Search results for "Excretion"

showing 5 items of 145 documents

Effects of ipriflavone on bone mass and calcium metabolism in postmenopausal osteoporosis.

1992

Recently it has been demonstrated that ipriflavone (IP), an isoflavone derivative, is able to increase bone mass in patients with established postmenopausal osteoporosis (PMO). Here we present a preliminary report of a 2-year multicenter, double-blind, placebo-controlled clinical study performed in order to evaluate the efficacy and tolerability of IP in PMO. A large number of patients with PMO, referred to 12 Italian centers, was randomly divided into 2 groups and treated with oral IP (600 mg/day) or placebo (Pl). All patients received an oral Ca supplement (1 g/day). One hundred and twenty six patients completed 1 year of the study. Bone mineral density (BMD) of the distal radius, measure…

medicine.medical_specialtyUrinary systemOsteoporosisUrologyPlaceboBiochemistryExcretionEndocrinologyDouble-Blind MethodBone DensityInternal medicinemedicineHumansOsteoporosis PostmenopausalAgedBone mineralCalcium metabolismbusiness.industryMiddle Agedmedicine.diseaseIsoflavonesEndocrinologyItalyTolerabilityCalciumFemaleSurgeryIpriflavonebusinessmedicine.drug
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Antiketogene Wirkung von Xylit bei alloxandiabetischen Ratten

1963

Bei alloxandiabetischen Ratten mit Ketonurie zeigt Xylit je nach Versuchsbedingungen in 50–80% der Falle eine statistisch gesicherte antiketogene Wirkung.

medicine.medical_specialtybusiness.industryGeneral MedicineUrineXyloseXylitolmedicine.diseaseMolecular medicineExcretionchemistry.chemical_compoundEndocrinologychemistryInternal medicineAlloxanDiabetes mellitusDrug DiscoverymedicineMolecular MedicineMannitolbusinessGenetics (clinical)medicine.drugKlinische Wochenschrift
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Factors Predisposing to Hypertension in Subjects Formerly Born Preterm: Renal Impairment, Arterial Stiffness, Endothelial Dysfunction or 
Something E…

2020

: Subjects formerly born preterm subsequently develop arterial - particularly isolated systolic- hypertension more frequently than their peers born at term. : Numerous factors may influence this predisposition, including an incomplete nephrogenesis, implying the presence of kidneys with a reduced number of nephrons and consequent reduction in haematic filtration, increased sodium absorption and activation of renin-angiotensin-aldosterone system, increased arterial rigidity produced by an elastin deficiency previously observed in anatomic specimens of human immature aorta, and reduced endothelial nitric oxide excretion, due to high blood levels of ADMA, a strong direct inhibitor of nitric o…

medicine.medical_specialtyhypertensionIntrauterine growth restrictionGestational Age030204 cardiovascular system & hematologyKidneyRisk AssessmentArticleNitric oxideExcretion03 medical and health scienceschemistry.chemical_compound0302 clinical medicineVascular StiffnessRisk FactorsInternal medicinemedicine.arteryInternal MedicineMedicineHumans030212 general & internal medicinelow birth weightEndothelial dysfunctionAortaFetal Growth Retardationbiologybusiness.industryInfant Newbornpreterm birthblood pressureperinatal programmingmedicine.diseaseEndocrinologyBlood pressurechemistryArterial stiffnessbiology.proteinEndothelium VascularbusinessPrematurityElastinInfant PrematureCurrent Hypertension Reviews
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The Relationship between the Transforming Growth Factor β1 T29C Gene Polymorphism and Left Ventricular Geometry and Function in Hypertensive Subjects

2009

The distribution of the T29C TGFβ1 gene polymorphism was analyzed in 198 hypertensives with left ventricular hypertrophy (LVH) and in 235 hypertensives without LVH. Circulating TGFβ1 levels, procollagen type III levels, microalbuminuria, and left ventricular geometry and function were evaluated in all the hypertensives with LVH subgrouped according to T29C TGFβ1 gene polymorphism. Circulating TGFβ1 was evaluated by ELISA technique, procollagen type III by a specific radioimmunoassay, microalbuminuria by radioimmunoassay, and left ventricular geometry and function by echocardiography. All groups were comparable for gender, age, and sex. Regarding T29C TGFβ1 gene polymorphism, prevalence of T…

medicine.medical_specialtylcsh:Diseases of the circulatory (Cardiovascular) systemSettore MED/09 - Medicina InternaArticle SubjectLeft ventricular hypertrophyExcretionGene PolymorphismInternal medicineGenotypeInternal MedicinemedicineTransforming Growth Factor β1 T29C; Gene Polymorphism; Left Ventricular Geometry; Hypertensioncardiovascular diseasesTransforming Growth Factor β1 T29CEjection fractionbusiness.industryLeft Ventricular GeometryRadioimmunoassaymedicine.diseaseSettore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheSettore MED/11 - Malattie Dell'Apparato CardiovascolareEndocrinologylcsh:RC666-701HypertensionMicroalbuminuriaGene polymorphismbusinessResearch ArticleTransforming growth factorInternational Journal of Hypertension
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Biodegradable Ultrasmall-in-Nano Gold Architectures: Mid-Period In Vivo Distribution and Excretion Assessment

2018

theranosticsPeriod (periodic table)Chemistry02 engineering and technologyGeneral ChemistryBiodegradationgold010402 general chemistry021001 nanoscience & nanotechnologyCondensed Matter Physics01 natural sciencesbiodegradation0104 chemical sciencesExcretionIn vivoColloidal goldsilicaEnvironmental chemistryDistribution (pharmacology)General Materials Scienceexcretion0210 nano-technologybiodegradation; excretion; gold; silica; theranostics
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