Search results for "Equipment Design"

showing 10 items of 409 documents

Composite nanoparticles based on hyaluronic acid chemically cross-linked with alpha,beta-polyaspartylhydrazide.

2007

In this paper, new composite nanoparticles based on hyaluronic acid (HA) chemically cross-linked with alpha,beta polyaspartylhydrazide (PAHy) were prepared by the use of a reversed-phase microemulsion technique. HA-PAHy nanoparticles were characterized by FT-IR spectroscopy, confirming the occurrence of the chemical cross-linking, dimensional analysis, and transmission electron micrography, showing a sub-micrometer size and spherical shape. Zeta potential measurements demonstrated the presence of HA on the nanoparticle surface. A remarkable affinity of the obtained nanoparticles toward aqueous media that simulate some biological fluids was found. Stability studies showed the absence of chem…

Polymers and PlasticsBiocompatibilityCell SurvivalNanoparticleBioengineeringAntineoplastic AgentsPolymeric nanoparticles hyaluronic acid polyaminoacidBiomaterialschemistry.chemical_compoundDrug Delivery SystemsMicroscopy Electron TransmissionPolymer chemistryHyaluronic acidSpectroscopy Fourier Transform InfraredMaterials ChemistryZeta potentialHumansMicroemulsionHyaluronic AcidParticle SizeChemical decompositionChemistryHydrolysisEquipment DesignNylonsCross-Linking ReagentsHydrazinesChemical engineeringNanoparticlesFluorouracilDrug carrierK562 CellsNanogelBiomacromolecules
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Facial masks in children: the position statement of the Italian pediatric society

2020

AbstractFacial masks may be one of the most cost-effective strategies to prevent the diffusion of COVID 19 infection. Nevertheless, fake news are spreading, alerting parents on dangerous side effects in children, such as hypercapnia, hypoxia, gut dysbiosis and immune system weakness. Aim of the Italian Pediatric Society statement is to face misconception towards the use of face masks and to spread scientific trustable information.

Position statementWeakness2019-20 coronavirus outbreakmedicine.medical_specialtyConsensusCoronavirus disease 2019 (COVID-19)Pneumonia ViralFake newBetacoronavirus03 medical and health sciences0302 clinical medicineFacial mask030225 pediatricsDisease Transmission InfectiousmedicineHumansInfection control030212 general & internal medicinePsychiatryChildPandemicsChildrenCOVIDInfection ControlMaskPandemicBetacoronaviruSARS-CoV-2business.industryCoronavirus InfectionMaskslcsh:RJ1-570COVID-19lcsh:PediatricsEquipment DesignSettore MED/38Face masksDisease Transmission InfectiouFake newsCommentaryGut dysbiosisFake newsmedicine.symptomCoronavirus InfectionsbusinessHumanItalian Journal of Pediatrics
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Technical characteristics can make the difference in a surgical linear stapler. Or not?

2015

Background Anastomotic leak (AL) after gastrointestinal surgery is a severe complication associated with relevant short- and long-term sequelae. Most of the anastomosis are currently performed with a surgical stapler that is required to have appropriate characteristics to guarantee good performances. The aim of our study was to evaluate, in the laboratory, pressure resistance and tensile strength of anastomosis performed with different surgical linear staplers, available in the market. Materials and methods We have been studying three linear staplers, with diverse cartridges and staple heights, of three different companies, used for gastrointestinal anastomosis and gastric or intestinal clo…

Pressure resistancemedicine.medical_specialtyLeakPressure resistance; Surgical linear stapler; Surgical stapler; Tensile strength; Anastomosis Surgical; Anastomotic Leak; Animals; Biomechanical Phenomena; Equipment Design; Intestines; Pressure; Surgical Stapling; Swine; Tensile Strength; Surgical Staplers; Surgery; Medicine (all)AnastomosisSwineMean pressureAnastomotic LeakAnastomosisSurgical StaplersSurgicalTensile StrengthUltimate tensile strengthSurgical StaplingmedicinePressureAnimalsSevere complicationSurgical Staplerbusiness.industryAnimalMedicine (all)Anastomosis SurgicalPig intestineSurgical linear staplerEquipment DesignSurgeryIntestineBiomechanical PhenomenaIntestinesStaple lineSurgeryPressure resistancebusinessThe Journal of surgical research
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A New Configuration for Helmet Continuous Positive Airway Pressure Allowing Tidal Volume Monitoring

2020

We performed a bench and human study to test the hypothesis that a ventilator can accurately estimate Vt when a helmet is used in CPAP mode in a single limb configuration with an intentional leak port placed at the helmet expiratory port. We have recently demonstrated the effectiveness of this setup in bilevel mode

Pulmonary and Respiratory MedicineAdultMalemedicine.medical_specialtyTidal volume monitoringContinuous Positive Airway Pressurebusiness.industrymedicine.medical_treatmentEquipment DesignCritical Care and Intensive Care MedicineInternal medicineCardiologymedicineTidal VolumeHumansFemaleContinuous positive airway pressurebusinessNIV CPAP Acute respiratory failureMonitoring Physiologic
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Low-energy epicardial pacing in children: the benefit of autocapture.

1999

Abstract Background . Permanent cardiac pacing in children results commonly in augmented energy consumption because of the high pacing rates and the ample stimulation safety margin applied in children. Cardiovascular anatomy and limited venous access sometimes preclude the otherwise preferred endocardial approach. In this multicenter patient series, we studied the feasibility, safety, and energy saving obtained by a combination of steroid-eluting epicardial leads with autocapture devices capable of ongoing adjustment of the stimulation output to the prevailing threshold. Methods . Autocapture devices (Pacesetter Microny SR+ and Regency SR+; Pacesetter, Solna, Sweden) and steroid-eluting epi…

Pulmonary and Respiratory MedicineMalemedicine.medical_specialtyPacemaker ArtificialCardiac pacingEpicardial pacingSafety marginElectrocardiographyLow energyElectric Power SuppliesMicrocomputersInternal medicinemedicineHumansChildmedicine.diagnostic_testLife spanbusiness.industryInfantSignal Processing Computer-AssistedEquipment DesignVenous accessSurgeryElectrodes ImplantedEquipment Failure AnalysisChild PreschoolCardiologyFeasibility StudiesSurgeryFemaleCardiology and Cardiovascular MedicinebusinessElectrocardiographyPericardiumSoftwareEndocardiumThe Annals of thoracic surgery
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Intraoperative cryoablation of atrial fibrillation with the old-fashioned cryode tips: a simple, effective, and inexpensive method.

2006

Nowadays atrial fibrillation is usually treated simultaneously with cardiac procedures, and new cryo-systems have been developed for performing easier and faster intraoperative ablation. However, the old cryode designs can still be useful in surgical practice and represent a more cost-effective method. In this article we present a technique using old-fashioned cryodes for intraoperative treatment of atrial fibrillation and comment on its advantages and limitations.

Pulmonary and Respiratory MedicineMalemedicine.medical_specialtymedicine.medical_treatmentCost-Benefit AnalysisCatheter ablationmacromolecular substancesCryosurgeryRisk AssessmentCryosurgerySurgical EquipmentCardiac proceduresAtrial FibrillationmedicineSurgical equipmentHumansRetrospective StudiesIntraoperative Carebusiness.industryFollow up studiesCryoablationAtrial fibrillationEquipment DesignAblationmedicine.diseaseSurgeryTreatment OutcomeCatheter AblationSurgeryFemaleCardiology and Cardiovascular MedicinebusinessFollow-Up StudiesThe Annals of thoracic surgery
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Material and Technology: Back to the Future for the Choice of Interface for Non-Invasive Ventilation – A Concise Review

2020

Non-invasive ventilation (NIV) has dramatically changed the treatment of both acute and chronic respiratory failure in the last 2 decades. The success of NIV is correlated to the application of the “best ingredients” of a patient’s “tailored recipe,” including the appropriate choice of the selected candidate, the ventilator setting, the interface, the expertise of the team, and the education of the caregiver. The choice of the interface is crucial for the success of NIV. Type (oral, nasal, nasal pillows, oronasal, hybrid mask, helmet), size, design, material and headgears may affect the patient’s comfort with respect to many aspects, such as air leaks, claustrophobia, skin erythema, eye irr…

Pulmonary and Respiratory MedicineRespiratory failure.medicine.medical_specialtySkin erythemamedicine.medical_treatmentInterface (computing)Skin breakdownlaw.invention03 medical and health sciencesFacial deformity0302 clinical medicinelawHumansMedicine030212 general & internal medicineIntensive care medicineReduction (orthopedic surgery)Noninvasive VentilationContinuous Positive Airway Pressurebusiness.industryMasksEquipment DesignHome ventilationInterfacemedicine.diseaseHome setting030228 respiratory systemVentilation (architecture)Non-invasive ventilationClaustrophobiaRespiratory Insufficiencybusiness
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The da Vinci Xi Robotic Four-Arm Approach for Robotic-Assisted Minimally Invasive Esophagectomy

2018

AbstractRobotic surgery is gaining importance in complex thoracoscopic surgery, such as robotic-assisted minimally invasive esophagectomy (RAMIE). The RAMIE procedure was designed using the first generation of the robotic system. The latest da Vinci Xi system has substantially increased the dexterity, especially designed for multiquadrant surgery. The original three-arm RAMIE approach was modified including the robotic four-arm use for the thoracoscopic and laparoscopic part of the operation. This extended approach (four-arm RAMIE approach) provides more flexibility and raises the independence of the surgeon.

Pulmonary and Respiratory Medicinemedicine.medical_specialtyRobotic assistedTreatment outcomePatient positioningPatient Positioning03 medical and health sciencesEsophagus0302 clinical medicineRobotic Surgical ProceduresInvasive esophagectomymedicineHumansRobotic surgerybusiness.industryThoracoscopyEquipment DesignFirst generationSurgeryEsophagectomyTreatment OutcomeEsophagus surgeryRobotic systems030220 oncology & carcinogenesisLaparoscopy030211 gastroenterology & hepatologySurgeryCardiology and Cardiovascular MedicinebusinessThe Thoracic and Cardiovascular Surgeon
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Ventilator Settings to Avoid Nuisance Alarms During Mouthpiece Ventilation

2016

BACKGROUND: A recent study found that activation of disconnection and low-pressure alarms is common during mouthpiece ventilation and may represent a major limitation to its use. The aim of this bench study was: (1) to investigate the technical aspects that can influence the setting of the ventilator during mouthpiece ventilation and (2) to provide a practical setting strategy to avoid the alarm activation. METHODS: Eight life-support ventilators able to deliver volume controlled ventilation were tested in a bench study using a single-limb non-vented circuit configuration connected to a standard mouthpiece. Disconnection and apnea alarm were turned off or set at the least sensitive setting.…

Pulmonary and Respiratory Medicinemedicine.medical_treatmentCritical Care and Intensive Care Medicine03 medical and health sciencesALARMMechanical ventilation0302 clinical medicineTidal VolumemedicineVentilator settingsHumansChronic respiratory failureChronic respiratory failure; Mechanical ventilation; Mechanical ventilators; Neuromuscular disease; Noninvasive ventilation; Pulmonary ventilation030212 general & internal medicineMouthpieceTidal volumeSimulationMechanical ventilationVentilators Mechanicalbusiness.industryApnea alarmMechanical ventilatorEquipment DesignGeneral MedicineNeuromuscular diseaseEquipment Failure AnalysisEquipment Failure Analysi030228 respiratory systemTurn offClinical AlarmsAnesthesiaPulmonary ventilationBreathingMechanical ventilatorsClinical AlarmbusinessNoninvasive ventilationHumanRespiratory Care
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Assessment of a Modified Acoustic Lens for Electromagnetic Shock Wave Lithotripters in a Swine Model

2013

The acoustic lens of the Modularis electromagnetic shock wave lithotripter (Siemens, Malvern, Pennsylvania) was modified to produce a pressure waveform and focal zone more closely resembling that of the original HM3 device (Dornier Medtech, Wessling, Germany). We assessed the newly designed acoustic lens in vivo in an animal model.Stone fragmentation and tissue injury produced by the original and modified lenses of the Modularis lithotripter were evaluated in a swine model under equivalent acoustic pulse energy (about 45 mJ) at 1 Hz pulse repetition frequency. Stone fragmentation was determined by the weight percent of stone fragments less than 2 mm. To assess tissue injury, shock wave trea…

Pulse repetition frequencyShock wavemedicine.medical_specialtySwineUrologySus scrofaMicroscopy AcousticSensitivity and SpecificityArticlelaw.inventionFocal zoneKidney CalculiElectromagnetic FieldsPressure waveformlawLithotripsymedicineAnimalsPulse energyEquipment Safetybusiness.industryEquipment DesignAcoustic lensSurgeryLens (optics)Disease Models AnimalShock wave lithotripterFemalebusinessBiomedical engineering
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