Search results for "Eugen"

Assessment of mechanisms driving non-linear dose-response relationships in genotoxicity testing.

2014

In genetic toxicology, risk assessment has traditionally adopted linear dose-responses for any compound that causes genotoxic effects. Increasing evidence of non-linear dose-responses, however, suggests potential cellular tolerance to low levels of many genotoxicants with diverse modes of action. Such putative non-linear dose-responses need to be substantiated by strong mechanistic data that identifies the mechanisms responsible for the tolerance to low doses. This can be achieved by experimental demonstration of cytoprotective mechanisms and by providing experimental support for the existence of tolerance mechanisms against low dose effects. By highlighting key experiments into low dose me…

Wesley Clair Mitchell and the “Illiberal Reformers”: A Documentary Note

2021

In this note we inquire whether Mitchell as a reformer ever expressed concern over the biological quality of individuals and whether he did somehow share the Progressive Era faith in eugenics as an instrument for improving American society’s health, welfare, and morals. This is an aspect of Mitchell’s thought that has received scant attention in the literature and that projects him into the current debate on progressivism.

Biological properties of a biomaterial obtained from Syzygium aromaticum

2019

Studies performed on Essential oil of Syzygium aromaticum (EOSa) from the Romanian market indicate a relative content of 73.18% in Eugenol. Due to this compound, the antioxidant activity determined...

Architetture esemplari

2018

Nel ripercorrere le vicende dell’architettura durante il ventennio fascista nella città di Trapani, attraverso il ridisegno di due architetture esemplari — la casa del Balilla di Emanuele Filiberto Paolini e la casa del Mutilato di Giuseppe Eugenio Genovese — Salvatore Damiano prova a mettere a fuoco il percorso evolutivo che si determina nella piccola, ma antica, realtà urbana siciliana, nei due decenni di vita del regime fascista, sia sul piano istituzionale, sia su quello ideologico– culturale. Trapani, agli inizi del secondo decennio, come il resto delle città siciliane, è ancora intrisa della stagione del modernismo e di un eclettico e tradizionalista conformismo culturale post umberti…

Design and synthesis of biobased epoxy thermosets from biorenewable resources

2017

International audience; Biobased diepoxy synthons derived from isoeugenol, eugenol or resorcinol (DGE-isoEu, DGE-Eu and DGER, respectively) have been used as epoxy monomers in replacement of the diglycidyl ether of bisphenol A (DGEBA). Their curing with six different biobased anhydride hardeners leads to fully biobased epoxy thermosets. These materials exhibit interesting thermal and mechanical properties comparable to those obtained with conventional petrosourced DGEBA-based epoxy resins cured in similar conditions. In particular, a high Tg in the range of 90–130 °C and instantaneous moduli higher than 4.3 GPa have been recorded. These good performances are very encouraging, making these n…

SOCIAL STRATIFICATION, HEREDITARIANISM, AND EUGENICS. A HARVARD TALE

2019

This chapter documents how eugenics, scientific racism, and hereditarianism survived at Harvard well into the interwar years. In the late 1920s and early 1930s, Thomas Nixon Carver and Frank W. Taussig published works in which they established a close nexus between an individual’s economic position and his biological fitness. Carver, writing in 1929, argued that social class rigidities are attributable to the inheritance of superior and inferior abilities on the respective social class levels and proposed an “economic test of fitness” as a eugenic criterion to distinguish worthy from unworthy individuals. In 1932, Taussig, together with Carl Smith Joslyn, published American Business Leaders…

Chemical Constituents ofGynura cusimbuaAerial Parts

2007

Abstract The essential oil isolated from the aerial parts of Gynura cusimbua was analyzed by GC and GC/MS. Forty-seven constituents totaling 91.92% of the oil were identified. The major constituents of the oil are myrcene (31.0%), β- phellandrene (12.43%), eugenol (6.34%), α-humulene (6.20%), dodecyl acrylate (6.09%), α-copaene (5.61%), phytol (3.21%), germacrene D (3.0%), cryptone (2.04%), 2,4-ditertbutylphenol (1.62%), α-pinene (1.33%), α-cadinene (1.26%), caryophyllene oxide (1.24%) and β-caryophyllene (1.08%).

The effect of clove oil sedation on oxygen consumption of six temperate-zone fish species

2004

Sexualidad, reproducción y cultura obrera revolucionaria en España: la revista <em>Orto</em> (1932-1934)

2014

Orto. Revista de Documentacion Social, published in Valencia from 1932 to 1934, is a good example of cultural magazines in the Spanish labour movement, particularly in the world of anarcho-syndicalism. Marin Civera, its editor, sought to make Orto (which had a large and diverse range of contributors) a forum for convergence between the different working-class ideologies, united by the ideas of “Syndicalism”. In keeping with its aim to be “social documentation for the proletariat “, the journal took a strong interest in the spread of theory and practice, and debates on, sexual reform, linking these efforts to the international movement for that cause. In addition to the struggle for a new se…

Cisplatin-induced endoreduplication in CHO cells: DNA damage and inhibition of topoisomerase II.

2006

It has been proposed that polyploid cells that arise during a variety of pathological conditions and as a result of exposure to genotoxicants, typically in the liver, become aneuploid through genetic instability. Aneuploidy contributes to, or even drives, tumour development. We have assessed the capacity of the drug cisplatin, one of the most commonly used compounds for the treatment of malignancies, to induce endoreduplication, a particular type of polyploidy, in cultured Chinese hamster AA8 cells. Taking into account that any interference with DNA topoisomerase II (topo II) function leads to endoreduplication, we have found that treatment of the cells with this platinum compound results i…