Search results for "Escala"
showing 10 items of 135 documents
Nine weeks versus 1 year adjuvant trastuzumab in combination with chemotherapy: final results of the phase III randomized Short-HER study
2018
Background: Chemotherapy plus 1-year trastuzumab is the standard adjuvant treatment of HER2-positive breast cancer. The efficacy of less extended trastuzumab exposure is under investigation. The short-HER study was aimed to assess the non-inferiority of 9 weeks versus 1 year of adjuvant trastuzumab combined with chemotherapy. Patients and methods: HER2-positive breast cancer patients with node-positive or, if node negative, with at least one risk factor (pT>2 cm, G3, lympho-vascular invasion, Ki-67 > 20%, age 35 years, or hormone receptor negativity) were randomly assigned to receive sequential anthracycline-taxane combinations plus 1-year trastuzumab (arm A, long) or plus 9 weeks tra…
First Interim Analysis of the Italian Dante Study: De-Escalation before Treatment-Free Remission in Patients with Chronic Myeloid Leukemia Treated wi…
2021
Abstract Introduction: Treatment-free remission (TFR) in chronic myeloid leukemia (CML) is demonstrated to be achievable and recommended for patients (pts) in sustained deep molecular response (sDMR) who can discontinue tyrosine kinase inhibitor (TKI) treatment and maintain responses in ~50% of cases. While the feasibility and safety of TKI cessation have been largely demonstrated, the strategies of TFR optimization are yet to be clarified. Studies (eg. DESTINY) investigating de-escalation, mainly after imatinib, suggested that a stepwise approach may favor TFR outcome. We present the interim results of the phase 2, prospective, multicenter DANTE study (NCT03874858) evaluating de-escalation…
Psychometric properties of the interaction on supervised classes scale (ISCS)
2016
Objeto: La presente investigación se centra en la construcción y validación de una escala diseñada para evaluar la calidad de la clases dirigidas: Escala de Interacción en las Clases Dirigidas (EICD). Diseño/metodología/enfoque: Se trata de un estudio descriptivo correlacional. Para la elaboración de la escala se recurrió a tres fases diferenciadas en las que diferentes expertos evaluaron la adecuación de los ítems, finalmente se estudiaron las propiedades psicométricas de la versión final en una muestra de 314 socios (69.1% mujeres) con edades entre los 18 y los 77 con una media de 39.33 años (DT=12.25). Aportaciones y resultados: La escala presenta una validez y fiabilidad adecuadas, sien…
The Work Design Questionnaire: Spanish version and validation
2015
The purpose of this study is to validate the Spanish version of the Work Design Questionnaire (WDQ; Morgeson & Humphrey, 2006). Employees from three Colombian samples completed the questionnaire (N = 831). Confirmatory factor analyses revealed a 21-factor structure ( 2 /df ratio = 2.40, SRMR = .06, RMSEA = .04, CFI = .90) with adequate levels of convergent and discriminant validity. Additional support for construct validity was found from significant differences among different occupational groups (professional and nonprofessional, health-focused, commercial, and manufacturing workers). Furthermore, knowledge, social, and work context characteristics showed incremental validity over tas…
Validation of the Working Alliance Inventory–Observer Short Version with male intimate partner violence offenders
2018
The working alliance is a key element to increase intimate partner violence (IPV) offenders' motivation, adherence to treatment, and active participation in batterer intervention programs (BIPs). The objective of the present study is to assess the psychometric properties and factor structure of the Working Alliance Inventory-Observer Short Version (WAI-O-S) with a sample of IPV offenders. The sample was 140 men convicted for IPV and court-mandated to a community-based BIP. Inter-rater agreement and reliability were evaluated by computing the intraclass correlation coefficient. To test the latent structure a Bayesian confirmatory factor analysis approach was used. To test criterion-related v…
Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure : the DIANA study
2020
© 2020 The Author(s).
Women's satisfaction with the experience of childbirth: validation of the Mackey Childbirth Satisfaction Rating Scale
2012
Objetivos: Determinar la fiabilidad y validez de contenido y concepto de la Mackey Childbirth Satisfaction Rating Scale, escala para medir la satisfacción de las mujeres con el parto y el nacimiento. Métodos: Se utilizó el método de traducción-retrotraducción para obtener una versión adaptada de la escala. Para la validación se seleccionó una muestra de 325 mujeres que habían tenido un hijo sano mediante parto vaginal. La recogida de datos se realizó con un cuestionario autocumplimentado que incluía la escala adaptada, expectativas ante el parto y variables obstétricas y sociodemográficas. Se valoró la fiabilidad en una submuestra de 45 mujeres que cumplimentaron de nuevo la escala a los 15…
Satisfacción de las mujeres con la experiencia del parto: validación de la Mackey Satisfaction Childbirth Rating Scale Women's satisfaction with the …
2012
Objetivos: Determinar la fiabilidad y validez de contenido y concepto de la Mackey Childbirth Satisfaction Rating Scale, escala para medir la satisfacción de las mujeres con el parto y el nacimiento. Métodos: Se utilizó el método de traducción-retrotraducción para obtener una versión adaptada de la escala. Para la validación se seleccionó una muestra de 325 mujeres que habían tenido un hijo sano mediante parto vaginal. La recogida de datos se realizó con un cuestionario autocumplimentado que incluía la escala adaptada, expectativas ante el parto y variables obstétricas y sociodemográficas. Se valoró la fiabilidad en una submuestra de 45 mujeres que cumplimentaron de nuevo la escala a los 15…
Research Letter: is neuroticism a risk factor for postpartum depression?
2012
Although the relationship between personality and depressive illness is complex (Shea, 2005), there is empirical evidence that some personality features such as neuroticism, harm avoidance, introversion, dependency, self-criticism or perfectionism are related to depressive illness risk (Gunderson et al. 1999). Moreover, personality traits, especially neuroticism, may explain the increased prevalence of depression among females (Goodwin & Gotlib, 2004). Few studies have explored neuroticism, extraversion and psychoticism as risk factors for depression after an event as stressful as childbirth. Pitt (1968) was the first author to report high scores on neuroticism and low scores on extraversio…
The Narcissistic Personality Inventory 8: Validation of a Brief Measure of Narcissistic Personality
2020
The present study was conducted with the aim of constructing and validating a short form of the Narcissistic Personality Inventory (NPI). The NPI is the most widely-applied measure for the assessment of narcissistic personality traits and, therefore, it is of great relevance for many research questions in personality and social psychology. To develop the short scale, we first found the optimal eight-item solution among all valid combinations of the NPI-15 items in an exploratory subsample (n = 1,165) of our complete representative sample of the German general population. We then validated this model in a confirmatory subsample (n = 1,126). Additionally, we examined its invariance across age…