Search results for "ExAC"
showing 10 items of 1440 documents
The impact of grouping patients by the 2017 GOLD COPD strategy on response to therapy: post hoc results from the TONADO tiotropium+olodaterol trials
2017
Introduction: In the 2017 GOLD COPD strategy the classification of patients by assessment of symptoms and history of exacerbation is used to guide treatment choices. The previous strategy also included lung function. Aims and objectives: To investigate the effect of the 2017 classification on an analysis of the efficacy of tiotropium+olodaterol (T+O) in GOLD stage A/B patients with COPD. Methods: Patients from the Phase III, replicate 52-week TONADO studies (NCT01431274, NCT01431287), who received T+O or the mono-components, were classed as GOLD A/B or C/D by the 2017 strategy (using exacerbation history) or 2014 strategy (using lung function and exacerbation history). Since mMRC Dyspnoea S…
Magnetic Resonance Imaging Derived Biomarkers of IDH Mutation Status and Overall Survival in Grade III Astrocytomas
2020
The evaluation of the isocitrate dehydrogenase (IDH) mutation status in the glioma decision-making process has diagnostic, prognostic and therapeutic implications. The aim of this study was to evaluate whether conventional magnetic resonance imaging (MRI) and apparent diffusion coefficient (ADC) can noninvasively predict the most common IDH mutational status (R132H) in GIII-astrocytomas and the overall survival (OS). Hence, twenty-two patients (9-F, 13-M) with a histological diagnosis of GIII-astrocytoma and evaluation of IDH-mutation status (12-wild type, 10-mutant) were retrospectively evaluated. Imaging studies were reviewed for the morphological feature and mean ADC values (ADCm). Stati…
Is telephone follow-up useful in preventing post-extraction bleeding in patients on antithrombotic treatment?
2021
Background The aim of the study was to investigate the usefulness of telephone follow-up in preventing post-extraction bleeding and improving wound healing in patients on chronic antithrombotic treatment. Material and methods A prospective randomized clinical trial was carried out on 256 patients (test group = 128; control group = 128). The exact two-tailed Fisher test and the two-tailed non-parametric Mann-Whitney test were used for statistical analysis. Results The incidence of post-extraction bleeding was 15.6% and there was no difference between test and control groups. However, the study group was significantly, though weakly, associated with the severity of bleeding. Patient satisfact…
An Exact Solution for the Level-Crossing Rate and the Average Duration of Fades of the Envelope of Sum-of-Cisoids Processes
2012
Authors version of an article published in the journal: Procedia Technology. Also available from the publisher at: http://dx.doi.org/10.1016/j.protcy.2012.03.004 Sum-of-cisoids (SOC) processes provide a physically and numerically appealing framework for the modelling and simulation of a wide class of mobile radio channels. This paper is concerned with the problem of finding a general solution for the level-crossing rate (LCR) and the average duration of fades (ADF) of the envelope of SOC processes. Exact expressions are derived for the LCR and the ADF by taking into account that the inphase component, the quadrature component, and the time derivatives of the inphase and quadrature component…
Wstępna ocena właściwości psychometrycznych skal MOTIVE8 i PERSONALITY6
2019
Celem opracowania jest analiza właściwości psychometrycznych narzędzi do pomiaru osobowości – Personality6 oraz motywacji – Motive8. Testy opierają się na koncepcji osobowości HEXACO1 oraz motywacji – osiągnięć2, teorii autoregulacji3 oraz koncepcji flow 4. Badania przeprowadzono łącznie na grupie 406 osób.
Design and implementation of the AMIGA embedded system for data acquisition
2021
The successful installation, commissioning, and operation of the Pierre Auger Observatory would not have been possible without the strong commitment and effort from the technical and admin-istrative staff in Malargtie. We are very grateful to the following agencies and organizations for financial support: Comision Nacional de Energla Atomica, Agencia Nacional de Promocion Cientffica y Tec-nologica (ANPCyT) , Consejo Nacional de Investigaciones Cientfficas y Tecnicas (CONICET) , Gobierno de la Provincia de Mendoza, Municipalidad de Malargtie, NDM Holdings and Valle Las Leilas, in gratitude for their continuing cooperation over land access, Argentina; the Australian Research Council; Conselho…
Comparison of frictional resistance between passive self-ligating brackets and slide-type low-friction ligature brackets during the alignment and lev…
2019
Background To compare the frictional resistance between passive self-ligating brackets and conventional brackets with low-friction ligature under bracket/archwire and root/bone interface during dental alignment and leveling. Material and methods A tridimensional model of the maxilla and teeth of a patient treated with conventional brackets, and slide ligatures was generated employing the SolidWorks modeling software. SmartClip self-ligating brackets and Logic Line conventional brackets were assembled with slide low-friction ligatures, utilizing archwires with different diameters and alloys used for the alignment and leveling stage. Friction caused during the bracket/archwire interface and s…
Biharmonic obstacle problem: guaranteed and computable error bounds for approximate solutions
2020
The paper is concerned with a free boundary problem generated by the biharmonic operator and an obstacle. The main goal is to deduce a fully guaranteed upper bound of the difference between the exact minimizer u and any function (approximation) from the corresponding energy class (which consists of the functions in $H^2$ satisfying the prescribed boundary conditions and the restrictions stipulated by the obstacle). For this purpose we use the duality method of the calculus of variations and general type error identities earlier derived for a wide class of convex variational problems. By this method, we define a combined primal--dual measure of error. It contains four terms of different natu…