Search results for "Erk"

showing 10 items of 2599 documents

Nuorten identiteetti-ilmaisu IRC-Galleriassa : ilmaisukeinoina nimimerkit, profiilikuvat ja kuvatekstit

2010

NUORTEN IDENTITEETTI-ILMAISU IRC-GALLERIASSA Ilmaisukeinoina nimimerkit, profiilikuvat ja kuvatekstit Piia Pyykkönen Sosiologia Pro gradu-tutkielma Yhteiskuntatieteiden ja filosofian laitos Jyväskylän yliopisto Ohjaaja: Terhi-Anna Wilska Syksy 2010 Sivumäärä: 113 Pro gradu-tutkielmani käsittelee nuorten identiteetti-ilmaisua IRC-Galleriassa. Identiteettiilmaisun selvittämisessä ovat apuna nuorten profiilikuvat, niihin liittyvät tekstit sekä nuorten itselleen keksimät nimimerkit. Aineisto on kerätty internetin sosiaalisesta yhteisöpalvelusta IRC-Galleriasta. Aineisto koostuu neljässä eri yhteisössä olevien jäsenten profiilikuvista, niihin liittyvistä kuvateksteistä ja jäsenten nimimerkeistä.…

IRC-Gallerianimimerkitnuoretverkkoyhteisötosakulttuuritidentiteettivisuaalinen kulttuurikuvat
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Coping with pandemics using social network sites: A psychological detachment perspective to COVID-19 stressors

2022

Prior research has often portrayed information technology (IT) as a stressor. In this paper, we propose and demonstrate that IT can also be an effective means of coping with life stressors, including those induced by pandemics such as COVID-19. We thus deviate from the common IT-as-a-stressor perspective and adopt an IT-as-a-coping-mechanism viewpoint. To this end, we apply the stressor-detachment model from organisational psychology to the use of social network sites (SNSs) in coping with stressors wrought by the COVID-19 pandemic. We examine psychological well-being as our dependant variable and introduce psychological detachment through SNS use as a mediator and moderator of the associat…

ITsosiale nettverkVDP::Social science: 200::Economics: 210Management of Technology and Innovation:Samfunnsvitenskap: 200::Økonomi: 210::Bedriftsøkonomi: 213 [VDP]sosiale medierCOVID-19Business and International ManagementstresshåndteringApplied Psychologypandemi
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Analysis of cIAP1 oncogenic properties : importance of cIAP1-TRAF2 interplay

2021

Analysis of cIAP1 oncogenic properties: cIAP1 and TRAF2 ubiquitin ligases duo in tumor growth.cIAP1 (cellular Inhibitor of APoptosis-1) is a signaling intermediate belonging to the IAP (Inhibitor of APoptosis) family. This E3 ubiquitin ligase protein shows oncogenic properties. cIAP1 expression is frequently altered in various human tumor samples and represents a marker of bad prognosis and resistance to chemotherapies. Some IAP antagonists have been synthesized. They showed promising results in preclinical study and some of them are now being tested in clinical study. Unfortunately, these molecules are poorly specific as they can neutralize several IAP family members. Moreover, the mechani…

Il-6ErkTraf2[SDV.BBM] Life Sciences [q-bio]/Biochemistry Molecular BiologyNf-KbCiap1Cancer
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Somehuomion jäljillä : käyttäjien reagointi journalistisiin sisältöihin Ilta-Sanomien ja Helsingin Sanomien Facebook-sivuilla

2016

Tämän tutkimuksen tarkoituksena oli selvittää yhteisöpalvelu Facebookin käyttäjien reagointia suomenkielisiin journalistisiin sisältöihin. Toisaalta tarkoituksena oli löytää sisällöistä ominaisuuksia, jotka ovat yhteydessä niiden saamaan huomioon sosiaalisessa mediassa. Tutkimusaihe on tärkeä, sillä ihmiset päätyvät yhä useammin journalististen sisältöjen äärelle sosiaalisen median palveluiden kautta. Tutkimus toteutettiin analysoimalla Ilta-Sanomien ja Helsingin Sanomien Facebook-sivuilta kerättyä data-aineistoa. Aineistossa oli kaikki medioiden julkaisemat Facebook-päivitykset syyskuulta 2015. Aineiston avulla oli mahdollista tarkastella muun muassa päivitysten keräämiä tykkäyksiä, kommen…

Ilta-Sanomat (sanomalehti)verkkojournalismiFacebookHelsingin Sanomat (sanomalehti)journalismisosiaalinen media
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Generating Hyperspectral Skin Cancer Imagery using Generative Adversarial Neural Network

2020

In this study we develop a proof of concept of using generative adversarial neural networks in hyperspectral skin cancer imagery production. Generative adversarial neural network is a neural network, where two neural networks compete. The generator tries to produce data that is similar to the measured data, and the discriminator tries to correctly classify the data as fake or real. This is a reinforcement learning model, where both models get reinforcement based on their performance. In the training of the discriminator we use data measured from skin cancer patients. The aim for the study is to develop a generator for augmenting hyperspectral skin cancer imagery. peerReviewed

Imagery PsychotherapySkin NeoplasmsComputer science0211 other engineering and technologiesComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION02 engineering and technologygenerative adversarial neural networksneuroverkotMachine learningcomputer.software_genre030218 nuclear medicine & medical imagingMachine Learningihosyöpä03 medical and health sciencesAdversarial system0302 clinical medicineHumansLearningReinforcement learning021101 geological & geomatics engineeringArtificial neural networkskin cancerbusiness.industryspektrikuvausHyperspectral imagingComputingMethodologies_PATTERNRECOGNITIONkuvantaminenNeural Networks ComputerArtificial intelligencebusinesscomputerGenerative grammarGenerator (mathematics)
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Modeling wave propagation in elastic solids via high-order accurate implicit-mesh discontinuous Galerkin methods

2022

A high-order accurate implicit-mesh discontinuous Galerkin framework for wave propagation in single-phase and bi-phase solids is presented. The framework belongs to the embedded-boundary techniques and its novelty regards the spatial discretization, which enables boundary and interface conditions to be enforced with high-order accuracy on curved embedded geometries. High-order accuracy is achieved via high-order quadrature rules for implicitly-defined domains and boundaries, whilst a cell-merging strategy addresses the presence of small cut cells. The framework is used to discretize the governing equations of elastodynamics, written using a first-order hyperbolic momentum-strain formulation…

Implicitly-defined meshesMechanical EngineeringApplied MathematicsMathematicsofComputing_NUMERICALANALYSISComputational MechanicsDiscontinuous Galerkin methodsGeneral Physics and AstronomyImplicitly-defined mesheNumerical Analysis (math.NA)Mathematical SciencesComputer Science ApplicationsHigh-order accuracyEngineeringMechanics of MaterialsEmbedded-boundary methodDiscontinuous Galerkin methodFOS: MathematicsElastodynamicsEmbedded-boundary methodsMathematics - Numerical Analysis
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Pedagogical experiments with MathCheck in university teaching

2019

MathCheck is a relatively new online tool that gives students feedback on their solutions to elementary university mathematics and theoretical computer science exercises. MathCheck was designed with constructivism learning theory in mind and it differs from other online tools as it checks the solutions step by step and shows a counter-example if the step is incorrect. It has been in student use since the autumn of 2015 and under design-based research from the first online day. The main research questions of this study are the following. 1) How can the usage of MathCheck support the aspects of conceptual understanding and procedural fluency of constructivism learning? 2) How can MathCheck em…

Independent studyeducationPoint (typography)matematiikkapedagogymathematicsEducational technologyComputer-Assisted InstructionWorkloadverkko-oppiminenlcsh:Education (General)FluencypedagogiikkaMathCheckkoulutusConstructivism (philosophy of education)Mathematics educationComputingMilieux_COMPUTERSANDEDUCATIONUniversity teachingverkko-opetuslcsh:L7-991lcsh:Science (General)lcsh:Q1-390LUMAT
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Teollisen internetin määrittely kirjallisuudessa

2016

Teollisen internetin (engl. Industrial Internet) käsite ei ole täysin vakiintunut kirjallisuudessa. Sillä on useita erilaisia englanninkielisiä vastineita, joiden määrittelyt poikkeavat jonkin verran toisistaan. Teollisella internetillä tarkoitetaan usein teknologisia ratkaisuja, joilla pyritään luomaan teollisia sovelluksia prosessien optimointiin, tehostamiseen, mittaamiseen ja tarkkailuun. Laiteverkolla (engl. Internet of Things) taas tarkoitetaan teknologiaa, joka mahdollistaa internetin laajentumiseen tavanomaisilta alustoilta omaan ympäristöömme: vaatteisiin, huonekaluihin ja kulkuneuvoihin. Kirjallisuuskatsauksessa tutkittiin teollisen internetin määrittelyä kirjallisuudessa. Katsauk…

Industrial Internetdefinition of the conceptInternet of Thingsteollinen internetlaiteverkkokäsitteen määrittely
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Comparing Alternative Algorithms to Analyze the Beerkan Infiltration Experiment

2014

The increasing interest in the Beerkan Estimation of Soil Transfer parameters (BEST) procedure of soil hydraulic characterization justifies an assessment of alternative methods to analyze infiltration data. The BEST-slope and BEST-intercept algorithms allow estimation of soil sorptivity, S, and saturated soil hydraulic conductivity, Ks, using the transient part of the experimental infiltration curve and the slope and the intercept, respectively, of the linear portion of this curve. With reference to 401 runs performed in Sicily (Italy) and Burundi, this investigation showed that these two algorithms differed by the number of successful runs (positive S and Ks values), with BEST-intercept yi…

Infiltration (hydrology)Soil ScienceSoil scienceBEST Beerkan Estimation of Soil Transfer parameter3D three dimensionalGeologySoil Science Society of America Journal
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INVESTIGATIONS ON INFILTRATION METHODS FOR AN IMPROVED SOIL HYDRAULIC CHARACTERIZATION

2020

Infiltration soil hydraulic properties saturated soil hydraulic conductivity surface hydrological processes BEST procedure for soil hydraulic characterization two-stage methodology height of water pouring effects soil sealing rainfall simulation beerkan infiltration experiment BEST algorithms laboratory investigation falling-head one dimensional infiltration simplified falling-head technique automatic infiltrometer Arduino parameterization of model for single-ring infiltration monitoring saturated hydraulic conductivity
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