Search results for "Eva"

Ramírez Aledón, Germán: La Ilustración católica ante la crisis del Antiguo Régimen en España. Joaquín Lorenzo Villanueva y Astengo

2021

Applying System Dynamics Modelling to Strategic Management: A Literature Review

2016

System dynamics (SD) has been proved to be a useful methodology to support both understanding and learning processes of complex systems and phenomena. Since its origin, SD has been successfully applied to many different fields of studies (e.g. climate change, physics, engineering, environmental sciences, economics, management, etc.). Among these, strategic management (SM) has a particular relevance as testified by several streams of research that originate from the combination between SD modelling and SM. The aim of this paper is to explore and discuss the theoretical and empirical development of SD in the SM field through a systematic analysis of the literature in order to highlight the ma…

Watermarking for ontologies

2011

In this paper, we study watermarking methods to prove the ownership of an ontology. Different from existing approaches, we propose to watermark not by altering existing statements, but by removing them. Thereby, our approach does not introduce false statements into the ontology. We show how ownership of ontologies can be established with provably tight probability bounds, even if only parts of the ontology are being re-used. We finally demonstrate the viability of our approach on real-world ontologies.

Automatic Integration of Spatial Data into the Semantic Web

2017

International audience

Biological and physical modification of carbonate system parameters along the salinity gradient in shallow hypersaline solar salterns in Trapani, Ita…

2017

Abstract We investigated changes in the chemical characteristics of evaporating seawater under the influence of microbial activity by conducting geochemical analyses of the brines and evaporite sediments collected from solar salterns in Trapani, Italy. The microbial activity had a substantial effect on the carbonate system parameters. Dissolved inorganic carbon (DIC) was substantially removed from the brine during the course of evaporation from the seawater to the point where calcium carbonate precipitates, with an accompanying decrease in its carbon isotopic composition (δ 13 C DIC ) to as low as −10.6‰. Although the removal of DIC was due to calcium carbonate precipitation, photosynthesis…

Aproximaciones para mejorar el crecimiento de bacterias lácticas iniciadoras OM13 durante las primeras etapas de producción de aceitunas verdes de me…

2018

The present research aimed at determining the optimal conditions for the lactic acid fermentation of green Spanish-style table olives. The work is a follow-up, and focuses on the performance of the commercial starter strain Lactobacillus pentosus OM13 by applying an acclimatization step and the addition of nutrients, and concentrations of lactic acid that were previously investigated. The acclimatization of the cells warranted the dominance of the starter culture even at an inoculation level of 2 Log cycles lower than that commonly used in standard fermentation. A significant effect was found in terms of acidification kinetics within the first week of fermentation, with the highest decrease…

Adolescents’ food packaging perceptions. Does gender matter when weight control and health motivations are considered?

2016

Abstract This paper investigates, first, to what extent adolescents highly involved in food are more worried about weight control and health than less involved adolescents. Second, it studies the impact of both food choice motivations on food packaging relevance, considering both, visual and informative packaging cues. Finally, these relationships are re-tested in two different frameworks: men and to this end, 589 adolescent consumers between 14 and 17 years were questioned. The interviews were done personally by an external company at the door of 30 different schools. Our results have confirmed the relevance of packaging informative cues over visual cues for adolescents highly worried abou…

Phosphorylation of CENP-A on serine 7 does not control centromere function.

2019

CENP-A is the histone H3 variant necessary to specify the location of all eukaryotic centromeres via its CENP-A targeting domain and either one of its terminal regions. In humans, several post-translational modifications occur on CENP-A, but their role in centromere function remains controversial. One of these modifications of CENP-A, phosphorylation on serine 7, has been proposed to control centromere assembly and function. Here, using gene targeting at both endogenous CENP-A alleles and gene replacement in human cells, we demonstrate that a CENP-A variant that cannot be phosphorylated at serine 7 maintains correct CENP-C recruitment, faithful chromosome segregation and long-term cell viab…

Indicaxanthin from Opuntia Ficus Indica (L. Mill) impairs melanoma cell proliferation, invasiveness, and tumor progression.

2018

Abstract Background: A strong, reciprocal crosstalk between inflammation and melanoma has rigorously been demonstrated in recent years, showing how crucial is a pro-inflammatory microenvironment to drive therapy resistance and metastasis. Purpose: We investigated on the effects of Indicaxanthin, a novel, anti-inflammatory and bioavailable phytochemical from Opuntia Ficus Indica fruits, against human melanoma both in vitro and in vivo. Study Design and Methods: The effects of indicaxanthin were evaluated against the proliferation of A375 human melanoma cell line and in a mice model of cutaneous melanoma. Cell proliferation was assessed by MTT assay, apoptosis by Annexin V-Fluorescein Isothio…

Autosomal recessive hypercholesterolemia in Spain.

2017

Abstract Background and aims Autosomal recessive hypercholesterolemia (ARH) is a very rare disease, caused by mutations in LDL protein receptor adaptor 1 (LDLRAP1). It is characterized by high levels of low-density lipoprotein cholesterol (LDL-C) and increased risk of premature cardiovascular disease. We aimed to characterize ARH in Spain. Methods Data were collected from the Dyslipidemia Registry of the Spanish Atherosclerosis Society. A literature search was performed up to June 2017, and all diagnostic genetic studies for familial hypercholesterolemia of Spain were reviewed. Results Seven patients with ARH were identified, 6 true homozygous and one compound heterozygous with a novel muta…