Search results for "Ethylene"
showing 10 items of 2589 documents
Buerger`s Disease and Hyperhomocysteinemia: Is there a Relationship?
2009
Thromboangiitis obliterans, also known as Buerger's disease, is a cause of juvenile lower limb ischaemia. Buerger's disease is idiopathic and one of diagnostic criteria is the absence of atherosclerotic risk factors other than smok- ing. A possible involvement of thrombophilia has been investigated and the role of hyperhomocysteinemia is still matter of discussion. We describe 9 patients with Buerger's disease followed-up for the past 3 years. We found a significant in- crease in circulating homocysteine levels (mean: 31.6 in patients vs 8.2 μmol/L in control subjects). We also analyzed the C677T mutation of MTHFR; 5/9 Buerger's patients were heterozygotes and 4/9 homozygotes for the mutati…
Gelchromatographie. 6. Mitt. trennungen im präparativen maßstab mit hoher auflösung
1968
Zur gelchromatographischen Trennung im Grammengen-Bereich wurde ein Recycling-Verfahren mit kontinuierlicher Einengung des Eluates entwickelt. Die Trennung von Oligomeren des Styrols, des Butylmethacrylates und des Athylenoxids unter Anwendung dieser Methode wire beschrieben. Vorteile und Grenzen des Verfahrens werden diskutiert. A recycling technic with continuous concentration of the eluate has been developed for gel chromatographic separation in the gram-scale. The separation of oligomers of styrene, butyl methacrylate and ethylene oxide by use of this method is described. Advantages and limitation of this procedure are discussed.
Antibodies against tumor necrosis factor (TNF) induce T-cell apoptosis in patients with inflammatory bowel diseases via TNF receptor 2 and intestinal…
2011
Background & Aims The anti–tumor necrosis factor (TNF) antibodies infliximab, adalimumab, and certolizumab pegol have proven clinical efficacy in Crohn's disease. Here, we assessed the effects of anti-TNF antibodies on apoptosis in inflammatory bowel disease (IBD). Methods CD14 + macrophages and CD4 + T cells were isolated from peripheral blood and lamina propria mononuclear cells from patients with IBD and control patients. Cell surface markers and apoptosis were assessed by immunohistology and fluorescence-activated cell sorting techniques. Results Lamina propria CD14 + macrophages showed significantly more frequent and higher membrane-bound TNF (mTNF) expression than CD4 + T cells in IBD…
TyG index, HOMA score and viral load in patients with chronic hepatitis C due to genotype 1.
2011
Summary. The triglycerides × glucose (TyG) index is a recently proposed surrogate marker of insulin resistance (IR), calculated from fasting plasma triglyceride and glucose concentrations. We tested the host and viral factors associated with Tyg and homeostasis model assessment (HOMA) scores, comparing their associations with histological features and with sustained virological response (SVR) in patients with genotype 1 chronic hepatitis C(G1CHC). Three hundred and forty consecutive patients with G1CHC were considered. All had a liver biopsy scored by one pathologist for staging and grading (Scheuer), and graded for steatosis, which was considered moderate–severe if ≥30%. Anthropometric an…
Spectroscopic, crystal structural, theoretical and biological studies of phenylacetohydrazide Schiff base derivatives and their copper complexes
2020
Two phenylacetohydrazide Schiff base derivatives: N’-(1-(2-hydroxyphenyl)ethylidene)-2-phenylacetohydrazide, HL1, and N’-((1-hydroxynaphthalen-2-yl)methylene)-2-phenylacetohydrazide, HL2, were synthesized. HL1 dimerizes in presence of HCl, probably via radical mechanism to give (2,2’-((1E)-hydrazine-1,2-diylidenebis(ethan-1-yl-1-ylidene))diphenol (DIM). Thermal reactions of Cu(II) ions with the two Schiff base ligands resulted in formation of the binuclear complexes [(CuL1)2] and [(CuL2)2]. The stoichiometry and structures of the reported compounds were investigated by several spectroscopic and analytical techniques. The structure of the HL1 ligand and its complex [(CuL1)2] as well as the D…
Non-pegylated liposomal doxorubicin plus cyclophosphamide as first-line therapy in elderly women with HER2 negative metastatic breast cancer.
2022
Background. The use of anthracyclines in metastatic breast cancer (MBC) is limited by cumulative dose-dependent cardiotoxicity mostly in elderly women with comorbidities. The aim of this observational retrospective study was to evaluate the efficacy of non-pegylated liposomal doxorubicin (Myocet®) and cyclophosphamide in elderly women as HER2 negative first-line MBC treatment. Methods. 84 elderly women >70 years of age (median age 78 years) with MBC HER2 negative were enrolled. Performance Status in 58 patients was ECOG-0 and in 26 patients was ECOG-1. Results. The drug was well tolerated, with overall response rates were >40%, median overall survival was 16.2 months (95%CI:14.6- 18.8…
Chemical speciation of nucleotide 5′-monophosphates in the presence of biogenic amines
2001
The interaction of adenosine-, uridine-, inosine- and guanosine-5’-monophosphates with protonated ethylenediamine, putrescine, cadaverine, spermidine and spermine, was studied potentiometrically, a...
Interactions of Dioxouranium(VI) with Amines in Aqueous Solution
2010
The interaction of the dioxouranium(VI) ion with five low molecular weight polyamines (ethylenediamine, putrescine, cadaverine, spermidine, and spermine) and with poly(allyl)amine (15 kDa) was studied potentiometrically (ISE-H + glass electrode) at T ) 298.15 K. Investigations were carried out in NaNO3 ionic medium, at I ) 0.1 mol · L -1 (and 0.5 mol · L -1 for poly(allyl)amine only), in the pH range 3.5 to 5.5, before the formation of uranyl insoluble species. The results gave evidence for the formation of two species, namely, UO2L 2+ and UO2L(OH) + for the diamine systems (ethylenediamine, putrescine, cadaverine), UO2L 2+ and UO2LH 3+ for spermidine, and UO2LH 3+ and UO2LH2 4+ for spermin…
Rheological and Mechanical Behavior of LDPE/Calcium Carbonate Nanocomposites and Microcomposites
2012
The increase of the interest in polymer nanocomposites has been leading to continuous growing search toward nanofillers alternative to the widely known clay-based ones. One of these possible alternatives is represented by calcium carbonate nanoparticles, which have not been widely investigated in such context. In this article, a study on the rheological and morphological behavior of dif- ferent low density polyethylene-calcium carbonate nanocomposites, compared with a reference calcium carbonate microcomposite, is presented. Several different nanosized calcium carbonates at different amounts were used. The results from the rheological and me- chanical tests outlined that only minor changes …
Amorphous Calcium Phosphates: Solvent-Controlled Growth and Stabilization through the Epoxide Route.
2020
Calcium phosphates stand among the most promising nanobiomaterials in key biomedical applications, such as bone repairment, signalling or drug/gene delivery. Their intrinsic properties as crystalline structure, composition, particle shape and size define their successful use. Among these compounds, metastable amorphous calcium phosphate (ACP) is currently gaining particular attention due to its inherently high reactivity in solution, which is crucial in bone development mechanisms. However, the preparation of this highly desired (bio)material with control over its shape, size and phase purity remains as a synthetic challenge. In this work, the epoxide route was adapted for the synthesis of …