Search results for "Envelope"
showing 10 items of 336 documents
Sulphoevernan, a polyanionic polysaccharide, and the narcissus lectin potently inhibit human immunodeficiency virus infection by binding to viral env…
1990
Sulphoevernan is a sulphated alpha-1----3, 1----4 polyglucan (Mr 20,000) with a helical structure. This compound effectively inhibits both human immunodeficiency virus type 1 (HIV-1) and type 2 infection of cells in vitro at concentrations around 0.5 micrograms/ml. Moreover, the compound completely inhibits HIV-1-induced syncytium formation at a concentration of 1 microgram/ml. Competition experiments with 35S-labelled sulphoevernan revealed that the mannose-specific lectin from Narcissus pseudonarcissus prevented binding of sulphoevernan to HIV-1, whereas the antibody OKT4A did not reduce the amount of sulphoevernan bound to MT-2 cells. These data indicate that the non-cytotoxic polymer su…
New Technologies for Adaptive Architecture
2019
Since the 1980s, the bioclimatic architecture has had the historical merit of having raised public and experts’ awareness on the importance of designing buildings with the purpose of solving the problem of energy saving. Nowadays, in the light of the most recent energy strategies policies, in force on an international and European scale, codified in EC Directive 31/2010 concerning the implementation of the Nearly Zer-Energy Buildings (NZEB), (Deru et al. 2006), the need for a new approach to redevelopment that focuses on environmental, climate and energy objectives with innovative technological solutions emerges, aimed at optimizing the passive bioclimatic behaviour of a building. In the wo…
Computing methods for resilience: evaluating new building components in the frame of SECAPs
2019
Resilience represents a new important feature that the anthropic systems, and cities among them, are called to cope with. In fact, the increasing negative stresses to which urban contexts are exposed, and mainly the climatic pressures, call for the capability of adapting to these modifications and, possibly, to restore the ex-ante situations. The role of the buildings and their envelope components is of crucial importance to this aim. This paper analyses the features of resilience of the roofs of buildings by means of proper quantitative indexes. On purpose, the performances of green and cool roofs are compared. The possibility of adopting nonstructural solutions, like the windows shading d…
Delay-Probability-Distribution-Dependent FIR Filtering Design with Envelope Constraints
2013
Published version of an article in the journal: Mathematical Problems in Engineering. Also available from the publisher at: http://dx.doi.org/10.1155/2013/930927 Open Access This paper studies the problem of H∞ finite-impulse response (FIR) filtering design of time-delay system. The time-delay considered here is time-varying meanwhile with a certain stochastic characteristic, and the probability of delay distribution is assumed to be known. Furthermore, the requirement of pulse-shape is also considered in filter design. Employing the information about the size and probability distribution of delay, a delay-probability-distribution-dependent criterion is proposed for the filtering error syst…
Astrophysics with the Laser Interferometer Space Antenna
2023
Full list of authors: Amaro-Seoane, Pau; Andrews, Jeff; Sedda, Manuel Arca; Askar, Abbas.; Baghi, Quentin; Balasov, Razvan; Bartos, Imre; Bavera, Simone S.; Bellovary, Jillian; Berry, Christopher P. L.; Berti, Emanuele; Bianchi, Stefano; Blecha, Laura; Blondin, Stephane; Bogdanovic, Tamara; Boissier, Samuel; Bonetti, Matteo; Bonoli, Silvia; Bortolas, Elisa; Breivik, Katelyn; Capelo, Pedro R.; Caramete, Laurentiu; Cattorini, Federico; Charisi, Maria; Chaty, Sylvain; Chen, Xian; Chruslinska, Martyna; Chua, Alvin J. K.; Church, Ross; Colpi, Monica; D'Orazio, Daniel; Danielski, Camilla; Davies, Melvyn B.; Dayal, Pratika; De Rosa, Alessandra; Derdzinski, Andrea; Destounis, Kyriakos; Dotti, Massi…
Categorization of Extremely Brief Auditory Stimuli: Domain-Specific or Domain-General Processes?
2011
The present study investigated the minimum amount of auditory stimulation that allows differentiation of spoken voices, instrumental music, and environmental sounds. Three new findings were reported. 1) All stimuli were categorized above chance level with 50 ms-segments. 2) When a peak-level normalization was applied, music and voices started to be accurately categorized with 20 ms-segments. When the root-mean-square (RMS) energy of the stimuli was equalized, voice stimuli were better recognized than music and environmental sounds. 3) Further psychoacoustical analyses suggest that the categorization of extremely brief auditory stimuli depends on the variability of their spectral envelope in…
Duck Hepatitis B Virus Requires Cholesterol for Endosomal Escape during Virus Entry
2008
ABSTRACT The identity and functionality of biological membranes are determined by cooperative interaction between their lipid and protein constituents. Cholesterol is an important structural lipid that modulates fluidity of biological membranes favoring the formation of detergent-resistant microdomains. In the present study, we evaluated the functional role of cholesterol and lipid rafts for entry of hepatitis B viruses into hepatocytes. We show that the duck hepatitis B virus (DHBV) attaches predominantly to detergent-soluble domains on the plasma membrane. Cholesterol depletion from host membranes and thus disruption of rafts does not affect DHBV infection. In contrast, depletion of chole…
Adaptive Materials Research for Architecture
2018
The volume "Adaptive Materials Research for Architecture" is a Special Issue of the journal "Advanced Material Research". The goal of this volume is to spread knowledge on studies, analyses and results of scientific research carried out from academics, researchers, and scientists regarding the soundest issues related to smart materials, innovative technologies and ongoing researches in the field of adaptive materials in past and current architectural practice.
DNA-mediated immunization to hepatitis B virus envelope proteins: preS antigen secretion enhances the humoral response.
1999
In order to design optimized DNA vectors as genetic vaccines against infections with the hepatitis B virus (HBV) we investigated if secretion or retention of the viral antigens has an influence on the quality and quantity of the humoral immune response. Intramuscular injection of plasmid DNA encoding the HBV large L envelope protein, known to be retained within host cells, induced only a weak response in mice whereas a vector expressing the secretion-competent small S envelope protein elicited strong and sustained immunity. Immunization with rearranged envelope genes further demonstrated that secretion affects the magnitude of the immune response. In situ expression of modified small and mi…
Membrane topology of gp41 and amyloid precursor protein: Interfering transmembrane interactions as potential targets for HIV and Alzheimer treatment
2009
AbstractThe amyloid precursor protein (APP), that plays a critical role in the development of senile plaques in Alzheimer disease (AD), and the gp41 envelope protein of the human immunodeficiency virus (HIV), the causative agent of the acquired immunodeficiency syndrome (AIDS), are single-spanning type-1 transmembrane (TM) glycoproteins with the ability to form homo-oligomers. In this review we describe similarities, both in structural terms and sequence determinants of their TM and juxtamembrane regions. The TM domains are essential not only for anchoring the proteins in membranes but also have functional roles. Both TM segments contain GxxxG motifs that drive TM associations within the li…