Search results for "Erk"

showing 10 items of 2599 documents

Rethinking webcomics : webcomics as a screen based medium

2013

So far, webcomics, or online comics, have been discussed mostly in terms of ideologies of the Internet such as participatory culture or Open Source. Not much thought, however, has been given to webcomics as a new way of making comics that need to be studied in their own right. In this thesis a diverse set of webcomics such as Questionable Content, A Softer World and FreakAngels is analyzed using a combination of N. Katherine Hayles’ Media Specific Analysis (MSA) and the neo-semiotics of comics by Thierry Groensteen. By contrasting print- and web editions of webcomics, as well as looking at web-only webcomics and their methods for structuring and creating stories, this thesis shows that webc…

Internetverkkosarjakuvattutkimussarjakuvat
researchProduct

Finnish fandom of Japanese popular culture : what are the Finns doing for anime, manga, and J-rock?

2010

InternetverkkoyhteisötJapaniverkostoituminenmangatrockfaniuskulttuurianimetdigitaalinen kulttuuriSuominuorisokulttuuripopulaarikulttuuriJ-rock
researchProduct

Experiences, reputation, references and decision-making in an online hospitality network

2014

The aim of this thesis was to analyse behavioural patterns that occur after a negative experience during a hospitality exchange. The focus of this study is the largest online hospitality network to date, the CouchSurfing Project. CouchSurfing enables travellers to connect and to offer each other help in form of a free hospitality exchange. Furthermore, CouchSurfing presents a platform for cultural exchange and the possibility for members to connect in this online-offline community. As part of a qualitative study, a voluntary online questionnaire has been distributed and answered by 35 CouchSurfing members. The results give insight of how they deal with a negative experience after offline in…

InternetverkkoyhteisötkokemuksetmainesuosituksetCouchSurfingvaihtokauppasohvasurffausvieraanvaraisuusKvalitatiivinen tutkimusverkkopalvelut
researchProduct

Digitaalinen leirinuotio ja laiskan tekstipaja näkökulmia koti- ja ulkomaisiin avoimiin kirjoittajasivustoihin

2008

Internetverkkoyhteisötpalautekirjoittajapiiritkirjoittaminen
researchProduct

Netti-televisio Vision synty ja käyttökokemukset

2003

Internetverkotkäytettävyystelevisiokokemuksetvideokäyttö
researchProduct

Sukupuolistunut väkivalta Vares- ja Wallander-elokuvissa

2017

Sukupuolistunut väkivalta Vares- ja Wallander-elokuvissaArtikkelissa tarkastellaan sukupuolistuneen väkivallan representaatioita ruotsalaisissa Wallander-elokuvissa (2005–2006) ja suomalaisissa Vares-elokuvissa (2004–2015). Huomion kohteena on, miten sukupuoli ja seksuaalisuus näyttäytyvät näiden pohjoismaisten rikoselokuvien kerronnassa osana väkivaltaan liitettyjä merkityksiä, selityksiä ja asenteita. Väkivallan kulttuurisia merkityksiä analysoidaan feministisen media- ja kulttuurintutkimuksen sekä feministisen väkivaltatutkimuksen näkökulmasta. Analyysi kohdistuu siihen, mitä ja millaista väkivaltaa Vareksissa ja Wallandereissa esitetään, mitä selityksiä väkivallalle tarjoutuu sekä milla…

Interpretation (philosophy)väkivaltamerkityksetkerrontaasenteetmerkitykset (semantiikka)Gender studiesHuman sexualityVertaisarvioidut artikkelitFeminist researchseksuaalisuuselokuvatsukupuolisukupuolittuminenelokuvaCultural studiesNarrativeSociologyLähikuva – audiovisuaalisen kulttuurin tieteellinen julkaisu
researchProduct

Towards Successful Implementation of a Virtual Classroom for Vocational Higher Education in Indonesia

2019

The virtual classroom continues to grow, but it is becoming more and more the norm, and it is fundamentally different from the vocational students at the Indonesian university. With the promised benefits of the virtual classroom, many challenges and difficulties come in the implementation. Although there are already successful design principles for virtual classrooms that support organizations in overcoming the challenges, the approach to implementing the design principles of virtual classroom at the vocational higher education in Indonesia is still lacking. In this study, we aim to answer the research gap and used the design sciences research by interviewing the lecturers to design the sol…

InterviewHigher educationkehittämistutkimusDesign elements and principlesIndonesian higher education02 engineering and technology03 medical and health sciences0302 clinical medicine0202 electrical engineering electronic engineering information engineeringMathematics educationComputingMilieux_COMPUTERSANDEDUCATIONSociologyverkko-opetusdesign challengesVirtual classroomdesign principlesammatillinen koulutusbusiness.industryOnline learning030229 sport sciencesverkko-oppiminenlanguage.human_languageammattikoulutusIndonesianIndonesiaVocational educationlanguage020201 artificial intelligence & image processingbusiness
researchProduct

mGluR2/3 agonist LY379268, by enhancing the production of GDNF, induces a time-related phosphorylation of RET receptor and intracellular signaling Er…

2011

In the present study we aimed to verify if the enhancement of glial cell line-derived neurotrophic factor (GDNF) production in mouse striatum following treatment with LY379268 may also induce in the nigrostriatal system a time-related activation of RET receptor and its specific intracellular signaling. For this purpose, we have investigated the effects of LY379268 treatment on RET phosphorylation at the Tyr1062 and on downstream signaling Erk1/2, Akt and PLCγ1 pathway activation. The results showed that treatment with LY379268 (3 mg/kg) induces a significant increase of GDNF levels and time-related RET and Erk1/2 phosphorylation in the striatum. These increases were detected at 24 h and 48 …

Intracellular FluidMalemedicine.medical_specialtyTime FactorsMAP Kinase Signaling SystemSubstantia nigraStriatumReceptors Metabotropic GlutamateSettore BIO/09 - FisiologiaCellular and Molecular NeuroscienceMiceErk1/2Neurotrophic factorsInternal medicinemedicineGlial cell line-derived neurotrophic factorAnimalsGlial Cell Line-Derived Neurotrophic FactorAmino AcidsPhosphorylationReceptormGluR2/3Protein kinase BPharmacologyMitogen-Activated Protein Kinase 3biologyChemistryProto-Oncogene Proteins c-retLY379268Bridged Bicyclo Compounds HeterocyclicGDNFCorpus StriatumUp-RegulationMice Inbred C57BLEndocrinologynervous systembiology.proteinPhosphorylationTrK phosphorylationRETGDNF family of ligandsNeuropharmacology
researchProduct

2015

Aims To investigate the feasibility and to compare three devices measuring intraocular pressure (IOP) in mucopolysaccharidosis patients (MPS): iCare rebound tonometer (RT), Perkins applanation tonometer (PAT) and ocular response analyzer (ORA)

Intraocular pressuremedicine.medical_specialtyMultidisciplinarygenetic structuresbusiness.industryMucopolysaccharidosisGlaucomaREBOUND TONOMETRYmedicine.diseaseeye diseasesPerkins applanation tonometryPerkins applanation tonometerOphthalmologyMedicinesense organsbusinessPLOS ONE
researchProduct

HALE-IoT: HArdening LEgacy Internet-of-Things devices by retrofitting defensive firmware modifications and implants

2022

Internet-Of-Things (IoT) devices and their firmware are notorious for their lifelong vulnerabilities. As device infection increases, vendors also fail to release patches at a competitive pace. Despite security in IoT being an active area of research, prior work has mainly focused on vulnerability detection and exploitation, threat modelling, and protocol security. However, these methods are ineffective in preventing attacks against legacy and End-Of-Life devices that are already vulnerable. Current research mainly focuses on implementing and demonstrating the potential of malicious modifications. Hardening emerges as an effective solution to provide IoT devices with an additional layer of d…

IoTfirmware modificationcybersecurityend-of-lifesuojausSSL-proxyHTTPSlegacyfirmwaredefensive techniquesWAFretrofit securityesineiden internettietoturvakyberturvallisuusEOLverkkohyökkäyksetdeviceshaavoittuvuus
researchProduct