Search results for "Exchange"
showing 10 items of 2035 documents
Bitcoin e cyber self-laundering: lo sguardo sospettoso della Cassazione sull'impiego di criptovaluta
2023
In Judgment n. 27023 of 2022, the italian Supreme Court recognized the confgurability of the crime of self-money laundering in the conduct of a person who uses the proceeds of crimes committed by him to purchase bitcoin, not directly, but through the intermediation of cryptocurrency exchange companies. The Author takes the pronouncement as a starting point to probe the extent to which the culture of suspicion, with which the anti-money laundering legislation is imbued, and the stigmatization of cryptocurrency have influenced the Supreme Court's guidance, in which there emerges a strong temptation to establish a kind of automatism between the input of illicit proceeds into the bitcoin system…
Perceived Support in E-Collaborative Learning: An Exploratory Study Which Make Use of Synchronous and Asynchronous Online-Teaching Approaches
2012
This study compares four different learning environments for e-collaborative learning in two European countries related to the dimension of student's mutual support. The theoretical baseline is Vygotsky's zone of proximal development (ZOPD) and the socio-genetic approach of Piaget. The analyzed data are based on questionnaires collected over the time period of an entire semester including four different courses at the master's level. These courses applied different e-collaborative approaches including a variety of tools for supporting communication. It is assumed that these courses including communication tools e.g. virtual face-to-face meetings enhance the chances for better communication,…
Blockchain Securities, Insolvency Law and the Sandbox Approach
2018
Blockchain is a new technology that is based on an algorithm which allows participants of an IT network to process, store and share data across multiple points without the need for any intermediary, at least in order to ensure the integrity of the data dealt with. This technology is simplifying financial markets—many organizations are launching initial coin offerings to facilitate the financing of new business ventures; moreover, ‘securities’ that are issued in such a digital form can be bought and sold in the secondary market without the intervention of the traditional intermediaries. However, this use of blockchain could give rise to many problems which, in this article, will be analysed …
The effects of alpha-cypermethrin exposure on biochemical and redox parameters in pregnant rats and their newborns
2016
IF 2.388; International audience; Pyrethroid insecticides are extensively used in agriculture and in household activities. During pregnancy, they might affect maternal metabolic status and there after fetal development. In this work, we studied metabolic and redox effects of low dose alpha-cypermethrin exposure in pregnant rats and their offspring. The diet containing alpha cypermethrin at 0.02 mg/kg/day was consumed during the entire gestation. Plasma biochemical parameters as well as liver lipid and oxidative stress markers were determined. Our results showed that alpha-cypermethrin induced an increase in body weight and in plasma glucose and lipid levels, as well as in plasma aspartate a…
Acute Metabolic Response, Energy Expenditure, and EMG Activity in Sitting and Standing
2017
Purpose While merely standing up interrupts sedentary behavior, it is important to study acute metabolic responses during single bouts of sitting and standing to understand the physiological processes affecting the health of office workers. Methods Eighteen healthy middle-age women 49.4 ± 7.9 yr old (range: 40–64) with a body mass index of 23.4 ± 2.8 kg·m−2 volunteered for this laboratory-based randomized crossover trial where they performed 2 h desk work in either sitting or standing postures after overnight fasting. Muscle activity (normalized to walking at 5 km·h−1), respiratory gas exchange, and blood samples were assessed after glucose loading (75 g). Results Compared with seated work,…
Lipid metabolism during exercise
1980
Seven physically fit (well-trained, maximal oxygen uptake 69.6 +/- 4.4 ml x kg-1 min-1) and eight less fit (moderately trained, maximal oxygen uptake 56.1 +/- 5.7 ml x kg-1 x min-1) healthy male subjects were exercised for 4 h by bicycle ergometry against a pedalling resistance calculated to cause oxygen consumption corresponding to approximately 30% of each individual's maximal oxygen uptake value. Respiratory exchange ratio was estimated at 1 h and blood glucose and lactate concentrations and muscle glycogen content at 2 h intervals. Muscle glycogen content decreased markedly during the first 2 h of exercise in the well-trained group but was similar after 4 h exercise in both groups. No m…
Phosphorylation of CalDAG-GEFI by protein kinase A prevents Rap1b activation.
2013
Summary Background Signaling via protein kinase A (PKA) and protein kinase G (PKG) is critical for maintaining platelets in the resting state. Both kinases down-regulate the activity of the small GTPase Rap1b, a critical signaling switch for integrin activation and platelet aggregation. However, the mechanism of Rap1b regulation by PKA and PKG is largely unknown. Objective To identify the PKA phosphorylation sites in calcium and diacylglycerol-regulated guanine nucleotide exchange factor I (CalDAG-GEFI), the main GEF for Rap1b in platelets, and the effect of CalDAG-GEFI phosphorylation in Rap1b activation. Methods The phosphorylation sites in CalDAG-GEFI were identified by radio-active phos…
Therapeutic properties of haemodialysis and blood exchange transfusion in organophosphate poisoning
1976
Human blood was contaminated with nitrostigmine, dimethoate and demeton-S-methyl sulfoxide. It was then dialysed, concentrations of organophosphates were determined and dialysance values calculated. The influence of blood exchange transfusion on poison elimination as well as on the cholinesterase activity of blood, brain and muscle was studied in rats poisoned with nitrostigmine. Haemodialysis was found to be quite an effective method for eliminating demeton-S-methyl sulfoxide and dimethoate, dialysance values of 52.98 ml/min and 59.07 ml/min being found for demeton-S-methyl sulfoxide and dimethoate respectively. Nitrostigmine could not be removed by haemodialysis. These findings suggest th…
An Anthropometric Analysis of Seated and Standing People
2012
Thermal radiative exchanges of the human body with surrounding surfaces play an essential role in describing the thermal conditions of people in a given environment. Moreover, they could be induced by, among other causes, the presence of high intensity radiant sources, like lighting spots or infrared heating panels. This implies that a suitable set of radiation data related to human body anthropometry is required. This set of data mainly comprises the body surface area, the clothing area factor, the effective radiation area factor, and projected area factors. Several analytical or experimental methods may be utilized in order to compute these parameters. A detailed description of the most c…
Is the Border Effect an Artefact of Geographical Aggregation?
2011
The existence of a large border effect is considered as one of the main puzzles of international macroeconomics. We show that the border effect is, to a large extent, an artefact of geographic concentration. In order to do so we combine international flows with intra-national flows data characterised by a high geographic grid. At this fine grid, intra-national flows are highly localised and dropping sharply with distance. The use of a small geographical unit of reference to measure intra-national bilateral trade flows allows to estimating correctly the negative impact of distance on shipments. When we use sector disaggregated export flows of 50 Spanish provinces in years 2000 and 2005 split…