Search results for "Envelope"

THE PERFORATED BUILDING’S ENVELOPE: GUIDING THE EARLY DESIGN PHASES

In passato gli involucri edilizi perforati sono stati talvolta ricondotti ad alcuni elementi architettonici tradizionali (come, ad esempio, la ‘Mashrabiyya’), in cui gli elementi forati acquisiscono quasi significati archetipici, nell’assumere ruoli tecnologici e ambientali che rispecchiano i valori della comunità, le condizioni socio-economiche e le esigenze ambientali degli occupanti. Oggi, invece, l’involucro edilizio perforato costituisce una tendenza architettonica che ha iniziato a manifestarsi a livello globale all’inizio del nuovo millennio, alla quale ha contribuito l’emergere della tecnologia digitale con i suoi effetti sull’innovazione di tecniche, materiali, realizzazioni, prest…

Crystal structure and absolute configuration of (4S,5R,6S)-4,5,6-trihydroxy-3-methylcyclohex-2-enone (gabosine H)

2017

The absolute configuration of the title compound, determined as 4S,5R,6S on the basis of the synthetic pathway, was confirmed by single-crystal X-ray diffraction. The mol­ecule is formed by a substituted six-membered cyclo­hexene ring adopting an envelope conformation and substituted by carbonyl, methyl and hydroxyl groups. The supra­molecular structure is mainly built by a combination of O—H⋯O and weaker C—H⋯O hydrogen bonds.

Sound Event Envelope Estimation in Polyphonic Mixtures

2019

Sound event detection is the task of identifying automatically the presence and temporal boundaries of sound events within an input audio stream. In the last years, deep learning methods have established themselves as the state-of-the-art approach for the task, using binary indicators during training to denote whether an event is active or inactive. However, such binary activity indicators do not fully describe the events, and estimating the envelope of the sounds could provide more precise modeling of their activity. This paper proposes to estimate the amplitude envelopes of target sound event classes in polyphonic mixtures. For training, we use the amplitude envelopes of the target sounds…

Performance Analyses of Innovative Glassblocks for BIPV

2014

The paper illustrates the results of the performance analyses conducted on an innovative glassblock integrated with 3rd generation dye-sensitized solar cells, designed for enabling the construction of translucent and sustainable building envelopes. The analyses encompass the simulation of both thermal and optical performance referring to different configurations of the PV-integrated glassblock, showing the results obtained by using two different software tools: Comsol Multiphysics and WINDOW. The configurations may differ, for example, because of the position of the module inside the glassblock, the type of dye-sensitized solar module used (composition, transparency, design), and glassblock…

Considerations about an indicator aimed at describing the energy efficiency of buildings with innovative envelope components at different climatic co…

2020

Green roofs are building components that have become increasingly common in urban contexts because other than the general improvement of the aesthetics of the buildings equipped with them, they have demonstrated to positively improve the building energy performance. Consequently, it would be useful for technicians to have easy and reliable indicators to achieve a synthetic quantitative judgement about the effectiveness of green roofs by an energy perspective compared to others building envelope technologies, for different climates. In sight of the definition of such an indicator, or at least of its properties, some considerations aimed at this purpose, especially concerning the use of new c…

Nuclear entry and egress of parvoviruses.

2022

Parvoviruses are small non-enveloped single-stranded DNA viruses, which depend on host cell nuclear transcriptional and replication machinery. After endosomal exposure of nuclear localization sequence and a phospholipase A2 domain on the capsid surface, and escape into the cytosol, parvovirus capsids enter the nucleus. Due to the small capsid diameter of 18–26 nm, intact capsids can potentially pass into the nucleus through nuclear pore complexes (NPCs). This might be facilitated by active nuclear import, but capsids may also follow an alternative entry pathway that includes activation of mitotic factors and local transient disruption of the nuclear envelope. The nuclear entry is followed b…

MIGLIORAMENTO TECNOLOGICO-PRESTAZIONALE DI UN COMPONENTE INNOVATIVO PER L’INVOLUCRO EDILIZIO - PERFOMANCE IMPROVEMENT OF AN INNOVATIVE BUILDING COMPO…

2016

L’articolo illustra l’attività di ricerca che gli autori, cofounder della SBskin. Smart Building Skin s.r.l., start up innovativa e spin off accademico dell’Università degli Studi di Palermo, stanno conducendo al fine di ottimizzare le performance energetiche di un componente innovativo per facciate e coperture di edifici (dagli stessi brevettato) in grado di ridurre i consumi energetici e di produrre energia pulita dal sole. L’attività che qui si illustra è stata finalizzata all’ottimizzazione del design dei sub-componenti che contribuiscono alla realizzazione dei pannelli traslucidi multifunzionali (realizzati con vetromattoni innovativi, preassemblati a secco e precompressi) ed alla scel…

Innovative, Translucent and Multi-functional Components for the Building Envelope: technological and performance optimization

2017

The paper describes the actions aimed at the technology and performance optimization of an innovative, multi-functional building component made of precast and pre-stressed glass blocks useful for the construction of sustainable building envelopes able to reduce the energy consumption and to produce clean energy from the sun. The design optimization of different sub-components and the choice of the right materials for guaranteeing their good response in terms of mechanical resistance, thermal and acoustic insulation, light transmission, electricity production, integration with other components, dimensional coordination, are particularly described.

Screening for inhibitors of HIV gp120-CD4 binding using an enzyme-linked immunoabsorbent assay.

1993

Binding of the HIV-1 major viral surface glycoprotein, gp120, to the major cell receptor, CD4, is essential for HIV infection of the target cell and syncytium formation. An enzyme-linked immunoassay using solid phase CD4 was used to quantitate the binding of HIV-1 gp120 to CD4, and to assess the activity and mechanism of action of putative inhibitors of that reaction. Monoclonal antibodies to the gp120 binding site on CD4 (e.g., Leu3a) blocked gp120 binding, while monoclonal antibodies to other portions of CD4 (e.g. OKT4) did not. Both aurintricarboxylic acid and sulfonated polysaccharides (e.g., dextran sulfate) blocked CD4-gp120 interactions by binding to the CD4 component. Human polyclon…

Age-dependent changes of nuclear envelope protein phosphokinase and protein phosphatase activities. Significance for altered nucleo-cytoplasmic mRNA …

1984

Nuclear envelopes are associated with a protein phosphokinase and a phosphoprotein phosphatase, whose activities are modulated by poly(A) in an opposite manner. The activities of these enzymes were determined in nuclear ghosts from liver and oviduct of quails of different age and of different hormone status. Under optimal conditions, kinase activity was found to increase in immature animals 8-fold in response to diethylstilbestrol; co-administration of progesterone had no marked effect on enzyme activity. After the initial burst, the activity of the enzyme increased only slightly during ageing. Two proteins present in nuclear ghosts of Mr 64 000 and of Mr 106 000 are phosphorylated during t…