Search results for "Essential"

showing 10 items of 812 documents

Volatile constituents of Scutellaria rubicunda Hornem subsp. linnaeana (Caruel) Rech. (Lamiaceae) endemic in Sicily

2006

PharmacologybiologyTraditional medicineCaryophylleneOrganic ChemistryVolatileScutellaria rubicunda HornemPharmaceutical Sciencebiology.organism_classificationBiochemistrylaw.inventionAnalytical Chemistrychemistry.chemical_compoundLinaloolchemistryComplementary and alternative medicinelawDrug DiscoveryBotanyScutellariaMolecular MedicineLamiaceaeSpodoptera littoralisEcology Evolution Behavior and SystematicsEssential oilPlanta Medica
researchProduct

Editorial: Management of Elevated Heart Rate in Essential Hypertension: Pathophysiological Insights and Therapeutic Approach.

2017

Pharmacologybusiness.industryPhysical activityPhysical activityDisease ManagementBlood PressureBioinformaticsEssential hypertensionmedicine.diseasePathophysiologyElevated heart rateTherapeutic approachHeart RateDrug DiscoveryMedicineAnimalsHumansEssential HypertensionbusinessCurrent pharmaceutical design
researchProduct

The Tolerability of Nilvadipine Compared to Nifedipine in Patients with Essential Hypertension

1992

In one multicenter, double-blind study, 659 hypertensive patients were treated for 16 weeks with either nilvadipine (n = 326) or nifedipine (n = 333). The major objective of the study was to compare the compatibility of the two calcium antagonists with regard to hepatic compatibility and side-effect profiles. The dosages were chosen so that the effective blood pressure reduction in both groups was equally good (mean decreases in systolic pressure of 27 +/- 12 mm Hg with nilvadipine and 26 +/- 15 mm Hg with nifedipine, and in diastolic pressure of 18 +/- 6 mm Hg with nilvadipine and 19 +/- 7 mm Hg with nifedipine). The mean heart rate was slightly lowered by about 2 beats/min by both substan…

Pharmacologybusiness.industryVasodilationEssential hypertensionmedicine.diseaseNilvadipineBlood pressureTolerabilityNifedipineAnesthesiaEdemaHeart ratemedicinemedicine.symptomCardiology and Cardiovascular Medicinebusinessmedicine.drugJournal of Cardiovascular Pharmacology
researchProduct

Analysis of Essential Oil from Teucrium maghrebinum Greuter et Burdet Growing Wild in Algeria

2009

The chemical composition of the essential oil obtained from aerial parts of Teucrium maghrebinum growing wild in Algeria was analyzed by GC and GC-MS. Among the 66 identified compounds, δ-cadinene (12.7%), germacrene D (11.4%), γ-cadinene (9.5%) and 4-vinyl guaiacol (4.0%) were the most abundant. The oil is strongly characterized by the presence of sesquiterpenes (61.5%), particularly hydrocarbon sesquiterpenes (49.6%).

Pharmacologychemistry.chemical_classificationbiologyChemistryPlant ScienceGeneral Medicinebiology.organism_classificationlaw.inventionTeucriumchemistry.chemical_compoundHydrocarbonComplementary and alternative medicinelawDrug DiscoveryBotanyLamiaceaeGuaiacolGas chromatography–mass spectrometryChemical compositionEssential oilGermacrene DNatural Product Communications
researchProduct

Chemical composition of the essential oils of Centaurea sicana and C. giardinae growing wild in Sicily

2008

The essential oils of Centaurea sicana (S) and C. giardinae (G) were studied by GC and GC-MS. Thirty constituents for S, representing 81.5% of the total oil, and 24 compounds for G (94.2% of the total) were identified. The oils were rich in sesquiterpenoids (47.9% for S and 54.7% for G) and hydrocarbons (25.9% for S and 31.7% for G). Germacrene D (13.3%), ( E)-β-farnesene (8.3%), nonacosane (7.3%), heptacosane (6.5%) and phytol (6%) were recognized as the main constituents for S, while caryophyllene oxide (17.7%), nonacosane (14.5%), germacrene D (11.5%), caryophyllene (11.2%) and heptacosane (10.3%) were the main compounds for G.

Pharmacologyfood.ingredientbiologyChemistryPlant ScienceGeneral MedicineAsteraceaebiology.organism_classificationSicanalaw.inventionfoodComplementary and alternative medicineCaryophyllene oxideCentaurealawDrug DiscoveryBotanyCentaurea giardinaeChemical compositionEssential oilGermacrene D
researchProduct

Long-term effects of lercanidipine on the lipoprotein and apolipoprotein profile of patients with mild-to-moderate essential hypertension

1999

Abstract The goal of this multicenter, randomized, double-masked, parallel- group study was to assess the effects of lercanidipine versus those of hydrochlorothiazide (HCTZ) on the lipoprotein and apolipoprotein profile of patients with mild-to-moderate essential hypertension. After a 2-week washout period, 52 patients (age range, 18 to 70 years) were randomly allocated to receive lercanidipine 10 mg (n = 26) or HCTZ 12.5 mg (n = 26) once a day for 24 weeks. In nonresponding patients, the dose was increased to 20 or 30 mg of lercanidipine once a day and to 25 or 37.5 mg of HCTZ once a day, after 4 and 8 weeks, respectively. To assess long-term effects, patients receiving lercanidipine enter…

Pharmacologymedicine.medical_specialtyTriglyceridebusiness.industryLercanidipinemedicine.medical_treatmentUrologyEssential hypertensionmedicine.diseasechemistry.chemical_compoundHydrochlorothiazideEndocrinologychemistryInternal medicineHeart ratemedicinePharmacology (medical)DiureticbusinessThiazidemedicine.drugLipoproteinCurrent Therapeutic Research
researchProduct

Evaluation of thrombin generation in classical Philadelphianegative myeloproliferative neoplasms / Evaluarea generării trombinei în neoplasmele mielo…

2016

Abstract Introduction: Patients with Philadelphia-negative chronic myeloproliferative neoplasms (Ph-MPN), polycytemia vera (PV), essential thrombocythaemia (ET) and primary myelofibrosis (PMF), are prone to develop thrombotic events. We aimed to investigate the coagulation status in their plasma using thrombin generation assay (TGA), a functional global assay, on Ceveron® Alpha. Materials and methods: The samples were collected from 89 consecutive Ph-negative MPN patients and from 78 controls into K2EDTA and CTAD tubes for blood cell counts, TGA and coagulation screening tests. Thrombin generation was analysed in platelet-poor plasma using Technothrombin® TGA assay kit. Results: We found a …

Philadelphia negativeessential thrombocythemiaidiopatic myelofibrosisbusiness.industryR030204 cardiovascular system & hematologyThrombin generation03 medical and health sciences0302 clinical medicinepolycythemia verahemic and lymphatic diseasesthrombin generationCancer researchMedicineMedicinebusinessthrombosis030215 immunologyRomanian Journal of Laboratory Medicine
researchProduct

A Review of the Phytochemistry, Traditional Uses and Biological Activities of the Essential Oils of Genus Teucrium

2020

AbstractThe genus Teucrium is a large and polymorphic genus of the Lamiaceae family distributed in mild climate zones, particularly in the Mediterranean basin and Central Asia. Studies of nonvolatile constituents of Teucrium species showed that they are a rich source of neo-clerodane diterpenoids, considered as chemotaxonomic markers of the genus. In addition to the nonvolatile metabolites, there has been a large interest in the essential oils of this genus. In this review, a complete survey of the chemical composition and biological properties of the essential oils isolated from Teucrium taxa is provided. In traditional medicine, since ancient times, species of this genus have been widely …

PhytochemistryPharmaceutical Science01 natural sciencesMediterranean BasinTeucriumAnalytical Chemistrylaw.inventionTeucriumGenuslawBiological propertyDrug DiscoveryBotanyOils VolatileEssential oilPharmacologyLamiaceaebiologyPlant Extracts010405 organic chemistryOrganic Chemistrybiology.organism_classification0104 chemical sciences010404 medicinal & biomolecular chemistryTaxonComplementary and alternative medicineTeucrium Lamiaceae ethnopharmacology essential oil biological propertiesMolecular MedicineLamiaceaeMedicine TraditionalPlanta Medica
researchProduct

The ethnobotany, phytochemistry and biological properties of genus Ferulago – A review

2020

Abstract Ethnopharmacological relevance The genus Ferulago, belonging to the Apiaceae family, is found mainly in the Mediterranean area, Southwest and Middle Asia, the Caucasus and North Africa. Since ancient times, species of this genus have been largely employed in traditional medicine for their biological properties such as antimicrobial, anti-inflammatory, antispasmodic, insecticidal, and anti-malaria, cholinesterase inhibition effects, etc. Aims The scope of this paper is to present a comprehensive respect review of this interesting genus including traditional uses, chemical composition of volatile and non-volatile metabolites, and in vitro and in vivo biological properties either util…

Phytochemistryfood.ingredientPhytochemicalsEthnobotanyApiaceae Bioactivity Essential oil Ferulago spp. Secondary metabolitesBiologylaw.inventionFerulago03 medical and health sciences0302 clinical medicinefoodGenuslawDrug DiscoveryAnimalsHumansSettore BIO/15 - Biologia FarmaceuticaEssential oil030304 developmental biologyPharmacology0303 health sciencesApiaceaeTraditional medicineSettore CHIM/06 - Chimica OrganicaAntimicrobialbiology.organism_classificationPhytochemical030220 oncology & carcinogenesisEthnobotanySettore BIO/03 - Botanica Ambientale E ApplicataMedicine TraditionalPlant PreparationsApiaceaeJournal of Ethnopharmacology
researchProduct

PHYTOTOXIC POTENTIAL OF EUCALYPTUS ESSENTIAL OILS FOR WEED CONTROL

2018

The widespread use of synthetic herbicides has resulted in herbicide-resistant weeds, disturbed ecological balance and negative effects on human health. Due to this fact, it is necessary to rely on alternative weed control strategies using natural compounds released by plants, such as essential oils (EOs). EOs have a short half-life since they are biodegradable, and are safer than synthetic compounds, with little damage to the environment, without even contaminating ground water (Topal and Kocaçalıskan 2006). Essential oils from different species contain allelochemical compounds that possess significant phytotoxic activity. Azizi and Fuji (2006) demonstrated that Eucalyptus (family Myrtacea…

Phytotoxicity Eucalyptus Essential oils weed control in VitroSettore AGR/13 - Chimica AgrariaPhytotoxicityEucalyptus Essential oilsweed controlin Vitro
researchProduct