Search results for "Enos"
showing 10 items of 1576 documents
Beta-3 adrenergic receptor overexpression reverses aortic stenosis-induced heart failure and restores balanced mitochondrial dynamics
2022
25 p.-7 fig.
USO DI UNA PROTESI BIORIASSORBIBILE IN PHEA-PLA-PCL PER IL CONFEZIONAMENTO DI FISTOLE ARTERO-VENOSE: STUDIO PRELIMINARE SU MODELLO SUINO
I traffici illeciti nel Mediterraneo. Persone, stupefacenti, tabacco
2019
Attraverso la combinazione di ricerca criminologica e giuridico-normativa, e grazie anche alla collaborazione con esperti esterni (studiosi, magistrati, rappresentanti di istituzioni italiane e straniere), la ricerca da cui scaturisce il volume ha indagato le interazioni tra i diversi traffici illeciti e la criminalità organizzata nel bacino del Mediterraneo. In tale area, storicamente cruciale per la mobilità di persone e di beni, l’attenzione si è rivolta in particolare ai fenomeni del traffico e della tratta di persone, del traffico di stupefacenti e del contrabbando di sigarette. I contributi raccolti – unitamente al rapporto criminologico e ai cinque rapporti nazionali accessibili su w…
Influence of environmental factors on small cetacean distribution in the Spanish Mediterranean
2008
Habitat distribution models are one of the most up to date methods to study the habitat usage of wildlife populations. They allow animal distribution to be related to environmental features and also the prediction of the distribution of animals based on this relationship. Seasonal aerial surveys were conducted in central Spanish Mediterranean waters from June 2000 to March 2003 to obtain information on the distribution of cetacean species. Data from the three most common cetacean species (striped dolphin,Stenella coeruleoalba, bottlenose dolphin,Tursiops truncatus, and Risso's dolphin,Grampus griseus) were related, using generalized linear models, to local environmental features: depth, slo…
Hadwenius tursionis (Marchi, 1873) n. comb. (Digenea, Campulidae) from the bottlenose dolphin Tursiops truncatus (Montagu, 1821) in the western Medit…
1994
The taxonomic position of Synthesium tursionis (Marchi, 1873) (Digenea, Campulidae) is revised, based on material from 147 worms from four bottlenose dolphins Tursiops truncatus stranded off the Comunidad Valenciana (Spanish western Mediterranean). The species is transferred to Hadwenius, as H. tursionis n. comb., and characterised by a high length/width ratio of the body, spinose cirrus and unarmed metraterm. Synthesium, a monotypic genus, becomes a synonym of Hadwenius. The intraspecific variation of some morphological traits is briefly discussed.
Mitochondrial dynamics in type 2 diabetes: Pathophysiological implications
2017
Mitochondria play a key role in maintaining cellular metabolic homeostasis. These organelles have a high plasticity and are involved in dynamic processes such as mitochondrial fusion and fission, mitophagy and mitochondrial biogenesis. Type 2 diabetes is characterised by mitochondrial dysfunction, high production of reactive oxygen species (ROS) and low levels of ATP. Mitochondrial fusion is modulated by different proteins, including mitofusin-1 (MFN1), mitofusin-2 (MFN2) and optic atrophy (OPA-1), while fission is controlled by mitochondrial fission 1 (FIS1), dynamin-related protein 1 (DRP1) and mitochondrial fission factor (MFF). PARKIN and (PTEN)-induced putative kinase 1 (PINK1) partici…
Suppression of inflammation by low-dose methotrexate is mediated by adenosine A2A receptor but not A3 receptor activation in thioglycollate-induced p…
2005
Prior studies demonstrate that adenosine, acting at one or more of its receptors, mediates the anti-inflammatory effects of methotrexate in animal models of both acute and chronic inflammation. Both adenosine A2A and A3 receptors contribute to the anti-inflammatory effects of methotrexate treatment in the air pouch model of inflammation, and the regulation of inflammation by these two receptors differs at the cellular level. Because different factors may regulate inflammation at different sites we examined the effect of low-dose weekly methotrexate treatment (0.75 mg/kg/week) in a model of acute peritoneal inflammation in adenosine A2A receptor knockout mice and A3 receptor knockout mice an…
Use of ATP bioluminescence for assessing the cleanliness of hospital surfaces: A review of the published literature (1990–2012)
2014
Summary: Hospital cleanliness tends to be considered by patients and the public as an important indicator of the general quality of healthcare. Tests for detecting the presence of adenosine triphosphate (ATP) as a proxy of microbial contamination are increasing in popularity, and several studies have been conducted on this topic in the last few decades. The aim of the present study was to review the published literature on this topic and summarize and discuss the available results. The review focused on relevant English-language articles that were identified through searches of two databases [PubMed and Scopus (1990–2012)] by using the keywords “ATP”, “bioluminescence”, “hospital”, and “sur…
Genetic structure of Triatoma venosa (Hemiptera: Reduviidae): molecular and morphometric evidence.
2006
Triatoma venosa presents a restricted geographical distribution in America and is considered as a secondary vector of Chagas disease in Colombia and Ecuador. A total of 120 adult insects were collected in domestic and peridomestic habitats in an endemic area of the department of Boyaca, Colombia, in order to determine their genetic structure through morphometric and molecular techniques. The head and wings of each specimen were used for the analyses of size, shape, and sexual dimorphism. A significant sexual dimorphism was found, although no differences in size among the studied groups were detected. Differences were found in the analyzed structures except for male heads. DNA was extracted …
Efavirenz alters mitochondrial respiratory function in cultured neuron and glial cell lines.
2015
Abstract Background The NNRTI efavirenz is among the most widely employed antiretroviral drugs. Although it is considered safe, efavirenz has been linked with several adverse effects including neurological manifestations, which appear in the majority of the patients on efavirenz-containing regimens. The molecular mechanisms responsible for these manifestations are not understood, but mounting evidence points to altered brain bioenergetics. Methods We evaluated the effect of short-term efavirenz treatment on the mitochondrial respiratory function of cultured glioblastoma and differentiated neuroblastoma cell lines using a Seahorse Extracellular Flux Analyzer. Results Incubation with efaviren…