Search results for "Esca"
showing 10 items of 966 documents
Delivery of Health Care by Spanish Dental Hygienists in Private and Public Dental Services during the COVID-19 De-Escalation Phase (June 2020): A Cro…
2021
Background: The first wave of the COVID-19 pandemic in Spain posed a major challenge for Spanish dental professionals. The objective of this work is to describe the dental hygienists’ work status and employment patterns during the de-escalation phase in order to analyse the standards of knowledge, compliance with official recommendations, and dental activities both in the public health service and in the private sector. Material and Methods: A cross-sectional questionnaire was answered by Spanish dental hygienists via WhatsApp, Facebook, and Instagram. The questionnaire was piloted before it was distributed and carried out during June 2020. Results: Here, 517 dental hygienists were surveyed…
Triple therapy de-escalation to dual bronchodilation in COPD patients: Baseline data from the DACCORD cohort
2020
Background: GOLD recommends triple therapy only in COPD patients with frequent exacerbations despite long-acting bronchodilators who exhibit a high blood eosinophil level (≥300/μL). Indication for ICS containing therapy should be reassessed regularly. Methods: The German real life study DACCORD included COPD patients who had received free triple therapy for ≥ 6 months prior to study entry. At baseline, patients were switched to LABA+LAMA fixed-dose combination (FDC) or maintained triple therapy upon discretion of the treating physician. Here, we compare baseline data of the 2 groups. Results: 1182 patients were recruited into DACCORD of which 30.7% were moved to LABA+LAMA FDC. Patients in t…
Assessment and management of agitation in psychiatry: Expert consensus
2016
International audience; BACKGROUND:Psychomotor agitation is associated with different psychiatric conditions and represents an important issue in psychiatry. Current recommendations on agitation in psychiatry are not univocal. Actually, an improper assessment and management may result in unnecessary coercive or sedative treatments. A thorough and balanced review plus an expert consensus can guide assessment and treatment decisions.METHODS:An expert task force iteratively developed consensus using the Delphi method. Initial survey items were based on systematic review of the literature. Subsequent surveys included new, re-worded or re-rated items.RESULTS:Out of 2175 papers assessing psychomo…
Preliminary study of the neuromuscular activation during barefoot and shod running
2015
El objetivo del presente estudio preliminar fue comparar la actividad muscular de los músculos tibial anterior, peroneo lateral largo, gastrocnemio medial y gastrocnemio lateral entre la carrera con y sin calzado, y la influencia de la fatiga. 7 participantes realizaron una carrera de fatiga de 20 minutos al 75% de su velocidad aeróbica máxima en cinta con 1% de pendiente. Se midió la actividad mioeléctrica de los músculos antes mencionados tanto antes como después de la prueba de fatiga en dos condiciones: con calzado y sin calzado. Los resultados mostraron una mayor actividad del tibial anterior durante la carrera en fatiga descalzo respecto a la carrera calzado y una mayor actividad del …
Natural Killer Group 2D Ligand Depletion Reconstitutes Natural Killer Cell Immunosurveillance of Head and Neck Squamous Cell Carcinoma
2017
Head and neck squamous cell carcinoma (HNSCC) is a highly heterogeneous and aggressive tumor originating from the epithelial lining of the upper aero-digestive tract accounting for 300,000 annual deaths worldwide due to failure of current therapies. The natural killer group 2D (NKG2D) receptors on natural killer (NK) cells and several T cell subsets play an important role for immunosurveillance of HNSCC and are thus targeted by tumor immune evasion strategies in particular by shedding of various NKG2D ligands (NKG2DLs). Based on plasma and tumor samples of 44 HNSCC patients, we found that despite compositional heterogeneity the total plasma level of NKG2DLs correlates with NK cell inhibitio…
Cancer-Initiating Cells from Colorectal Cancer Patients Escape from T Cell-Mediated Immunosurveillance In Vitro through Membrane-Bound IL-4
2014
Abstract Cancer-initiating cells (CICs) that are responsible for tumor initiation, propagation, and resistance to standard therapies have been isolated from human solid tumors, including colorectal cancer (CRC). The aim of this study was to obtain an immunological profile of CRC-derived CICs and to identify CIC-associated target molecules for T cell immunotherapy. We have isolated cells with CIC properties along with their putative non-CIC autologous counterparts from human primary CRC tissues. These CICs have been shown to display “tumor-initiating/stemness” properties, including the expression of CIC-associated markers (e.g., CD44, CD24, ALDH-1, EpCAM, Lgr5), multipotency, and tumorigenic…
Descartesin liikkeen filosofia : tutkielma Descartesin mekaniikasta ja siihen liittyvästä metafysiikasta
2011
Tämä tutkielma käsittelee Descartesin fysiikkaa ja etenkin kappaleiden liikettä sekä siihen liittyvää metafysiikkaa. Erityistä huomiota saavat Descartesin käsitykset matematiikasta, havainnosta ja yleisestä tieteenfilosofiasta sekä etenkin matematiikan ja todellisuuden suhteesta ja ne pyritään liittämään Descartesin kokonaiskuvaan ajasta, avaruudesta ja geometriasta.
I testi dell'analogia: introduzione alla prima edizione americana de L'architettura della città
2012
La tradizione dell’architetto-scrittore ha molti precedenti nella storia dell’architettura italiana. Dal Rinascimento all’Ottocento era caratteristica di certi architetti il presentare le loro idee in forma di trattati sistematici. Sul modello di Vitruvio, Alberti produsse il modello rinascimentale per tale tipo di scrittura. Fu seguito dalla trattatistica di Serlio e Palladio. Serlio compose una serie di volumi che costituirono veri e propri manuali per l’architettura, iniziando dall’edificio antico sino ad arrivare a riflessioni su lavori futuri non ancora realizzati. La rilevanza di tali progetti non costruiti, destinati a diventare più importanti dei modesti progetti effettivamente real…
Emanzipation und Manipulation. Zur Frage der deutschen Identität am Beispiel von zwei Bildunsgromanen: Wieland vs. Kolbenheyer.
2016
Der Beitrag untersucht die Genese des Bildungromans am Besipiel der Geschichte des Agathon (1766-67) von Ch. M. Wiekand, Genre par exellence der bürgerlichen Schichten des 18. Jh.s., die versuchen, sich zu emanzipieren. Dabei wurde am aufklärerischen Ideal der Perfektibilität des Einzelnen und der Gruppe festgehalten. Mit der Zeit schwindet der Glauben an die potentielle Perfektibilität. In manchen von der Forschung immerhin weiter so bezeichneten 'Bildungsromanen' dient die Ichwerdung weniger der Verbesserung des Einzelnen und der Gesellschaft, als vielmehr dem zutage Treten der Merkmale des 'Andersartigen'. Selten erfolgt die Manipulation des Genre krasser als in G. E. Kolbenheyers Trilog…
Le carriere universitarie degli studenti negli atenei statali e non statali in Italia
2020
Negli ultimi anni si è assistito ad un incremento della competizione tra gli atenei per “accaparrarsi” gli studenti, a cui si aggiunge una sempre maggiore attività di promozione e di reclutamento degli studenti delle università non statali (telematiche e non). Le università non statali, altrimenti denominate “libere Università”, sono promosse sia da enti di diritto privato che da enti pubblici (regioni, province, comuni). Esse sono legalmente riconosciute dal Ministero dell'Istruzione dell'Università e della Ricerca, e autorizzate a rilasciare titoli accademici, relativi all’ordinamento universitario, di valore legale identico a quelli rilasciati dalle università statali. La letteratura ha …