Search results for "Epidemiology"

showing 10 items of 4214 documents

Invasive meningococcal disease in Italy: from analysis of national data to an evidence-based vaccination strategy

2020

Introduction. Invasive meningococcal disease (IMD) is one of the most severe vaccine-preventable diseases not yet under control. In Italy, although different anti-meningococcal vaccines are available, their offer among regions is heterogeneous. The aim of this study is to describe the epidemiology of IMD in Italy based on analysis of national surveillance data for 2011–2017 to optimize the vaccination strategy. Methods: IMD surveillance data from the Italian National Health Institute were analysed. Microsoft Excel was used to present trend analysis, stratifying by age and serogroups. Results: In Italy, during the period 2011–2017, the incidence of IMD increased from 0.25 cases/100,000 inhab…

AdultAdolescentDatabases FactualInvasive meningococcal diseasesEpidemiologyMeningococcal VaccinesNO03 medical and health sciencesYoung AdultInvasive meningococcal diseases • epidemiology • surveillance system • anti-meningococcal vaccination strategiesHumansChildSurveillance system0303 health sciencesEvidence-Based Medicine030306 microbiologyInvasive meningococcal diseases Epidemiology Surveillance system Anti-meningococcal vaccination strategiesIncidenceInvasive meningococcal diseaseInfantMiddle AgedMeningococcal InfectionsItalyChild PreschoolPopulation SurveillanceOriginal ArticleAnti-meningococcal vaccination strategiesanti-meningococcal vaccination strategies.Journal of Preventive Medicine and Hygiene
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Antibodies to hepatitis B core antigen in blood donors screened for alanine aminotransferase level and hepatitis non-A, non-B in recipients.

1988

Four-hundred and seventeen patients undergoing open-heart surgery were followed for more than 9 months after transfusion. All 2270 blood units transfused had alanine aminotransferase levels less than or equal to 30 U/l. Blood units positive for antibodies to hepatitis B core antigen (anti-HBc) were more frequently associated with recipient hepatitis non-A, non-B (HNANB) (13.7%) than anti-HBc-negative units (4.2%) (p less than 0.001). The frequency of HNANB among recipients of at least 1 anti-HBc-positive blood unit (8/79, 10.1%) was fivefold greater than among recipients of exclusively anti-HBc-negative blood units (7/338, 2.1%) (p less than 0.01). In this study the exclusion of donors posi…

AdultAdolescentHepatitis Viral HumanImmunologyBlood DonorsAntigenImmunology and AllergyMedicineHumansAlanine aminotransferaseHepatitis B AntibodiesAgedHepatitisbiologybusiness.industryIncidence (epidemiology)virus diseasesTransfusion ReactionAlanine TransaminaseHematologyMiddle Agedmedicine.diseaseHepatitis B Core AntigensHepatitis Cdigestive system diseasesImmunologybiology.proteinBlood unitsAntibodybusinessDonor screeningHepatitis b coreTransfusion
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Allergen sensitizations in southern Italy: a 5-year retrospective study in allergic respiratory patients

2013

The assessment of the distribution of allergen skin test sensitizations is highly recommended for the optimal management of allergic respiratory conditions. We aimed at evaluating the distribution of allergen sensitizations in individuals with asthma and/or rhinitis in the Southern region of ltaly, and at exploring whether changes in the frequency of allergen sensitizations occurred after a 5-year period. Demographic data and skin prick test sensitizations to allergens from asthmatics and/or rhinitis attending the Division of Respiratory Diseases, University of Palermo, Italy in 2005 (Phase 1) and in 2010 (Phase 2) were extrapolated and retained for analysis. A total of 2033 allergic respir…

AdultAged 80 and overAdolescentItalyHypersensitivityPrevalenceHumansAllergensMiddle AgedChildAllergens/immunologyHypersensitivity/epidemiologyAgedRetrospective Studies
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Relationship of Flow Rate with Symptoms, Quality of Life and Other Clinical Parameters in Patients with LUTS Suggestive of BPH

2001

The uroflowmetry data of a selected number of patients who took part to the QUIBUS study (366 traces selected after quality control by a central panel of reviewer) were evaluated for their relationships with age, prostate volume, and IPSS and ICS-BPH scores. Waiting time, flow time, voided volume, maximum flow rate (Q(max)) and average flow rate (Q(ave)) were the flow variables considered for analysis. Only measurements with total voided volume exceeding 100 ml were included.An increasing percentage of subjects with voided volume200 ml was observed over 65 years of age. Age did not affect neither Q(ave) nor Q(max )(p = n.s. at correlation analysis). In particular, Q(max)was15 ml/s in about …

AdultAged 80 and overMaleGynecologymedicine.medical_specialtybusiness.industryUrologyProstatic HyperplasiaMiddle AgedUrination Disordersmedicine.diseaseUrodynamicsQuality of lifeLower urinary tract symptomsInternal medicineEpidemiologyQuality of LifemedicineHumansProstate diseaseProstatismIn patientbusinessAgedEuropean Urology
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Clinical-anamnestic and instrumental data in outpatients suffering from venous disease

1995

The authors studied 200 consecutive outpatients with symptoms due to venous disease of the lower limbs. All the patients underwent anamnestic, clinical and instrumental evaluation (c.w. Doppler velocimetry and strain-gauge plethysmography). The results of this study showed that some anamnestic and clinical data are significantly related to venous disease detected by instrumental techniques. The superficial and deep vein hypertension were, instead, correlated to oral contraceptive use.

AdultAged 80 and overMaleLegSettore MED/09 - Medicina InternaAdolescentMiddle AgedSettore MED/11 - Malattie Dell'Apparato CardiovascolarePlethysmographyAdolescent Adult Aged Aged 80 and over Blood Flow Velocity Contraceptives Oral/adverse effects Female Humans Hypertension/chemically induced Laser-Doppler Flowmetry Leg/blood supply Male Medical History Taking Middle Aged Morbidity Outpatients* Phlebitis/diagnosis Phlebitis/epidemiology Phlebitis/etiology* Plethysmography Pregnancy Retrospective Studies Risk FactorsPregnancyRisk FactorsHypertensionOutpatientsLaser-Doppler FlowmetryHumansFemaleMorbidityMedical History TakingPhlebitisBlood Flow VelocityAgedContraceptives OralRetrospective Studies
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Prevalence and distribution of oral mucosal non-malignant lesions in the western Sicilian population.

2016

BACKGROUNG: The aim of the present study was to determine the prevalence of oral mucosal non-malignant lesions in the Sicilian population. In addition, we evaluated the association between each oral lesion and its risk factors. METHODS: This study analyzed a total of 2539 consecutive patients, attending the Department of Surgical, Oncological and Stomatological Disciplines of Palermo University, who were examined for the presence of various oral lesions during the period from January 2012 and February 2015. RESULTS: The sample consisted of 1330 (52%) female and 1209 (48%) male. The age ranged from 13-86 years with a mean age of 47.16 years. Among these subjects 1495 (58%), presented one or …

AdultAged 80 and overMaleOutpatient Clinics HospitalAdolescentMouth MucosaMiddle AgedTongue DiseasesHospitals UniversityYoung AdultRisk FactorsPrevalenceHumansFemalemucous membranediseaseepidemiologyprevalenceitalyMouth DiseasesSicilyDiagnosis-Related GroupsAgedRetrospective StudiesMinerva stomatologica
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Management of Patients With Nonvariceal Upper Gastrointestinal Bleeding

2011

*Division of Gastroenterology, and Division of Clinical Epidemiology, McGill University and the McGill University Health Centre, Montreal, Quebec, Canada; INSERM IC-P 803, CHU du Bocage, Dijon, France; Universite de Bourgogne, Dijon, France; **Department of Medicine, Division of Gastroenterology, Farncombe Family igestive Health Research Institute, McMaster University, Hamilton, Ontario, Canada; Guelph General Hospital, Guelph and McMaster University, Guelph, Ontario, Division of Gastroenterology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; Division of Gastroenterology, Medical University Canada; f South Carlolina, Charleston, South Carolina; and the Departmen…

AdultAged 80 and overMaleSouth carolinamedicine.medical_specialtyHepatologybusiness.industryGastroenterologyClinical epidemiologyMiddle Agedmedicine.diseaseHealth centreSurgeryFamily medicinemedicineHumansFemaleUpper gastrointestinal bleedingGeneral hospitalGastrointestinal HemorrhagebusinessAgedClinical Gastroenterology and Hepatology
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Sister-chromatid exchange in cultured lymphocytes of ewes and their newborn lambs

1984

The incidence of sister-chromatid exchange (SCE) in cultured lymphocytes of ewes and their newborn lambs was determined using the BrdU-Giemsa technique. In all ewe-lamb pairs, the SCE rate in the lambs was less than that of the ewes. The mean SCE frequencies per chromosome of the ewes after lambing and of the newborn lambs were 0.1909 and 0.1581, respectively. The statistical analysis shows that a significant difference exists between SCE in the adult female sheep and their lambs. At the same time, a negative correlation was observed between SCE rate and cell proliferation. The results of this study are compared with those of previous reports on age-dependency of SCE.

AdultAgingAdolescentanimal diseasesSister chromatid exchangeBiologyAndrologyPregnancyparasitic diseasesAnimalsHumansStatistical analysisCrossing Over GeneticLymphocytesChildCells CulturedAgedGeneticsSheepAdult femaleIncidence (epidemiology)Domestic sheep reproductionSignificant differenceInfant NewbornInfantChromosomeGeneral MedicineMiddle Agedrespiratory systemAnimals NewbornChild PreschoolFemaleNegative correlationSister Chromatid ExchangeCell DivisionMutation Research Letters
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Survival in rhino-orbito-cerebral mucormycosis: An international, multicenter ID-IRI study

2022

International audience; BACKGROUND: Mucormycosis is an emerging aggressive mold infection. This study aimed to assess the outcome of hospitalized adults with rhino-orbito-cerebral mucormycosis (ROCM). The secondary objective was to identify prognostic factors in this setting. METHODS: This study was an international, retrospective, multicenter study. Patients’ data were collected from 29 referral centers in 6 countries. All qualified as "proven cases" according to the EORTC/MSGERC criteria. RESULTS: We included 74 consecutive adult patients hospitalized with ROCM. Rhino-orbito-cerebral type infection was the most common presentation (n = 43; 58.1%) followed by rhino-orbital type (…

AdultAntifungal AgentsSurveillanceNeutropeniaEpidemiologyMucormycosiInfectionsHospital-acquired infectionRhino-orbito-cerebral mucormycosisZygomycosis[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyDebridementRisk FactorsDiagnosisOrbital DiseasesRisk Factors.Internal MedicineHumansMucormycosisRhino-orbito-cerebral mucormycosiEye Infections FungalRetrospective Studies
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[Prevalence of pericardial effusion in subjects with rheumatoid arthritis: an echocardiographic study].

1994

We used echocardiography to determine the prevalence of pericardial effusion in rheumatoid arthritis (RA) patients without cardiac systems and compared our results to those obtained in a control group of age-matched subjects. Thirty-six patients with RA (6 men, 30 women; mean age 51 +/- 11 years) were selected from a patient population in treatment at our outpatient Rheumatology Clinic. None of the patients had any symptoms of cardiac disease, and all patients with signs and/or systems of extracardiac disease were excluded from the study. The control group consisted of 60 volunteers (mean age 51 +/- 12 years) randomly selected from a larger group of subjects with neither symptoms, signs and…

AdultArthritis RheumatoidMaleAdult Arthritis Rheumatoid/complications* Cross-Sectional Studies Echocardiography* Female Humans Male Middle Aged Pericardial Effusion/diagnosis Pericardial Effusion/epidemiology* Pericardial Effusion/etiology Time FactorsSettore MED/09 - Medicina InternaCross-Sectional StudiesTime FactorsEchocardiographyHumansFemaleMiddle AgedSettore MED/11 - Malattie Dell'Apparato CardiovascolarePericardial EffusionAnnali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna
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