedicine.diseaseAtherosclerosis030104 developmental biologyLDLRReceptors LDLMutationbiology.proteinAPOB; Familial hypercholesterolemia; LDLR; Pathogenic variants; PCSK9; Apolipoprotein B-100; Atherosclerosis; Cholesterol; DNA Mutational Analysis; Databases Factual; Genetic Markers; Genetic Predisposition to Disease; Heterozygote; Homozygote; Humans; Hyperlipoproteinemia Type II; Italy; Phenotype; Preliminary Data; Prognosis; Proprotein Convertase 9; Receptors LDL; Risk Factors; Mutation; Internal Medicine; Cardiology and Cardiovascular Medicine
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