Search results for "Epidemiology"
showing 10 items of 4214 documents
Does the “Silver Bullet” Lose its Shine Over the Time? Assessment of Loss of Lithium Response in a Preliminary Sample of Bipolar Disorder Outpatients.
2016
Background:Though often perceived as a “silver bullet” treatment for bipolar disorder (BD), lithium has seldom reported to lose its efficacy over the time.Objective:The aim of the present study was to assess cases of refractoriness toward restarted lithium in BD patients who failed to preserve maintenance.Method:Treatment trajectories associated with re-instituted lithium following loss of achieved lithium-based maintenance in BD were retrospectively reviewed for 37 BD-I patients (median age 52 years; F:M=17:20 or 46% of the total) over an 8.1-month period on average.Results:In our sample only 4 cases (roughly 11% of the total, of whom F:M=2:2) developed refractoriness towards lithium after…
987 Emipediology and Morbidity of Late Preterm Neonates in Correlation with Maternal Risk Factors in Hessen, Germany
2012
Short and long term morbidity in late preterm neonates (LP) and their correlation to maternal risk factors are relevant as shown in multiple studies in North America and European countries. Epidemiological studies showed an increase in LP birth over time. Corresponding data for Germany have not yet been published. Our goal was to evaluate the epidemiology of LP over a 7 year period and the correlation to potential maternal risk factors in Hessen, Germany. Data was collected from the perinatal und neonatal quality assurance in Hessen form 2001 to 2007. For some calculations the two data sets were merged. Overall the data sets of 360.000 births and 44.000 neonatal hospitalizations were availa…
Recent epidemiological studies on ionizing radiation and childhood cancer in Germany.
1998
The results from recent epidemiological studies based on the German Childhood Cancer Registry are summarized.An oecological study covers 16 years' incidence of childhood malignancies in areas surrounding nuclear facilities and in matched control regions. Two population-based case control studies explore potential risk factors of childhood leukaemia in the state of Lower Saxony (1988 93) and in all western states of Germany (1992-94).There was no increased incidence of childhood leukaemia and other malignancies in the vicinity of nuclear installations. X-ray examinations during pregnancy and in early childhood were not associated with an increased risk of childhood leukaemia. There were no d…
Stroke incidence and survival in three Sicilian municipalities
1998
We investigated the incidence of first-ever stroke in three Sicilian municipalities over the years 1984–1987. Case ascertainment involved two approaches: a doorto-door two-phase prevalence survey and a study of death certificates. Only first-ever strokes occurring within the study time interval were included, and diagnoses were based on specified criteria. We found 138 subjects who had experienced a first stroke over 73 488 person-years; the average incidence rate (new cases per 1000 population per year) was 1.9 overall, 1.7 in men, and 2.1 in women. Incidence increased steeply with age and was similar in men and women. Incidence was similar in the three study municipalities. The overall ca…
Epidemiological study of Italian patients with Fabry disease.
2007
Rotavirus gastroenteritis: epidemiological, clinical, therapeutic aspects and economic implications
2013
Results 114 cases were diagnosed with rotavirus gastroenteritis in 2011 and 122 cases in 2012, frequently in the colder months, sex ratio M/F 1.42/1 in 2011, 1.18/1 in 2012 and in the age group 1-3 (58.90% of cases). The clinical severity was assessed by Vesikari score: 91 cases admitted in 2011 (79.82%) and 112 cases admitted in 2012 (91.80%) presenting a medium/severe score. 15 cases presented neurological symptoms and also 15 cases had renal failure. Among the electrolyte disorders the most commonly found was hyponatremia ( 150mEq/L). The hospitalization costs of rotavirus gastroenteritis cases ranged from 58.60€ to 5345 RON (1243.02€).
Prenatal diagnosis and epidemiology of multicystic kidney dysplasia in Europe
2014
ObjectivesThe aim of this study is to describe the prenatal diagnosis and epidemiology of multicystic kidney dysplasia (MCKD). MethodsThe study is based on routinely collected data from a European database of major congenital anomalies including 13 registries with cases born in 1997-2006 and covering 1458552 births. ResultsThere were 601 MCKD cases giving an overall prevalence of 4.12 per 10000 births with regional variation. In live births, 87% of cases had an isolated renal anomaly and 13% had associated major nonrenal anomalies (chromosomal, syndrome or other major anomalies). For the cases with isolated renal anomalies, 51/386 (11%) and 7/386 (2%) choose to terminate the pregnancy or re…
Eine vergleichende Untersuchung zum Reizdarmsyndrom bei konsekutiven Patienten zweier internistischer Ambulanzen
2001
OBJECTIVES We investigated the nature of illness behavior and the meaning of emotional deficiencies during childhood in patients with irritable bowel diseases (IBS). DATA A consecutive study in two tertiary referral centers was conducted with 48 patients suffering from irritable bowel diseases (IBS) and 91 patients with inflammatory bowel disease (IBD). METHODS The diagnosis of IBS was made by following the Manning criteria, a positive diagnosis of IBD was established through physical, endoscopic and radiologic examinations and was confirmed histologically. Psychological data were obtained by structured psychiatric interviews and psychological self-report measures (GBB). RESULTS We found th…
Best practices, challenges and innovations in pediatrics in 2019
2020
AbstractThis paper runs through key progresses in epidemiology, pathomechanisms and therapy of various diseases in children that were issued in the Italian Journal of Pediatrics at the end of last year. Novel research and documents that explore areas such as allergy, critical care, endocrinology, gastroenterology, infectious diseases, neonatology, neurology, nutrition, and respiratory tract illnesses in children have been reported. These observations will help to control childhood illnesses.