Search results for "Erk"
showing 10 items of 2599 documents
Christianity and digital culture : analysis of users' experiences of the christian social networking site in Taiwan - Walei
2011
Social Networking Sites (SNSs) have been a popular phenomenon worldwide, while religion in Computer Mediated Communication (CMC) studies has gained more academic attention. Walei as a pioneering social networking site is founded by a group of Protestant Christians targeting at the youth in Taiwan, and it exemplifies religious application on the Internet. This thesis investigates what role such a website plays both for its users and against its competition, particularly in the non-Christian cultural context. Using online interviews with nine users of Walei, how the interactivity affects Christian users‟ religious identity and the impression of non-Christian users toward Christianity is explo…
Female style vs. male style or something in between? : a case study on gendered communication on the Humans of New York Facebook page
2015
Sosiaalinen media on viime vuosikymmenen aikana mullistanut internetin avulla tapahtuvaa viestintää ja sen tuomia uusia mullistuksia onkin tutkittu tieteellisesti paljon viime aikoina. Sukupuolen ja kielen roolia sosiaalisen median myllerryksessä ei viestinnällisestä näkökulmasta kuitenkaan ole tutkittu kovin paljon ja siksi tämän tutkimuksen tarkoituksena oli kartoittaa, millaista naisten ja miesten kielenkäyttö on nykyään internetissä ja miten se peilautuu aiempien tutkimustulosten valossa. Tutkimuksen aineisto koostui 170 tavallisten ihmisten kirjoittamista kommenteista, jotka valittiin suositulta Humans of New York Facebook-sivulta tammikuun 2015 aikana. Nämä kommentit jaettiin laadulli…
Telia Crowd Insights -tietojen hyödyntäminen pandemiatietoisuuden parantamiseksi Keski-Suomessa
2021
Telia Crowd Insights -tietojen hyödyntäminen pandemiatietoisuuden parantamiseksi KeskiSuomessa on Keski-Suomen liiton rahoittama hanke, jolla pyritään selvittämään, että pystytäänkö ihmisten ja ihmisvirtojen liikkeitä seuraamalla saavuttamaan parempi tilannekuva pandemia tilanteessa. Hankkeen tarkoituksena on keskittyä erilaisiin liikenteenseurantaratkaisuihin sekä tutkia koronaviruksen aiheuttamia vaikutuksia maakunnassa tapahtuvaan liikenteeseen ja liikkumiseen. Keväällä 2020 tuli voimaan poikkeukselliset olosuhteet, joiden takia liikenne muuttui merkittävästi erilaisten rajoitusten ja yleisen varovaisuuden vuoksi. Tämä on yksi merkittävimmistä ilmiöistä, joita projektissa pyritään tutkim…
Safety and efficacy outcomes after intranasal administration of neural stem cells in cerebral palsy : a randomized phase 1/2 controlled trial
2023
Abstract Background Neural stem cells (NSCs) are believed to have the most therapeutic potential for neurological disorders because they can differentiate into various neurons and glial cells. This research evaluated the safety and efficacy of intranasal administration of NSCs in children with cerebral palsy (CP). The functional brain network (FBN) analysis based on electroencephalogram (EEG) and voxel-based morphometry (VBM) analysis based on T1-weighted images were performed to evaluate functional and structural changes in the brain. Methods A total of 25 CP patients aged 3–12 years were randomly assigned to the treatment group (n = 15), which received an intranasal infusion of NSCs loade…
eCRM:n ja verkkokaupan rooli asiakastyytyväisyyden luomisessa
2010
Heikkinen, Hanna Karoliina Tietojärjestelmätieteen kandidaatintutkielma /Hanna Karoliina Heikkinen Jyväskylä: Jyväskylän yliopisto, 2009, 38 s. Kandidaatintutkielma Yrityksien liiketoiminta- ja ajattelumallit ovat siirtyneet tuotantokeskeisestä asiakaskeskeiseen. Tässä tutkielmassa tarkastellaan asiakaskeskeistä liiketoimintaa eri näkökulmista. Asiakaskeskeiseen liiketoimintaan kuuluu olennaisena osana CRM-käsite (Customer Relationship Management), jolle on kirjallisuudessa esitetty useita erilaisia määritelmiä. Tässä tutkielmassa CRM:ää käsitellään yrityksen kokonaisvaltaisena strategiana harjoittaa liiketoimintaa. CRM-liiketoimintastrategiaan sisältyy olennaisena osana myös teknologiset …
Identification of Merkel cells in human skin by specific cytokeratin antibodies:
1984
Merkel cells are special neurosecretory cells which, in adult human skin, are usually very scarce. By immunofluorescence microscopy using antibodies to human cytokeratin polypeptide no. 18, we localized distinct non-keratinocyte cells in the glandular ridges of human fetal and adult plantar epidermis. Using electron and immunofluorescence microscopy, these cells were identified as Merkel cells containing typical neurosecretory granules as well as bundles of intermediate-sized filaments and desmosomes. Two-dimensional gel electrophoresis of the cytoskeletal fractions of microdissected epidermal preparations highly enriched in Merkel cells indicated the presence of cytokeratin polypeptides no…
Body mass index and baseline platelet count as predictive factors in Merkel cell carcinoma patients treated with avelumab
2023
BackgroundMerkel cell carcinoma (MCC) is a rare and aggressive skin cancer, associated with a worse prognosis. The Immune Checkpoint Inhibitors (ICIs) avelumab and pembrolizumab have been recently approved as first-line treatment in metastatic MCC (mMCC). The clinical observation of improved outcomes in obese patients following treatment with ICIs, known as the “obesity paradox”, has been studied across many types of tumors. Probably due to the rarity of this tumor, data on mMMC patients are lacking.Patients and methodsThis is an observational, hospital-based, study to investigate the role of Body Mass Index (BMI) as predictive biomarker of ICI response in mMCC patients treated with aveluma…
Tracing the fate of microplastic carbon in the aquatic food web by compound-specific isotope analysis
2019
Increasing abundance of microplastics (MP) in marine and freshwaters is currently one of the greatest environmental concerns. Since plastics are fairly resistant to chemical decomposition, breakdown and reutilization of MP carbon complexes requires microbial activity. Currently, only a few microbial isolates have been shown to degrade MPs, and direct measurements of the fate of the MP carbon are still lacking. We used compound-specific isotope analysis to track the fate of fully labelled 13C-polyethylene (PE) MP carbon across the aquatic microbial-animal interface. Isotopic values of respired CO2 and membrane lipids showed that MP carbon was partly mineralized and partly used for cell growt…
Monthly Bonaire coral Sr/Ca and oxygen isotope data from 118 kyr ago (coral BON-5-D)
2015
The end of the last interglacial period, ~118 kyr ago, was characterized by substantial ocean circulation and climate perturbations resulting from instabilities of polar ice sheets. These perturbations are crucial for a better understanding of future climate change. The seasonal temperature changes of the tropical ocean, however, which play an important role in seasonal climate extremes such as hurricanes, floods and droughts at the present day, are not well known for this period that led into the last glacial. Here we present a monthly resolved snapshot of reconstructed sea surface temperature in the tropical North Atlantic Ocean for 117.7±0.8 kyr ago, using coral Sr/Ca and d18O records. W…
Looking for Feminist Pragmatist Roots of Degrowth Ideas: Jane Addams, Charlotte Perkins Gilman, Caroline Bartlett Crane
2022
The aim of the paper is a search of feminist pragmatist roots of degrowth ideas. The starting point is the question of whether in views of the members of the Progressive Movement the idea of progress has always implied the economic (and industrial) growth. Searching for counter-examples leads me to ideas of ecofeminism and feminist critics of capitalism in the previous turn of the centuries. The ideas of ecofeminism were developed by women associated with the Department of Sociology at the University of Chicago and the social settlement Hull House. They observed a link between the exploitation of subordinate members of a society and the degradation of nature in Western cultural values. The …