Search results for "Eliti"

Cannabinoids in the management of spasticity associated with multiple sclerosis.

2008

Anna Maria Malfitano, Maria Chiara Proto, Maurizio BifulcoDipartimento di Scienze Farmaceutiche, Università degli Studi di SalernoAbstract: The endocannabinoid system and cannabinoid-based treatments have been involved in a wide number of diseases. In particular, several studies suggest that cannabinoids and endocannabinoids may have a key role in the pathogenesis and therapy of multiple sclerosis (MS). In this study we highlight the main findings reported in literature about the relevance of cannabinoid drugs in the management and treatment of MS. An increasing body of evidence suggests that cannabinoids have beneficial effects on the symptoms of MS, including spasticity and pai…

Korpusavusteinen diskurssintutkimus (CADS): analyysiesimerkki homouden ja heterouden digitaalisista diskursseista

2018

The article aims at combining two methodological approaches, namely corpus linguistics and discourse studies. Both of these approaches are present in corpus-assisted discourse studies (CADS) which makes use of both quantitative and qualitative methodologies. First, an attempt is made to discuss the differences and similarities of these two traditions based on Leech’s (2000) listing. However, it turns out that this listing does not include all necessary viewpoints, and those are further discussed. In the empirical section of the paper, the Suomi24 corpus is analysed in order to provide an example of CADS. The analysis was carried out through collocation and discourse prosody analyses. The re…

Humoral Mechanisms in T cell Vaccination: Induction and Functional Characterization of Anti-lymphocytic Autoantibodies

1997

T cell vaccination, the application of syngeneic attenuated T cells, has been shown to prevent effectively and treat experimental autoimmune diseases, but its mechanisms of action are poorly understood. Here we present data on the induction of a humoral anti-T cell response by T cell vaccination, capable of strongly inhibiting T cell proliferation and of ameliorating experimental autoimmune disease. T cell vaccination in the Lewis rat induced autoantibodies reactive with several syngeneic T cell proteins. These autoantibodies were not detectable in normal Lewis sera as assessed by immunoblotting and flow cytometry with intact syngeneic T cells. The autoantibody reactivity was not restricted…

Review of 8 years of experience with Infanrix hexa (DTPa-HBV-IPV/Hib hexavalent vaccine).

2009

Combination vaccines that include multiple antigens within one formulation are now widely accepted as an effective means of eliciting protection against several diseases at the same time. Owing to improvements in quality and convenient modes of administration, they have become part of routine pediatric practice. Hexavalent vaccines, including diphtheria, tetanus, pertussis, hepatitis B, polio and Haemophilus influenzae type b antigens represent the latest advance in the development of combination vaccines. Over 8 years since its first licensure, this review looks at the immunogenicity, efficacy and safety profile of the only hexavalent pediatric vaccine currently in use--Infanrix hexa (diph…

Anders Wilhelm Ingman – kiistanalainen raamatunkääntäjä

2022

Diskurssintutkimus - monitieteinen ja monimenetelmäinen ala

2018

There is a growing interest towards metatheoretical examination of linguistic research. This special issue contributes to this examination from the perspective of discourse studies. The issue consists of seven articles which present methods in different areas of discourse studies. The aim of this introductory article is firstly to define the notions of discourse and method. Secondly, through the presentation of the articles of the issue, we present a variety of methods pertaining to different stages of research. In particular, methods of data collection and classification, as well as of data analysis, are presented. We conclude the article with some remarks on the future avenues of the meth…

Lisää taitoja ja mahdollisuuksia varhaiskasvatukseen: Tavoitteena tasa-arvoisempi ja kielitietoisempi varhaiskasvatus

2021

Kasvatuksellisen ja koulutuksellisen tasa-arvon toteutuminen monikielistyvässä Suomessa edellyttää entistä kielitietoisempaa varhaiskasvatusta (Puukko ym., 2019). Monikulttuurisuuden kohtaaminen on arvioitu yhdeksi keskeisimmäksi varhaiskasvatuksen tulevaisuuden osaamistaidoksi (Karila ym., 2013), ja monikielisyyden lisääntyminen haastaa ja kannustaa kehittämään entistä sensitiivisempiä, vuorovaikutuksellisia pedagogisia käytänteitä (Karila, 2016). Teimme keväällä 2017 verkkokyselyn, jonka tavoitteena oli kerätä tietoa ja näkökulmia monikielisyyden kohtaamisesta sekä kielitietoisista työskentelytavoista suomalaisessa varhaiskasvatuksessa. Kysely oli suunnattu monikielisessä lapsiryhmässä ty…

Étude comparative du futur simple dans un corpus littéraire finno-français

2008

Neural correlates of morphological processing and its development from pre-school to the first grade in children with and without familial risk for d…

2022

Previous studies have shown that the development of morphological awareness and reading skills are interlinked. However, most have focused on phonological awareness as a risk factor for dyslexia, although there is considerable diversity in the underlying causes of this reading difficulty. Specifically, the relationship between phonology, derivational morphology, and dyslexia in the Finnish language remains unclear. In the present study, we used magnetoencephalography (MEG) to measure the brain responses to correctly and incorrectly derived Finnish nouns in 34 first grade Finnish children (21 typically developing and 13 with familial risk for dyslexia). In addition, we compared longitudinall…

Transitivity prominence within and across modalities

2020

The idea of transitivity as a scalar phenomenon is well known (e.g., Hopper & Thompson 1980; Tsunoda 1985; Haspelmath 2015). However, as with most areas of linguistic study, it has been almost exclusively studied with a focus on spoken languages. A rare exception to this is Kimmelman (2016), who investigates transitivity in Russian Sign Language (RSL) on the basis of corpus data. Kimmelman attempts to establish a transitivity prominence hierarchy of RSL verbs, and compares this ranking to the verb meanings found in the ValPal database (Hartmann, Haspelmath & Bradley 2013). He arrives at the conclusion that using the frequency of overt objects in corpus data is a successful measure o…