Search results for "ExAC"
showing 10 items of 1440 documents
CCDC 902683: Experimental Crystal Structure Determination
2013
Related Article: Yu Chen, Derong Cao, Lingyun Wang, Minqing He, Lixia Zhou, Dieter Schollmeyer, Herbert Meier|2013|Chem.-Eur.J.|19|7064|doi:10.1002/chem.201204628
On the complexity of the Saccharomyces bayanus taxon: Hybridization and potential hybrid speciation
2014
Although the genus Saccharomyces has been thoroughly studied, some species in the genus has not yet been accurately resolved; an example is S. bayanus, a taxon that includes genetically diverse lineages of pure and hybrid strains. This diversity makes the assignation and classification of strains belonging to this species unclear and controversial. They have been subdivided by some authors into two varieties (bayanus and uvarum), which have been raised to the species level by others. In this work, we evaluate the complexity of 46 different strains included in the S. bayanus taxon by means of PCR-RFLP analysis and by sequencing of 34 gene regions and one mitochondrial gene. Using the sequenc…
Staru terapijas pacientu ar galvas smadzeņu audzējiem pozicionēšanas precizitātes novērtējums, izmantojot ExacTrac sistēmu
2017
Bakalaura darba tēma – Staru terapijas pacientu ar galvas smadzeņu audzējiem pozicionēšanas precizitātes novērtējums, izmantojot Exactrac® sistēmu. Tēmas aktualitāti nosaka onkoloģisko saslimstību pieaugums un pieejamo staru terapijas tehnoloģiju lietderība ikdienas ārstēšanas kvalitātes uzlabošanā. Darba mērķis ir noteikt faktorus, kas ietekmē pacientu pozicionēšanas precizitāti un noskaidrot to cēloņus. Pētniecības uzdevumi ir veikt datu protokolēšanu, veikt datu apstrādi un analīzi, izvirzīt secinājumus, analizēt literatūras avotus un salīdzināt to rezultātus ar pētījumā iegūtajiem. Izvirzīta hipotēze – pozicionēšanu precizitāti ietekmē dažādas etioloģijas faktoru kopums. Pētniecības ins…
The Influence of Microbiome Dysbiosis and Bacterial Biofilms on Epidermal Barrier Function in Atopic Dermatitis—An Update
2021
Atopic dermatitis (AD) is a common inflammatory dermatosis affecting up to 30% of children and 10% of adults worldwide. AD is primarily driven by an epidermal barrier defect which triggers immune dysregulation within the skin. According to recent research such phenomena are closely related to the microbial dysbiosis of the skin. There is growing evidence that cutaneous microbiota and bacterial biofilms negatively affect skin barrier function, contributing to the onset and exacerbation of AD. This review summarizes the latest data on the mechanisms leading to microbiome dysbiosis and biofilm formation in AD, and the influence of these phenomena on skin barrier function.
Global Initiative for Asthma (GINA) Strategy 2021 - Executive summary and rationale for key changes
2021
Funder: Global Initiative for Asthma
LABA/LAMA fixed-dose combinations in patients with COPD: A systematic review
2018
Paola Rogliani,1 Luigino Calzetta,1 Fulvio Braido,2 Mario Cazzola,1 Enrico Clini,3 Girolamo Pelaia,4 Andrea Rossi,5 Nicola Scichilone,6 Fabiano Di Marco7 1Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Rome, Italy; 2Department of Internal Medicine, IRCCS San Martino Genoa University Hospital, Genoa, Italy; 3Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy; 4Department of Medical and Surgical Sciences, Section of Respiratory Diseases, Magna Græcia University, Catanzaro, Italy; 5Pulmonary Unit, University of Verona, Verona, Italy; 6Department of Internal Medicine, University of Palermo, Palermo, Italy; 7…
Breakthrough Pain (BTP) in Opioid-Tolerant Cancer Patients: A Pan-European Open-Label Multicentre Study with Fentanyl Buccal Tablet (FBT)
2012
ABSTRACT BTP, a transitory exacerbation of pain that occurs on a background of otherwise controlled persistent pain, is a common problem in cancer patients. FBT is indicated for the treatment of BTP in adults with cancer already receiving maintenance opioid therapy for chronic cancer pain and should be titrated to an effective dose that provides adequate analgesia and minimises undesirable events. In this study, patients entered a screening period and were randomized during an open-label titration period to a starting FBT dose of 100 µg (group A) or 200 µg (group B) to identify the FBT effective dose and then treated in an open-label period (for 8 BTP episodes). Patients' inclusion followed…
Correlation between HHV-6 reactivation and multiple sclerosis disease activity.
2002
This study examined the association between HHV-6 infection and multiple sclerosis (MS) and the relationship between HHV-6 reactivation and disease activity. The frequency of HHV-6 genomic sequences in peripheral blood mononuclear cells (PBMCs), the incidence of plasma viremia (nPCR), the transcription of viral mRNA in PBMCs (RT-PCR), the presence of antiviral IgM and IgG class antibodies in the plasma (IFA) of 16 relapsing/remitting and secondary progressive MS patients were studied in comparison with clinical manifestations of the disease, magnetic resonance imaging (MRI) of brain, and serum interleukin (IL)-12 concentrations (ELISA). The prevalence of HHV-6 infection was significantly hi…
INTERFACE TENSION AND CORRELATION LENGTH OF 2D POTTS MODELS: NUMERICAL VERSUS EXACT RESULTS
1994
I briefly review new analytical formulas for the correlation length and interface tension of two-dimensional q-state Potts models and compare them with numerical results from recent Monte Carlo simulation studies.
A Push Forward Construction and the Comprehensive Factorization for Internal Crossed Modules
2014
In a semi-abelian category, we give a categorical construction of the push forward of an internal pre-crossed module, generalizing the pushout of a short exact sequence in abelian categories. The main properties of the push forward are discussed. A simplified version is given for action accessible categories, providing examples in the categories of rings and Lie algebras. We show that push forwards can be used to obtain the crossed module version of the comprehensive factorization for internal groupoids.