Search results for "Exam"
showing 10 items of 1241 documents
Serum eosinophil cationic protein as a potential biomarker for interleukin-5 antibody treatment in patients with severe uncontrolled eosinophilic ast…
2018
Serum eosinophil cationic protein (ECP) has been described as a marker reflecting activation of eosinophils in asthma, potentially correlating to airway inflammation. Our aim was to examine the role of serum ECP to predict treatment efficacy in asthmatics starting interleukin-5 antibody (anti-IL5) therapy. We evaluated 65 patients with severe, uncontrolled eosinophilic asthma (≥300 eosinophils per µl blood) before and approx. 4 months after initiation of anti-IL5 therapy with mepolizumab; 35 patients completed a 12 month follow-up. Evaluation of treatment efficacy included medical history, asthma questionnaires, physical examination, spirometry, exhaled NO and blood tests. Depending on the …
A 15-Year-Old Boy with Anterior Chest Pain, Progressive Dyspnea, and Subcutaneous Emphysema of the Neck
2009
We describe the case of an adolescent who was admitted to the hospital because of sudden occurrence of chest pain, dyspnea and subcutaneous emphysema. On admission, physical examination revealed subcutaneous crepitations in the superior part of the rib cage, and auscultation of the chest showed widespread wheezing. The radiological assessment confirmed the diagnosis of pneumomediastinum and pneumothorax. A follow-up CT scan performed one week after the admission showed almost complete resolution of the radiological alterations. At the following visits, the patient was asymptomatic, but reported to have suffered from frequent episodes of rhinorrea, sneezing, nasal blockage, and sometimes, ch…
Preparation for Endoscopic Examination
1979
Inspection of the perianal area, the digital rectal examination, and the proctoscopic examination may be done without special preparation.
La mobilità volontaria nel Pubblico Impiego: margini di discrezionalità dell'Amministrazione di destinazione
2022
Il contributo, a partire da una recente pronuncia del Tribunale di Catanzaro, affronta la questione dei margini di discrezionalità della pubblica amministrazione reclutante nei procedimenti di mobilità individuale volontaria ex art. 30 d.lgs. n. 165/2001, con specifico riferimento alla fase di valutazione delle competenze professionali dei candidati. Ciò offre l’occasione per soffermarsi sulla natura dell’istituto, anche alla luce dei più recenti approdi legislativi in materia.
The Psychological Science Accelerator’s COVID-19 rapid-response dataset
2023
Funder: Amazon Web Services (AWS) Imagine Grant
Correcting for non-ignorable missingness in smoking trends
2015
Data missing not at random (MNAR) is a major challenge in survey sampling. We propose an approach based on registry data to deal with non-ignorable missingness in health examination surveys. The approach relies on follow-up data available from administrative registers several years after the survey. For illustration we use data on smoking prevalence in Finnish National FINRISK study conducted in 1972-1997. The data consist of measured survey information including missingness indicators, register-based background information and register-based time-to-disease survival data. The parameters of missingness mechanism are estimable with these data although the original survey data are MNAR. The u…
Automatic variable selection for exposure-driven propensity score matching with unmeasured confounders.
2020
Multivariable model building for propensity score modeling approaches is challenging. A common propensity score approach is exposure-driven propensity score matching, where the best model selection strategy is still unclear. In particular, the situation may require variable selection, while it is still unclear if variables included in the propensity score should be associated with the exposure and the outcome, with either the exposure or the outcome, with at least the exposure or with at least the outcome. Unmeasured confounders, complex correlation structures, and non-normal covariate distributions further complicate matters. We consider the performance of different modeling strategies in …
Robust dynamic cooperative games
2009
Classical cooperative game theory is no longer a suitable tool for those situations where the values of coalitions are not known with certainty. Recent works address situations where the values of coalitions are modelled by random variables. In this work we still consider the values of coalitions as uncertain, but model them as unknown but bounded disturbances. We do not focus on solving a specific game, but rather consider a family of games described by a polyhedron: each point in the polyhedron is a vector of coalitions’ values and corresponds to a specific game. We consider a dynamic context where while we know with certainty the average value of each coalition on the long run, at each t…
A Neo2 bayesian foundation of the maxmin value for two-person zero-sum games
1994
A joint derivation of utility and value for two-person zero-sum games is obtained using a decision theoretic approach. Acts map states to consequences. The latter are lotteries over prizes, and the set of states is a product of two finite sets (m rows andn columns). Preferences over acts are complete, transitive, continuous, monotonie and certainty-independent (Gilboa and Schmeidler (1989)), and satisfy a new axiom which we introduce. These axioms are shown to characterize preferences such that (i) the induced preferences on consequences are represented by a von Neumann-Morgenstern utility function, and (ii) each act is ranked according to the maxmin value of the correspondingm × n utility …
Bayesian models for data missing not at random in health examination surveys
2018
In epidemiological surveys, data missing not at random (MNAR) due to survey nonresponse may potentially lead to a bias in the risk factor estimates. We propose an approach based on Bayesian data augmentation and survival modelling to reduce the nonresponse bias. The approach requires additional information based on follow-up data. We present a case study of smoking prevalence using FINRISK data collected between 1972 and 2007 with a follow-up to the end of 2012 and compare it to other commonly applied missing at random (MAR) imputation approaches. A simulation experiment is carried out to study the validity of the approaches. Our approach appears to reduce the nonresponse bias substantially…