Search results for "Eris"

Force Distribution Analysis of Mechanochemically Reactive Dimethylcyclobutene

2013

Internal molecular forces can guide chemical reactions, yet are not straightforwardly accessible within a quantum mechanical description of the reacting molecules. Here, we present a force-matching force distribution analysis (FM-FDA) to analyze internal forces in molecules. We simulated the ring opening of trans-3,4-dimethylcyclobutene (tDCB) with on-the-fly semiempirical molecular dynamics. The self-consistent density functional tight binding (SCC-DFTB) method accurately described the force-dependent ring-opening kinetics of tDCB, showing quantitative agreement with both experimental and computational data at higher levels. Mechanical force was applied in two different ways, namely, exter…

FUNCTIONAL STUDY ON THE ROLE OF TACHYKININS IN COLONIC PERISTALTIC ACTIVITY IN MICE

2009

Because the role of tachykinin receptors in colonic peristalsis remains incompletely understood, we studied the effect of tachykinin receptor antagonists on mouse colonic peristaltic activity. Peristaltic activity was assessed by quantifying the amplitude and interval of distension-induced pressure waves in proximal and distal colon segments of mice using a modified Trendelenburg set-up. We studied the effect of the NK1, NK2 and NK3 tachykinin receptor antagonists RP67580 (2 mM), nepadutant (1 mM) and SR142801 (0.3 mM) respectively. Gradual distension of proximal and distal colon segments induced repetitive rhythmic pressure waves which were blocked by tetrodotoxin (1 mM) and virtually abol…

Optimismin ja tavoiteristiriitojen yhteydet työhyvinvointiin nuorilla esimiehillä

2014

Tässä tutkimuksessa selvitettiin optimismin ja tavoiteristiriitojen yhteyksiä työn imuun ja työuupumukseen nuorilla esimiehillä. Tutkimuksen lähtöoletuksena oli, että optimistit kokevat tavoiteristiriitojen kielteiset vaikutukset hyvinvointiin muita vähäisempinä. Tämän lisäksi korkean optimismin oletettiin olevan yhteydessä vähäisempiin tavoiteristiriitoihin. Tutkimuksessa selvettiin myös tavoiteristiriitojen vaikutuksia työhyvinvointiin. Tutkimuksessa muuttujien vaikutuksia työhyvinvointiin selvitettiin poikkileikkaus- ja pitkittäistutkimusasetelmassa. Tutkimus perustuu vuonna 2006 aloitettuun nuorten esimiesten henkilökohtaisia tavoitteita ja työhyvinvointia kartoittavaan pitkittäisaineis…

Associations Between Reading Skills, Interest in Reading, and Teaching Practices in First Grade

2017

ABSTRACTThis study examined associations between classroom-level reading fluency, comprehension, interest in reading, and teaching practices. Participants were 466 children from 21 classrooms. Reading fluency and interest were assessed at the beginning and end of Grade 1, reading comprehension at the end of Grade 1. Teaching practices were observed with the Early Childhood Classroom Observation Measure (ECCOM). Teachers were more likely to use teacher-directed methods in classrooms where children had poorer initial reading fluency. In classrooms with mostly child-centered methods, children showed better reading fluency, comprehension, and higher interest, whereas in classrooms with predomin…

"Se, että lapsia huijataan, että kiivetään puuhun, vaikka siellä on takana tikapuut ..." : esiopetusikäisen teatterissakäyntikokemus

2008

Creating the Consumer girl : A Study of Consumerism in Seventeen Magazine

2010

 Kriittisen diskurssianalyysin perusajatuksen mukaan kieli ei vain heijasta todellisuutta vaan myös rakentaa sitä. Kielenkäytöllä voidaan siis katsoa olevan valtaa ihmisten uskomusten, arvojen ja tietämyksen määrittelyssä. Samanlaista valtaa on myös medialla, jota feministinen mediatutkimus tutkii stereotyyppisiä ja normalisoivia sukupuolikäsityksiä rakentavana sukupuoliteknologiana . Usein median vallankäyttö tapahtuu juuri kielenkäytön kautta. Kun tietyt puhetavat eli diskurssit toistuvat mediassa tarpeeksi usein, muokkaavat ne myös yleisiä mielipiteitä. Hyvä esimerkki sukupuoliteknologiana toimivasta mediasta ovat naistenlehdet, jotka rakentavat rajattua ja usein kulutuskeskeistä kuvaa n…

Transferencia génica hepática hidrodinámica en modelos de cerdo in vivo y segmento humano ex vivo

2015

Introducción: La terapia génica es una estrategia terapéutica que pretende utilizar ácidos nucleicos como medicamentos para el tratamiento temporal o permanente de patologías hereditarias o adquiridas. En base al vehículo utilizado para entregar el gen, podemos clasificar la terapia génica en dos grupos: la terapia génica viral (vectores virales) y la terapia génica no viral (vectores no virales o ADN desnudo). La terapia no viral resulta menos eficiente pero más segura. La hidrofección (transferencia génica hidrodinámica) ha mostrado un gran potencial, con resultados terapéuticos en ratón. Sin embargo, cuando la hidrofección se ha trasladado a animales de mayor tamaño, el procedimiento ha …

Can foliar-applied nutrients improve caraway (Carum carvi L.) seed oil composition?

2021

Caraway seeds contain between 0.5–7% essential oil, rich in monoterpenes that have a characteristic aroma and chemical properties. Caraway oil has several bioactive compounds that are of industrial importance, particularly for pharmaceutical and health care products. Carvone and limonene are the main terpenes present in caraway oil, which along with some unique fatty acids (i.e. petroselinic acid) determine caraway (Carum carvi L.) oil quality. Both terpenes are important raw materials for industrial applications and their concentration influences the price of caraway seed and oil, hence there is need for identifying management practices that may increase the concentration of these and othe…

Terre di Confine

2011

Narrativa: Il libro presenta il viaggio iniziatico del protagonista attraverso le Terre di Confine tra la realtà e la fantasia, tra lucidità e pazzia, tra il mondo materiale ed il mondo spirituale. Un fantasy eroico che affronta temi di critica sociale, intrecciati a concetti di esoterismo occidentale ed orientale. Il protagonista, sul quale grava un profondo senso di mancanza, vive una condizione di intenso disagio psicologico. Il viaggio attraverso i mondi rivelerà il perchè di questo senso di inadeguatezza e gli fornirà le conoscenze necessarie per svolgere la missione a cui è destinato. Per ottenere la comprensione di ciò che l’attende dovrà riscoprire tutto ciò che dava per scontato, v…

Longitudinal and cross-sectional associations of adherence to 24-hour movement guidelines with cardiometabolic risk

2022

This study aimed to examine 1) adherence to 24-hour movement guidelines over a 2-year follow-up in children aged 6-8 years and 2) association of this adherence with cardiometabolic risk factors. Physical activity and sleep were assessed by a monitor combining heart rate and accelerometry measurements. Screen time was reported by the parents. Body fat percentage, waist circumference, blood glucose, serum insulin, plasma lipids and blood pressure were assessed, and a cardiometabolic risk score was calculated using z-scores. Children were classified as meeting the guidelines if they had on average ≥60min/day of moderate-to-vigorous physical activity during the valid days; ≤120min/day of screen…