Search results for "Envelope"
showing 10 items of 336 documents
Experimental evaluation of the durability of innovative cementitious coatings: photocatalytic activity and colour
2012
Today, in a world context characterized by high pollution levels and increasingly limited natural resources, even in the building sector, focusing on environmental issues, through energy saving and a more rational use of these resources, both during construction and management, is fundamental. An important contribution in this direction is given by the knowledge of the durability of products and building components, especially when innovative products are applied and no information are available on the reliability and service life. The research concerns the evaluation of the durability of cement-based photocatalytic coatings ("rasanti" in the Italian diction), containing different types of …
Curves with no tritangent planes in space and their convex envelopes
1990
M. H. Freedman ([3]) proved that for a generic subset of closed curves in ~ 3 with nonvanishing curvature and torsion the number of t r i tangent planes is even and finite. He also guessed, for each even number s _> 0, the existence of an open subset A8 of closed curves with nonvanishing curvature and torsion such tha t each curve in A8 has exact ly s t r i t angent planes. A question tha t can be asked in this context is: Which curves with nonvanishing curvature and torsion have no t r i tangent planes? An example of such a curve is given by the (1,2)-curve on the torus with rat io a, 3 < a < 5 (see [2]). For a generi c curve, we give a pa r t i a l answer to this question here by finding …
Scatter search for the profile minimization problem
2014
We study the problem of minimizing the profile of a graph and develop a solution method by following the tenets of scatter search. Our procedure exploits the network structure of the problem and includes strategies that produce a computationally efficient and agile search. Among several mechanisms, our search includes path relinking as the basis for combining solutions to generate new ones. The profile minimization problem PMP is NP-Hard and has relevant applications in numerical analysis techniques that rely on manipulating large sparse matrices. The problem was proposed in the early 1970s but the state-of-the-art does not include a method that could be considered powerful by today's compu…
Probing non-standard neutrino interactions with supernova neutrinos
2007
17 pages, 12 figures.-- PACS nrs.: 13.15.+g; 14.60.Lm; 14.60.St; 97.60.Bw.-- ISI Article Identifier: 000249786800015.-- ArXiv pre-print available at: http://arxiv.org/abs/0704.0032
Façade Solar Control and Shading Strategies for Buildings in the Mediterranean Region
2020
With the pressing need for holistic solutions that can help in overcoming the imminent environmental and resources crises, a call for the conservation of natural resources and sustainable strategies is needed. Sustainable strategies allow for the mitigation against the impact of climate change on the environment while, simultaneously, seeking the health and comfort of users. Another environmental issue that is worthy of the attention of the scientific research community is the reduction of resources consumption, through the implementation of sustainable development concepts and the use of renewable sources of energy generation. These two aforementioned paradigms are both intrinsic in nature…
Metabolism of Saccharomyces cerevisiae envelope mannoproteins.
1982
By pulse and chase labeling experiments, two independent mannoprotein pools have been found associated with the Saccharomyces cerevisiae envelope. One of them probably corresponds to mannoproteins localized in the periplasmic space. These molecules showed a high turnover rate at 28 degrees C. The second pool is formed by intrinsic wall mannoproteins which are apparently stable for long periods of time, after a small initial turnover. These results suggest that at least part of the mannoproteins initially found in the periplasmic space may move into the wall. The time lag between the addition of the radioactive precursors and their incorporation in the cell envelope (20-30 min for amino acid…
Evolutionary dynamics of the E1-E2 viral populations during combination therapy in non-responder patients chronically infected with hepatitis C virus…
2012
Abstract Half of the patients chronically infected with hepatitis C virus (HCV) genotype 1 fail to respond to pegylated interferon alpha (PEG-IFN) and ribavirin (RBV) therapy. This study assesses the effects of treatment on the evolution of the E1–E2 viral region in non-responder patients infected with HCV-1b. Twenty-three HCV-1b chronically infected patients were studied retrospectively, including 19 non-responders to PEG-IFN/RBV therapy (11 null-responders and 8 relapsers) in the study group, and 4 untreated patients in the control group. Genetic and phylogenetic analyses of the E1–E2 viral populations were performed at baseline and at the time of treatment failure to assess changes in ge…
The role of positive selection in hepatitis C virus
2008
Hepatitis C virus (HCV) is a major health problem worldwide, infecting an estimated 170 million people. In this study, we have employed a large data set of sequences (14,654 sequences from between 25 and 100 clone sequences per analyzed region and per patient) from 67 patients infected with HCV genotype 1 (23 subtype 1a and 44 subtype 1b). For all patients, a sample prior to combined therapy with alpha interferon plus ribavirin was available, whereas for some patients additional samples after 6 or 12 months of treatment were also available. Twenty-seven patients responded to treatment (12 subtype 1a and 15 subtype 1b) and forty patients did not respond to treatment (11 subtype 1a vs. 29 sub…
Using evolutionary tools to refine the new hypervariable region 3 within the envelope 2 protein of hepatitis C virus
2007
Abstract The envelope 2 protein of hepatitis C virus (HCV) presents three hypervariable regions, named HVR1, HVR2 and HVR3, in which the presence of antigenic sites has been described. Genetic variability in these regions may reflect the generation of escape mutants as a consequence of the immune response. Therefore, these regions would tend to accumulate amino acid changes along the infection process, an effect that could be accelerated by antiviral treatments. In this study, we have analyzed the E1–E2 region of 23 HCV patients non-responders to antiviral treatment, 7 of which were infected with subtype 1a, 15 with subtype 1b, and 1 with a new HCV-1 subtype, before and after 6 and/or 12 mo…
Molecular epidemiology of a hepatitis C virus outbreak in a hemodialysis unit.
2005
ABSTRACT We analyzed a hepatitis C virus (HCV) transmission case in the hemodialysis unit of a private clinic by sequencing two genome regions of virus isolates from a number of patients attending this unit and some external controls. The analysis of 337 nucleotides (nt) in the NS5B region did not provide enough resolution to ascertain which patients were actually involved in the outbreak and the potential source. Nevertheless, this region allowed the exclusion of several patients as putative sources of the transmission case based on their genotypes and phylogenetic relationships. On the other hand, the analysis of several 472-nt-long clone sequences per sample in a more rapidly evolving re…