Search results for "Ethology"

Differential effects of IL-10 on proliferation and cytokine production of human gamma/delta and alpha/beta T cells.

1994

Gamma/delta TCR bearing T lymphocytes represent a T-cell subset whose functional relevance remains unclear. Nevertheless these T cells may play a role in the early immune response against bacteria. Until now the regulatory mechanisms on this response have not been investigated. The study described here evaluated the immunoregulatory effects of Interleukin-10 on gamma/delta and alpha/beta TCR-positive T-cell clones and freshly isolated peripheral-blood mononuclear cells (PBMC). IL-10 has been shown previously to inhibit lectin and antigen-induced proliferation and cytokine production by alpha/beta T cells. The results outlined below show that rhIL-10 strongly inhibits lectin-induced producti…

The alpha and ßeta in phase II trials hepatocellular carcinoma ‐ A tale of more than radiological response?

2019

Agalsidase alpha and hearing in Fabry disease: data from the Fabry Outcome Survey.

2006

Fabry disease is an X-linked lysosomal storage disorder characterized by multi-organ dysfunction, including hearing loss - mainly sensorineural. The recent introduction of enzyme replacement therapy (ERT) has resulted in improvements in renal and cardiac function, pain and quality of life. One study has also suggested small improvements in high-frequency hearing. In this paper, we study the effect of ERT on hearing in patients in the Europe-wide database - the Fabry Outcome Survey (FOS). Twenty-six patients in FOS had pure-tone audiometry performed up to 6 months before starting ERT with agalsidase alpha and after a median of 12 months of treatment. We assessed changes in hearing thresholds…

Alpha- and gamma-interferon (IFNα, IFNγ) but not interleukin-1 (IL-1) modulate synthesis and secretion of β2-microglobulin by hepatocytes

1988

Soluble serum beta 2-microglobulin has been thought to result from membrane shedding by activated T-lymphocytes. This hypothesis could explain the increase of beta 2-microglobulin serum levels during virally induced mononucleosis, but not elevated levels as observed in other virally induced and in malignant diseases. In this paper we demonstrate that beta 2-microglobulin is a true secretory protein, and that its synthesis in hepatocytes is modulated by IFNs but not by IL-1. While the 45,000 MW HLA antigen can be found only in cell lysates, beta 2-microglobulin is shown to be secreted also into the culture medium like other secretory proteins (e.g. albumin-factor B-complement C3). Furthermor…

The $Q_{ \alpha}$-restriction problem

2019

2016

Current research demonstrates increased learning rates in differencial learning (DL) compared to repetitive training. To date, little is known on the underlying neurophysiological processes in DL that contribute to superior performance over repetitive practice. In the present study, we measured electroencephalographic (EEG) brain activation patterns after DL and repetitive badminton serve training. Twenty-four semi-professional badminton players performed badminton serves in a DL and repetitive training schedule in a within-subjects design. EEG activity was recorded from nineteen electrodes according to the 10-20 system before and immediately after each 20-minute exercise. Increased theta a…

Cardiac threat appraisal and depression after first myocardial infarction

2012

The present study investigated cardiac threat appraisal and its association with depression after first myocardial infarction (MI). A semi-structured interview allowing for DSM-IV-Axis I diagnoses was administered to 36 patients after first MI. Patients completed self-reports 5 to 15 days after the MI (time 1), 6 to 8 weeks later (time 2) and again 6 months later (time 3). Assessments at time 1 included indices of cardiac threat appraisal, locus of control, coping, and depression while at time 2 and time 3 only measures of depression were obtained. Cardiac threat appraisal was significantly correlated with depression at time 1, but was unrelated to depression scores at time 2 and time 3. Fu…

Non-linear dynamics of alpha and theta rhythm: correlation dimensions and Lyapunov exponents from healthy subject's spontaneous EEG.

1997

The aim of the present paper was to analyze some non-linear dynamic properties of the resting EEG from healthy subjects under eyes closed conditions. For this purpose we digitally filtered the spontaneous EEG in the theta (3-8 Hz) and alpha frequency range (8-13 Hz) and considered these independent rhythms as signals from a deterministic system. Under certain conditions non-linear dynamic systems are able to generate deterministic chaos, which means that similar causes do not produce similar effects. This phenomenon is called sensitive dependence on initial conditions. From different lead positions (F3, F4, Cz, P3, P4, O1 and O2) we calculated the so-called correlation dimension D2, which i…

Gender differences in the jealousy-evoking effect of rival characteristics

2011

This study examines gender differences in the jealousy-evoking nature of rival characteristics in two Spanish-speaking countries (Argentina and Spain). A total of 388 Spanish students and 444 Argentinean students participated in the study. First, the cross-cultural validity of a Dutch scale containing 56 rival characteristics was examined. A factor analysis distinguished four dimensions (i.e., social power and dominance, physical attractiveness, physical dominance, and social-communal attributes). After the analysis, the final scale contained in total 24 items. Results showed that in Argentina and Spain combined, men experienced more jealousy than women when their rival was more physically …

Evidence of the origin of specific spontaneous head turns during intertrial intervals.

1997

Direction and the frequency of spontaneous head movements during the ITIs following forward and backward paired trials were compared to an acquisition of a conditioned orienting (alpha) response directed to the side of the tone source. The head movements were analyzed from video recordings using classification of head turns to preferred and to nonpreferred directions. The results showed a significant increase in the alpha responses during the forward paired conditioning to the preferred direction and rapid extinction during the subsequent backward conditioning sessions. Spontaneous head movements during the ITIs increased to the same preferred direction as the conditioned alpha responses. T…