Search results for "Erythrocyte indices"
showing 10 items of 20 documents
Influence of inflammatory and lipidic parameters on red blood cell distribution width in a healthy population
2015
Red blood cell distribution width (RDW) is a routine red blood cell count parameter which has been shown to be associated with inflammatory parameters. Recently, some authors proposed that RDW seems to be a marker of an adverse lipidic profile. In order to clarify whether RDW is related to inflammation, plasma lipids, or both, we determined anthropometric, hematimetric, inflammatory and lipidic parameters in 1111 healthy subjects. RDW correlated directly with age, body mass index (BMI), inflammatory parameters (plasma viscosity, erythrocyte sedimentation rate (ESR), fibrinogen, leukocyte and neutrophil count), and inversely with iron and hematimetric parameters (P 0.05). When subjects were…
Rheological blood behaviour is not related to gender in morbidly obese subjects.
2012
To the Editor. We have read with interest the recently published article by Wiewiora et al. [7] regarding hemorheological differences related to gender in morbidly obese subjects. In this study authors found several hemorheological differences between male and female. In this sense, males showed higher blood viscosity and higher erythrocyte deformability than females and native blood viscosity correlated with several erythrocyte aggregation parameters evaluated with the Laser-Assisted Optical Rotational Cell Analyser (LORCA) [3]. In studies with small sample sizes (18 men and 20 women) there is always the risk that differences in certain variables may appear by chance or by imbalances in th…
Monocyte distribution width kinetic after surgery
2022
Not available
COVID-19 disease - Temporal analyses of complete blood count parameters over course of illness, and relationship to patient demographics and manageme…
2020
Background Detailed temporal analyses of complete (full) blood count (CBC) parameters, their evolution and relationship to patient age, gender, co-morbidities and management outcomes in survivors and non-survivors with COVID-19 disease, could identify prognostic clinical biomarkers. Methods From 29 January 2020 until 28 March 2020, we performed a longitudinal cohort study of COVID-19 inpatients at the Italian National Institute for Infectious Diseases, Rome, Italy. 9 CBC parameters were studied as continuous variables [neutrophils, lymphocytes, monocytes, platelets, mean platelet volume, red blood cell count, haemoglobin concentration, mean red blood cell volume and red blood cell distribu…
Markers of Anemia in Children with Type 1 Diabetes
2018
Aim. The aim of the study was to assess markers of anemia in type 1 diabetes (T1D) children, compare them to results obtained in the control group, and estimate their relation to BMI SDS. Methods. 94 (59% ♀) T1D children without other autoimmune disorders, aged 12.5 ± 4.1 years, T1D duration: 4.2 ± 3.6 years, HbA1c 7.3 ± 1.5% (57 ± 12.6 mmol/mol). Sex- and age-matched controls (43 children). In all children, anthropometric measurements, the blood count, iron turnover parameters, and vitamin B12 concentration were taken. Results. T1DM children had significantly higher red cell distribution width (RDW) (13.6 versus 12.6%; p<0.001), hepcidin (0.25 versus 0.12 ng/ml; p<0.001), and vitamin…
Association of erythrocyte deformability with red blood cell distribution width in metabolic diseases and thalassemia trait.
2016
Abstract Increased red blood distribution width (RDW) in anemia is related to disturbances in the cellular surface/volume ratio, usually accompanied by morphological alterations, while it has been shown in inflammatory diseases that the activity of pro-inflammatory cytokines disturbing erythropoiesis increases RDW. Recently it has been reported that higher RDW is related with decreased erythrocyte deformability, and that it could be related with the association of RDW and increased risk of cardiovascular diseases. In order to analyze the influence of morphological alterations and proinflammatory status on the relationship between RDW and erythrocyte deformability, we analyzed erythrocyte de…
Red blood cell distribution width: A simple parameter with multiple clinical applications
2014
The red blood cell distribution width (RDW) is a simple and inexpensive parameter, which reflects the degree of heterogeneity of erythrocyte volume (conventionally known as anisocytosis), and is traditionally used in laboratory hematology for differential diagnosis of anemias. Nonetheless, recent evidence attests that anisocytosis is commonplace in human disorders such as cardiovascular disease, venous thromboembolism, cancer, diabetes, community-acquired pneumonia, chronic obstructive pulmonary disease, liver and kidney failure, as well as in other acute or chronic conditions. Despite some demographic and analytical issues related to the routine assessment that may impair its clinical usef…
Amplitud de distribución eritrocitaria y riesgo de mortalidad en pacientes con insuficiencia cardiaca aguda
2013
Resumen Fundamento y objetivo El ancho de distribucion eritrocitaria (ADE) es una medida cuantitativa de la variabilidad del tamano de los eritrocitos circulantes utilizada clasicamente para el diagnostico diferencial de las anemias. En los ultimos anos, se ha sugerido que el ADE podria ser un marcador pronostico util en pacientes con insuficiencia cardiaca cronica. Sin embargo, es escasa la evidencia que respalda su papel en poblacion no seleccionada con insuficiencia cardiaca aguda (ICA), de manera independiente a los factores de riesgo establecidos. El objetivo del estudio fue establecer la asociacion entre el ADE y la mortalidad a largo plazo en pacientes ingresados por ICA. Pacientes y…
Early Biochemical and Hematological Response to Intramuscular Cyanocobalamin Therapy in Vitamin B<sub>12</sub>-Deficient Patients
2013
<b><i>Background:</i></b> Data on early biochemical and hematological responses to cobalamin therapy in vitamin B<sub>12</sub>-deficient patients are scarce. Therefore, we investigated whether cobalamin injections would include prompt biochemical and hematological responses in vitamin B<sub>12</sub>-deficient patients. <b><i>Subjects and Methods:</i></b> Seven female patients (mean age: 69.4 years, range: 61-78) with a mean serum cobalamin level of 104 ± 38 pmol/l mean ± SD and 7 male patients (mean age: 67.0 years, range: 53-78) with a mean serum cobalamin level of 84 ± 40 (±SD) participated in the study. They were adm…
Reply to "The association of red blood cell distribution width and morbid obesity" by Aydin et al.
2014
We thank Aydin & cols. for their comments about our recently published paper “Red blood cell distribution width is not related with inflammatory parameters in morbidly obese patients” in Clinical Biochemistry Journal [1]. The authors show their concern about the clinical interpretation of our findings since we did not report folate and B12 vitamin levels. Moreover, they state that we should demonstrate the elimination of thrombocytopenic diseases by showing platelet count data. Aswe state in the paper, exclusion criteria for obese patients included “organic, malignant, hematological, infectious or inflammatory disease”. Therefore, any case of thrombocytopenic disease was not included. Moreo…