Search results for "Eris"

showing 10 items of 3451 documents

Validation of the Sepsis MetaScore for Diagnosis of Neonatal Sepsis

2016

What’s known on this subject Neonates are at increased risk for developing sepsis, but this population often exhibits ambiguous clinical signs that complicate the diagnosis of infection. No biomarker has yet shown enough diagnostic accuracy to rule out sepsis at the time of clinical suspicion. What this study adds We show that a gene-expression-based signature is an accurate objective measure of the risk of sepsis in a neonate or preterm infant, and it substantially improves diagnostic accuracy over that of commonly used laboratory-based testing. Implementation might decrease inappropriate antibiotic use. Background Neonatal sepsis can have devastating consequences, but accurate diagnosis i…

0301 basic medicinemedicine.medical_specialtyPopulationSepsis03 medical and health sciences0302 clinical medicinePredictive Value of Tests030225 pediatricsDrug Resistance BacterialmedicineHumansIntensive care medicineeducationRetrospective Studieseducation.field_of_studyNeonatal sepsisReceiver operating characteristicClinical Laboratory Techniquesbusiness.industryRetrospective cohort studyOriginal ArticlesGeneral Medicinemedicine.diseaseAnti-Bacterial Agents030104 developmental biologyInfectious DiseasesROC CurvePredictive value of testsPediatrics Perinatology and Child HealthCohortBiomarker (medicine)Neonatal SepsisTranscriptomebusinessJournal of the Pediatric Infectious Diseases Society
researchProduct

Bayesian approach to urinary ESBL-producing Escherichia coli

2014

This is a retrospective study about the prevalence of ESBL-producing Escherichia coli (EEC) in urinary specimens from patients from the Comunitat Valenciana from January 2007 to December 2008. Data were retrieved from RedMIVA, and Bayesian generalized linear mixed models were considered to study the prevalence of EEC with regard to demographical and microbiological factors. The total number of infections considered was 164,502, the amount of urinary isolates was 70,827 belonging to 49,304 different patients, and 5,161 (7.3%) of the urinary isolates were EEC. Three out of four E. coli were isolated in women (76.8%), men showed higher rates of EEC (9.7% in men vs. 6.5% in women). EEC patients…

0301 basic medicinemedicine.medical_specialtyUrinary system030106 microbiologyPharmacologymedicine.disease_causePharmacovigilance03 medical and health sciencesAntibiotic resistanceInternal medicineControlMedicineRisk factorEscherichia colibusiness.industryMicrobiologia mèdicaRetrospective cohort studyAntimicrobialOmicsCiprofloxacinstomatognathic diseasesEstadística bayesianaBacteris patògensAntimicrobialbusinessmedicine.drug
researchProduct

Development and Validation of a New Clinical Prediction Model of Catheter-Related Thrombosis Based on Vascular Ultrasound Diagnosis in Cancer Patients

2020

Background: Central venous catheters are convenient for drug delivery and improved comfort for cancer patients, but they also cause serious complications. The most common complication is catheter-related thrombosis (CRT). Objectives: This study aimed to evaluate the incidence and risk factors for CRT in cancer patients and develop an effective prediction model for CRT in cancer patients. Methods: The development of our prediction model was based on a retrospective cohort (n = 3,131) from the National Cancer Center. Our prediction model was confirmed in a prospective cohort from the National Cancer Center (n = 685) and a retrospective cohort from the Hunan Cancer Hospital (n = 61). The predi…

0301 basic medicinemedicine.medical_specialtylcsh:Diseases of the circulatory (Cardiovascular) systemMultivariate analysis030204 cardiovascular system & hematologyCardiovascular Medicinecathetersnomogram03 medical and health sciences0302 clinical medicineInternal medicinemedicinecancerRisk factorProspective cohort studythrombosisOriginal ResearchReceiver operating characteristicbusiness.industryCancerRetrospective cohort studyNomogrammedicine.disease030104 developmental biologyrisk factorlcsh:RC666-701CohortCardiology and Cardiovascular MedicinebusinessFrontiers in Cardiovascular Medicine
researchProduct

Cognitive functioning throughout adulthood and illness stages in individuals with psychotic disorders and their unaffected siblings

2021

The European Community’s Seventh Framework Programme under grant agreement No. HEALTH-F2-2010-241909 (EUGEI); The Spanish sample was supported by the Spanish Ministry of Science and Innovation, Instituto de Salud Carlos III (SAM16PE07CP1, PI16/02012, PI19/024) (...)

0301 basic medicinevaliditymedicine.medical_treatmentCHILDHOODNeuropsychological TestsFAMÍLIAepisodeCognition0302 clinical medicineDEFICITSSettore MED/48 -Scienze Infermierist. e Tecn. Neuro-Psichiatriche e Riabilitat.MedicineCognitive impairmentPsychiatrySymptom severityCannabis useIMPAIRMENTABILITYPsychiatry and Mental healthSchizophreniaRELIABILITYNeuropsychological TestLife Sciences & BiomedicineHumanClinical psychologyAdultBiochemistry & Molecular Biologyimpairmentschizophrenia-patientsabilityGENETIC RISKPsychotic DisorderSCHIZOPHRENIA-PATIENTS03 medical and health sciencesCellular and Molecular NeuroscienceSDG 3 - Good Health and Well-beingSettore M-PSI/08 - Psicologia ClinicaHumansIn patientCognitive skillVALIDITYAntipsychoticMolecular BiologySettore MED/25 - PsichiatriaAgedCross-Sectional StudieDECLINEScience & Technologyreliabilitybusiness.industryWorking memorySiblingsNeurosciencesDiagnostic markersmedicine.diseaseCross-Sectional Studies030104 developmental biologydeficitsPsychotic DisordersSchizophreniaPSYCHOSIS COGNITION MULTICENTRIC STUDYNeurosciences & NeurologybusinessEPISODE030217 neurology & neurosurgeryMolecular Psychiatry
researchProduct

Functional test measures as risk indicators for low back pain among fixed-wing military pilots.

2015

Purpose The purpose of this study was to find out the risk value of functional fitness test (FFT) results for low back pain (LBP) among fixed-wing military pilots. Methods A total of 104 male military pilots were recruited for this study. The study was conducted with a self-administered questionnaire and FFT. The functional tests were performed in the beginning of study (baseline). The questionnaire was carried out at the baseline and 5 years later. Results The isometric low back endurance test result was associated with physical activity-related LBP experienced 5 years later. Demographic information was not associated with LBP. The prevalence of overall LBP was 71% and the flight-related L…

030110 physiology0301 basic medicineAdultMalemedicine.medical_specialtyFunctional trainingIsometric exerciseCohort Studies03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationFixed wingRisk Factorshealth services administrationSurveys and QuestionnairesPrevalenceMedicineHealth Status IndicatorsHumans030212 general & internal medicineMuscle StrengthRange of Motion Articularbusiness.industrypathological conditions signs and symptomsGeneral MedicineLow back painnervous system diseasesTest (assessment)body regionsOccupational DiseasesMilitary personnelPilotsMilitary PersonnelPhysical therapyExercise Testpopulation characteristicsAviation medicinemedicine.symptombusinessLow Back PainCohort studyJournal of the Royal Army Medical Corps
researchProduct

IMPACT OF CARTILAGE DAMAGE ON ARTHROGENIC MUSCLE INHIBITION IN PATIENTS WITH MENISCUS INJURIES

2016

Background: Knee traumata are associated with arthrogenic muscle inhibition (AMI). We aimed to identify impact factors on AMI. Methods: A total of 37 patients with meniscus injuries were interviewed and examined for maximum isometric knee extensor force preoperatively. We analyzed AMI as relative maximum isometric force between healthy and injured legs. Regression analyses were computed to evaluate associations between an AMI with muscle-strength reduction [Formula: see text]% and several parameters and between cartilage damage[Formula: see text][Formula: see text][Formula: see text]stadium 3 and several parameters. ROC curves were calculated to investigate effectiveness of age and pain at…

030203 arthritis & rheumatologymedicine.medical_specialtyReceiver operating characteristicbusiness.industryCartilageMuscle weakness030229 sport sciencesIsometric exerciseMeniscus (anatomy)Logistic regressionMuscle atrophySurgery03 medical and health sciences0302 clinical medicinemedicine.anatomical_structureInternal medicineConcomitantCardiologyMedicineOrthopedics and Sports Medicinemedicine.symptombusinessJournal of Musculoskeletal Research
researchProduct

Topographical geometric factors governing the biological activities of methomyl derivatives on binding receptors of maize mitochondria

1986

Abstract The topographical study of the binding receptors of T and N mitochondria was undertaken with methomyl derivatives acting as molecular probes. The two biological activities related to topography and geometric isomerism are distinguishable from the receptor sites of T and N mitochondria.

0303 health sciences010405 organic chemistry[SDV]Life Sciences [q-bio]030302 biochemistry & molecular biologyOrganic ChemistryMethomylMitochondrion01 natural sciencesBiochemistry0104 chemical sciences[SDV] Life Sciences [q-bio]03 medical and health scienceschemistry.chemical_compoundchemistryBiochemistryDrug DiscoveryReceptorMolecular probeMolecular BiologyCis–trans isomerismComputingMilieux_MISCELLANEOUS
researchProduct

Biogeographical patterns of soil molecular microbial biomass as influenced by soil characteristics and management

2011

Aim The spatial organization of soil microbial communities on large scales and the identification of environmental factors structuring their distribution have been little investigated. The overall objective of this study was to determine the spatial patterning of microbial biomass in soils over a wide extent and to rank the environmental filters most influencing this distribution.

0303 health sciencesGlobal and Planetary ChangeBiomass (ecology)EcologyLand useEcologyBiogeography04 agricultural and veterinary sciences15. Life on landSpatial distributioncomplex mixturesSoil characteristicsSoil management03 medical and health sciencesSoil water040103 agronomy & agriculture0401 agriculture forestry and fisheriesEnvironmental scienceEcology Evolution Behavior and SystematicsSpatial organization030304 developmental biologyGlobal Ecology and Biogeography
researchProduct

Geometry of conjugated double bonds of CLA isomers in a commercial mixture and in their hepatic 20∶4 metabolites

1999

Rats were fed a fat-free diet for 2 wk. After this period, while maintaining the animals on the same diet, the rats were given intragastrically 180 mg per day of a mixture of conjugated linoleic acids (CLA) as triacylglycerols. Gas chromatography mass spectrometry (GC-MS) analyses of this mixture, as well as hydrazine reduction and GC-MS and GC-Fourier transform infrared analyses of the resulting monoenes, revealed the presence of two major isomers, the 9c,11t- and the 10t,12c-18:2 accompanied by smaller amounts of the 8t, 10c and the 11c, 13t-18:2 isomers. Minor quantities of cis,cis and trans,trans conjugated isomers also were detected. The total fatty acid methyl esters from the liver li…

030309 nutrition & dieteticsLinoleic acidHydrazineFraction (chemistry)Conjugated systemMass spectrometryBiochemistryGas Chromatography-Mass Spectrometry03 medical and health scienceschemistry.chemical_compoundIsomerismSpectroscopy Fourier Transform InfraredAnimals[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry Molecular Biology/Biochemistry [q-bio.BM][SDV.BBM.BC] Life Sciences [q-bio]/Biochemistry Molecular Biology/Biochemistry [q-bio.BM]Chromatography High Pressure LiquidTriglyceridesComputingMilieux_MISCELLANEOUS030304 developmental biologychemistry.chemical_classification0303 health sciencesChromatographyChemistryFatty AcidsOrganic ChemistryFatty acidCell BiologyDietRatsSilver nitrateHydrazinesLinoleic AcidsLiverRATChromatography Thin LayerLipids
researchProduct

Pain Education in Schools of Nursing: a Survey of the Italian Academic Situation.

2018

Introduction: Proper assessment of pain is imperative for the development of an effective pain management plan and is a core responsibility of nurses and healthcare professionals. This article describes the contents of Italian on-line bachelor's in nursing degree programs, with particular focus on pain management.Method: A descriptive study was made on curricula published and available on-line in Italian Nursing Schools, and the concordance with the standards set by the Consensus Curriculum on Pain for Nursing ofthe International Association for the Study of Pain (IASP, 2015) was analyzed.Results: Of all the bachelor programs published on-line, 42.6% offered programs and courses specificall…

030504 nursingSchools NursingBachelor in NursingEducation Nursing BaccalaureateGeneral MedicineSettore MED/45 - Scienze Infermieristiche Generali Cliniche E Pediatriche03 medical and health sciences0302 clinical medicineItalySurveys and QuestionnairesHumansPain ManagementpainCore-curriculumCurriculum0305 other medical sciencePsychologyHumanities030217 neurology & neurosurgeryProfessioni infermieristiche
researchProduct