Search results for "Exercise"

showing 10 items of 3151 documents

Early Effects of Sacubitril/Valsartan on Exercise Tolerance in Patients with Heart Failure with Reduced Ejection Fraction.

2019

Background. Sacubitril/valsartan in heart failure (HF) with reduced ejection fraction (HFrEF) was shown to be superior to enalapril in reducing the risk of death and hospitalization for HF. Our aim was to evaluate the cardiopulmonary effects of sacubitril/valsartan in patients with HFrEF. Methods. We conducted an observational study. Ninety-nine ambulatory patients with HFrEF underwent serial cardiopulmonary exercise tests (CPET) after initiation of sacubitril/valsartan in addition to recommended therapy. Results. At baseline, 37% of patients had New York Heart Association (NYHA) class III. After a median follow-up of 6.2 months (range 3&ndash

medicine.medical_specialtyOxygen pulselcsh:Medicineheart failure030204 cardiovascular system & hematologyArticleSacubitril03 medical and health sciences0302 clinical medicineInternal medicinemedicine030212 general & internal medicineEjection fractionbusiness.industrylcsh:RGeneral Medicinemedicine.diseaseBlood pressureValsartanHeart failuresacubitril/valsartanCardiologyexercise tolerancebusinessAnaerobic exerciseSacubitril Valsartanmedicine.drugcardiopulmonary test
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Physiopathological, Epidemiological, Clinical and Therapeutic Aspects of Exercise-Associated Hyponatremia.

2014

Exercise-associated hyponatremia (EAH) is dilutional hyponatremia, a variant of inappropriate antidiuretic hormone secretion (SIADH), characterized by a plasma concentration of sodium lower than 135 mEq/L. The prevalence of EAH is common in endurance (<6 hours) and ultra-endurance events (>6 hours in duration), in which both athletes and medical providers need to be aware of risk factors, symptom presentation, and management. The development of EAH is a combination of excessive water intake, inadequate suppression of the secretion of the antidiuretic hormone (ADH) (due to non osmotic stimuli), long race duration, and very high or very low ambient temperatures. Additional risk factors …

medicine.medical_specialtyPathologyhyponatremiaexercisebusiness.industryNausealcsh:RSIADHlcsh:MedicineGeneral MedicineReviewmedicine.diseaseHypertonic salineCerebral edemaRespiratory failureInternal medicineExercise-associated hyponatremiamedicineVomitingmedicine.symptombusinessHyponatremiahypertonic salineAntidiureticJournal of clinical medicine
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Dropout from exercise randomized controlled trials among people with depression: A meta-analysis and meta regression

2015

Abstract Objective Exercise has established efficacy in improving depressive symptoms. Dropouts from randomized controlled trials (RCT’s) pose a threat to the validity of this evidence base, with dropout rates varying across studies. We conducted a systematic review and meta-analysis to investigate the prevalence and predictors of dropout rates among adults with depression participating in exercise RCT’s. Method Three authors identified RCT’s from a recent Cochrane review and conducted updated searches of major electronic databases from 01/2013 to 08/2015. We included RCT’s of exercise interventions in people with depression (including major depressive disorder (MDD) and depressive symptoms…

medicine.medical_specialtyPatient DropoutseducationDepression Exercise Physical activity DropoutPsychological interventionlaw.inventionRandomized controlled triallawPrevalencemedicineHumansMeta-regressionExerciseDepression (differential diagnoses)Dropout (neural networks)Randomized Controlled Trials as TopicDepressive Disorder MajorDepressive DisorderDepressionPhysical activityDropoutMajormedicine.diseaseExercise TherapyPsychiatry and Mental healthClinical PsychologyMeta-analysisPhysical therapyMajor depressive disorderDepression; Dropout; Exercise; Physical activity; Depression; Depressive Disorder Major; Humans; Patient Dropouts; Prevalence; Randomized Controlled Trials as Topic; Exercise Therapy; Psychiatry and Mental Health; Clinical PsychologyExercise prescriptionPsychology
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Fructose 2,6-bisphosphate and glycolytic flux in skeletal muscle of swimming frog

1990

AbstractGlycolytic flux in skeletal muscle is controlled by 6-phosphofructokinase but how this is achieved is controversial. Brief exercise (swimming) in frogs caused a dramatic increase in the phosphofructokinase activator, fructose 2,6-bisphosphate, in working muscle. The kinetics of phosphofructokinase suggest that in resting muscle, the enzyme is inhibited by ATP plus citrate and that the increase in fructose 2,6-bisphosphate is part of the mechanism to activate phosphofructokinase when exercise begins. When exercise was sustained, fructose 2,6-bisphosphate in muscle was decreased as was the rate of lactate accumulation. Glycolytic flux and the content of fructose 2,6-bisphosphate appea…

medicine.medical_specialtyPhosphofructokinase-1Rana temporariaBiophysicsSkeletal musclePhysical exerciseMotor ActivityBiologyBiochemistrychemistry.chemical_compoundStructural BiologyInternal medicineFructosediphosphatesGeneticsmedicineAnimalsGlycolysisLactic AcidExerciseMolecular BiologySwimmingchemistry.chemical_classificationMusclesSkeletal muscleFructoseCell BiologyEnzyme ActivationKineticsFructose 26-bisphosphateEndocrinologymedicine.anatomical_structureEnzymeBiochemistrychemistryFructose 26-bisphosphateLactates6-PhosphofructokinaseAnuraHexosediphosphatesGlycolysisFlux (metabolism)PhosphofructokinaseFEBS Letters
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Tensiomyography reliability and prediction of changes in muscle force following heavy eccentric strength exercise using muscle mechanical properties

2015

AbstractThe current study involved the completion of two distinct experiments. Experiment 1 analyzed the inter-day reliability of tensiomyography (TMG) muscle mechanical properties based on the amplitude of the muscle belly radial deformation, the time it takes to occur, and its velocity under maximal and submaximal stimuli, in the muscles rectus femoris, biceps femoris, and gastrocnemius lateralis, from 20 male sport students. Experiment 2 investigated whether changes in maximal voluntary isometric contraction (MVIC) could be predicted based on changes in TMG properties following 24 h after different squat training protocols (MS = multiple sets; DS = drop sets; EO = eccentric overload; FW …

medicine.medical_specialtyPhysical Therapy Sports Therapy and RehabilitationHuman Factors and ErgonomicsMuscle bellySquat030229 sport sciencesAnatomyIsometric exerciseEccentric strengthBicepsTensiomyography03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationmedicineOrthopedics and Sports MedicineEngineering (miscellaneous)030217 neurology & neurosurgeryReliability (statistics)MathematicsMuscle forceSports Technology
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The Phys-Can observational study: adjuvant chemotherapy is associated with a reduction whereas physical activity level before start of treatment is a…

2020

AbstractBackgroundAdjuvant therapy may cause multiple sideeffects on long term health, including reduced cardiorespiratory fitness (CRF) in patients with breast cancer (1, 2). However, there is currently limited knowledge regarding the effect of different types of adjuvant cancer treatment on CRF in other cancer populations. The primary objective of the present study was to assess whether previously known correlates (age, diagnosis, initial CRF, physical activity level), type of adjuvant treatment and cancer-related fatigue were associated with changes in$$ \dot{V}{O}_2\mathit{\max} $$V̇O2maxin patients with breast, prostate or colorectal cancer.MethodsProspective study with two time points…

medicine.medical_specialtyPhysical Therapy Sports Therapy and RehabilitationType (model theory)GastroenterologyIncremental exercise03 medical and health sciences0302 clinical medicineBreast cancerInternal medicinemedicineAdjuvant therapyOrthopedics and Sports Medicine030212 general & internal medicinelcsh:Sports medicineProspective cohort studyCancer-related fatigueCancer related fatigueOncological treatmentPhysical activitybusiness.industryRehabilitationVO2 maxPublic Health Global Health Social Medicine and Epidemiology030229 sport sciencesVDP::Medisinske Fag: 700::Idrettsmedisinske fag: 850medicine.diseaseConfidence intervalCardiopulmonary exercise testingFolkhälsovetenskap global hälsa socialmedicin och epidemiologimedicine.symptomlcsh:RC1200-1245businessResearch ArticleBMC Sports Science, Medicine and Rehabilitation
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Depression mediates physical activity readiness and physical activity in patients with heart failure.

2021

Aims Although physical activity (PA) and exercise are essential for patients with heart failure (HF), adherence to the recommended guidelines is low. Not much is known about the mediating effect of HF patients mental state with their readiness for PA and reported activity levels. The purpose of this study is to investigate the mediatory effect of depression on PA readiness (physical limitation and psychological readiness) and self-reported PA in patients with HF. Methods and results In this cross-sectional study, 163 New York Heart Association Class I and II HF patients, during their clinic visit, reported on their physical limitation (PAR-Q) and psychological readiness [self-efficacy (ESES…

medicine.medical_specialtyPhysical activityDiseases of the circulatory (Cardiovascular) systemMedicineHumansIn patientSjukgymnastikPhysiotherapyExerciseDepression (differential diagnoses)Heart failure; Depression; Physical activity; Readiness; Motivation; Self-efficacyNew York Heart Association Class ISelf-efficacyHeart FailureMotivationbusiness.industryDepressionPhysical activityDepression Heart failure Motivation Physical activity Readiness Self-efficacyOriginal Articlesmedicine.diseaseReadinessPhysical limitationsCross-Sectional StudiesRC666-701Mental stateHeart failurePhysical therapyOriginal ArticleSelf ReportCardiology and Cardiovascular MedicinebusinessSelf‐efficacyESC heart failure
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Beneficial Effects of Inspiratory Muscle Training Combined With Multicomponent Training in Elderly Active Women

2019

ABSTRACTPurpose: This study aims to analyze changes in Maximum Inspiratory Pressure (MIP), lung function, cardiorespiratory fitness, and blood pressure, in 10 healthy active elderly women, followin...

medicine.medical_specialtyPhysical fitnessBlood Pressure030209 endocrinology & metabolismPhysical Therapy Sports Therapy and RehabilitationPhysical strengthBreathing Exercises03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationHumansMedicineOrthopedics and Sports MedicineMuscle StrengthCardiovascular fitnessBeneficial effectsLung functionAgedbusiness.industryInspiratory muscle trainingCardiorespiratory fitness030229 sport sciencesGeneral MedicineRespiratory MusclesBlood pressureCardiorespiratory FitnessInhalationNephrologyFemalesense organsbusinessPhysical Conditioning HumanResearch Quarterly for Exercise and Sport
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Twelve-Week Internet-Based Individualized Exercise Program in Adults With Systemic Lupus Erythematosus: Protocol for a Randomized Controlled Trial

2020

Background Systemic lupus erythematosus is a systemic autoimmune disease, which is associated with high cardiovascular risk, a predisposition to metabolic disorders, muscle wasting, and fatigue. Exercise therapy has become an important part of the long-term treatment of comorbidities in systemic lupus erythematosus. Exercise can lead to various benefits in patients with systemic lupus erythematosus such as increased aerobic capacity and exercise tolerance, resulting in an increased quality of life, decreased depression, and decreased fatigue. At the moment, no evidence-based treatment guidelines that recommend exercise for patients with systemic lupus erythematosus exist. Also, the efficac…

medicine.medical_specialtyPhysical fitnessComputer applications to medicine. Medical informaticsR858-859.7physical activitylaw.invention03 medical and health sciences0302 clinical medicinesystemic lupus erythematosusQuality of lifeRandomized controlled triallawinternet-based exercise program disease activityInternal medicineProtocolmedicineAerobic exerciseOutpatient clinic030212 general & internal medicineWasting030203 arthritis & rheumatologybusiness.industryRGeneral MedicineRheumatologyMedicinefatiguemedicine.symptombusinessAnaerobic exerciseJMIR Research Protocols
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Subgrouping and targeted exercise programmes for knee and hip osteoarthritis (STEER OA) individual participant data meta-analysis. Progress update an…

2019

medicine.medical_specialtyPhysical medicine and rehabilitationRheumatologybusiness.industryMeta-analysisTherapeutic exerciseIndividual participant dataBiomedical EngineeringmedicineHip osteoarthritisOrthopedics and Sports MedicinebusinessSelection (genetic algorithm)Osteoarthritis and Cartilage
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