Search results for "Exposure"
showing 10 items of 1125 documents
Cadmium and lead in infant cereals — electrothermal-atomic absorption spectroscopic determination
1999
Because infant cereals are an important component of the infant diet from the fourth month of life onwards and therefore contribute to the dietetic intake of metals by infants, cadmium and lead were measured in samples of cereals commercially available in Spain. For this purpose an electrothermal atomic absorption (ET-AAS) method for determining cadmium and lead in these products was studied. The ET-AAS instrumental conditions and temperature/time furnace program were selected. The analytical parameters of the method (linearity, detection and quantification limits and precision) show its usefulness in measuring cadmium and lead in infant cereal products. The method was applied to eight diff…
Chronic exposure to glucocorticoids induces suboptimal decision-making in mice.
2021
AbstractAnxio-depressive symptoms as well as severe cognitive dysfunction including aberrant decision-making (DM) are documented in neuropsychiatric patients with hypercortisolaemia. Yet, the influence of the hypothalamo-pituitary-adrenal (HPA) axis on DM processes remains poorly understood. As a tractable mean to approach this human condition, adult male C57BL/6JRj mice were chronically treated with corticosterone (CORT) prior to behavioural, physiological and neurobiological evaluation. The behavioural data indicate that chronic CORT delays the acquisition of contingencies required to orient responding towards optimal DM performance in a mouse Gambling Task (mGT). Specifically, CORT-treat…
Occurrence of biomarkers of pesticide exposure in non-invasive human specimens.
2015
Biomonitoring has been used in many types of investigations, including national programmes and epidemiological studies, to explore the occurrence of biomarkers of pesticide exposure in the general population or relevant groups. This review discusses recent studies that measure levels of biomarkers of pesticide exposure in non-invasive human specimens such as urine, breast milk, meconium and hair. Specific and non-specific metabolites of organophosphate and pyrethroid insecticides have been widely investigated in urine, where some of the suitable biomarkers present rates of detection higher than 80%, which stand for an ongoing chronic exposure to traces of these chemicals. Hair is a promisin…
Biopartitioning micellar chromatography to pedict mutagenicity of aromatic amines
2007
[EN] Mutagenicity is a toxicity endpoint associated with the chronic exposure to chemicals. Aromatic amines have considerable industrial and environmental importance due to their widespread use in industry and their mutagenic capacity. Biopartitioning micellar chromatography (BMC), a mode of micellar liquid chromatography that uses micellar mobile phases of Brij35 in adequate experimental conditions, has demonstrated to be useful in mimicking the drug partitioning process into biological systems. In this paper, the usefulness of BMC for predicting mutagenicity of aromatic amines is demonstrated. A multiple linear regression (MLR) model based on BMC retention data is proposed and compared wi…
Chronic exposure to a GSM-like signal (mobile phone) does not stimulate the development of DMBA-induced mammary tumors in rats: results of three cons…
2002
Certain epidemiological and experimental studies raised concerns about the safety of radiofrequency (RF) electromagnetic fields because of a possible increased risk of leukemia and lymphoma. In this study, an RF field used in mobile telecommunication was tested using 7,12-dimethylbenz[a]anthracene (DMBA)-induced mammary tumors in female Sprague-Dawley rats as a model for human breast cancer. Three experiments were carried out under strictly standardized conditions and were started on the same day of three consecutive years. The field consisted of a GSM-like signal (900 MHz pulsed at 217 Hz, pulse width 577 micros) of relatively low power flux density (100 microW/cm(2) +/- 3 dB) and was appl…
Ischemic cardiovascular disease in workers occupationally exposed to urban air pollution – A systematic review
2018
Introduction Cardiovascular disease is the first cause of morbidity and mortality worldwide. Among several known risk factors, researchers also focus their attention on the chronic exposure to air pollution. There is much evidence that exposure to air pollution, especially to ultrafine particles, can damage the endothelium and can favour cardiovascular diseases in the general population. Occupational exposition could be an additive risk factor for the cardiovascular system. This article presents a scientific review of the linkage between occupational exposure to air pollution and ischemic heart disease. Material and methods A scientific review was undertaken, followed by PRISMA Statements. …
Binge-Like, Naloxone-Sensitive, Voluntary Ethanol Intake at Adolescence Is Greater Than at Adulthood, but Does Not Exacerbate Subsequent Two-Bottle C…
2020
The present study assessed the effects of ethanol exposure during adolescence or adulthood. We exposed Wistar rats, males or females, to self-administered 8–10% (v/v) ethanol (BINGE group) during the first 2 h of the dark cycle, three times a week (Monday, Wednesday, and Friday) during postnatal days (PDs) 32–54 or 72–94 (adolescent and adults, respectively). During this period, controls were only handled, and a third (IP) condition was given ethanol intraperitoneal administrations, three times a week (Monday, Wednesday, and Friday), at doses that matched those self-administered by the BINGE group. The rats were tested for ethanol intake and preference in a two-bottle (24 h long) choice tes…
TREC: A tool kit for programming cognitive experiments in Applesoft BASIC
1987
Partisanship, Ideology, and Selective Exposure: A Longitudinal Analysis of Media Consumption in Spain (2008–2019)
2022
La literatura sobre exposición selectiva ha demostrado que la ideología y el voto gobiernan las decisiones de consumo de medios, pero los estudios longitudinales aún son escasos. Para llenar este vacío, este trabajo analiza: (a) si la exposición selectiva guiada por la ideología y el partidismo a tres tipos de medios (televisión, radio y periódicos) es un fenómeno estable en España (2008-2019) como se espera de un medio pluralista polarizado. sistema; y (b) qué variable tiene los efectos más fuertes en las elecciones de noticias (ideología o partidismo). Se realizan regresiones logísticas multinomiales utilizando fuentes de datos de seis encuestas postelectorales realizadas por el Centro de…
Influencia del perfil sociodemográfico relaciones con el medio y actitud ante la compra a distancia en el comportamiento de compra por television
2007
El objetivo de la presente investigación es profundizar en el estudio de los factores determinantes del comportamiento de compra a través de la televisión. Con este fin, se plantean un conjunto de hipótesis sobre la influencia del perfil sociodemográfico, la exposición al medio televisivo y al género de compra televisiva y la actitud ante el sistema, en la decisión de compra por televisión. Del análisis de resultados obtenidos de una muestra de 200 telecompradores españoles, se pone de manifiesto que la exposición al género de compra por televisión y la actitud ante el sistema son predictores significativos del comportamiento de compra a través de la televisión. / This paper aims to present…