Search results for "Exposure"

Zilās gaismas draudu kumulatīvā analīze

2022

Maģistra darbs uzrakstīts angļu valodā uz 42 lappusēm. Tas satur 15 attēlus, 4 vienadojumi, 8 tabulas un 64 atsauces. Cilvēki katru dienu ir pakļauti zilajai gaismai. Zilā gaisma ir bīstama, ja tā pārsniedz 100 J / (cm2-sr) uz 106 ≤ t. Pirmsreceptoru makulas pigmenti, luteīns un zeaksantīns kopā ar lēcas kristālu absorbē zilo gaismu. Zilās gaismas svērtais spožums dažādos ekspozīcijas ilgumos tika modelēts ar doto datu bāzi, kas ņemta no f. fluxometrs dažādiem zilās gaismas avotiem. Rezultāti parādīja, ka gaismai, ko izstaro saules gaisma, īpaši saulainās dienās, ir visaugstākās zilās gaismas spožuma vērtības un tā tiek uzskatīta par kaitīgu, bet tomēr nepārsniedz vērtības, kas pierāda bīst…

Efficacy of four cleaning solutions for the decontamination of selected cytotoxic drugs on the different surfaces of an automated compounding system

2018

The automated aseptic preparation of ready-to-administer antineoplastic drug solutions with robotic systems reduces the risk of occupational exposure. However, the surfaces in the preparation area of the robot are to be cleaned by wiping with an appropriate cleaning solution. The aim of the study was to evaluate the cleaning efficacy of four cleaning solutions on four surface materials installed in the APOTECAchemo robot. Predefined amounts of cisplatin (Cis), 5-fluorouracil (5-FU), and cyclophosphamide (CP) were intentionally spread on test plates made of stainless steel, aluminium, polyoxymethylene, and polycarbonate just as installed in the robotic system APOTECAchemo. After drying, the …

Maternal occupational exposure to chemicals and neurocognitive development at 4-5 years of age

2021

A job-exposure matrix for research and surveillance of occupational health and safety in Spanish workers: MatEmESp

2013

BACKGROUND: In this study we describe a general-population job-exposure matrix (MatEmESp) for Spanish workers covering the period 1996-2005. METHODS: The Finnish job-exposure matrix (FINJEM) provided the default value estimates for occupational exposure to chemical, physical and biological agents. These estimates were adapted to Spanish working conditions by local experts. Spanish surveys were used to obtain exposure estimates for ergonomic and psychosocial risk factors. Employment and socio-demographic conditions for Spanish workers were obtained from the Spanish National Statistics Institute. RESULTS: MatEmESp provides a large amount of national and occupation-specific data on the major o…

Cognitive impairment associated with chronic lead exposure in adults

2018

Abstract Lead (Pb) exposure interferes with many biochemical events present in cells of the central nervous system (neurons and astrocytes) and it can produce a wide spectrum of alterations including cognitive impairment. The review summarizes the main cognitive alterations induced by chronic Pb exposure in adults/older individuals. We have focused on the current state of knowledge concerning the most vulnerable brain areas to Pb exposure that accompanied by the long-lasting neurological effects of Pb in cognitive functions. We tried to correlate the cognitive deficits induced by Pb exposure in animal models during adulthood with those reported in humans. The great interest in whether expos…

Long-Term Exposure to Transportation Noise and Risk for Type 2 Diabetes in a Nationwide Cohort Study from Denmark

2021

Background: Epidemiologic studies have linked transportation noise to increased morbidity and mortality, particularly for cardiovascular outcomes. However, studies investigating metabolic outcomes such as diabetes are limited and have focused only on noise exposures estimated for the loudest residential façade. Objectives: We aimed to examine the influence of long-term residential exposure to transportation noise at the loudest and quietest residential façades and the risk for type 2 diabetes. Methods: Road traffic and railway noise exposures (Lden) at the most and least exposed façades were estimated for all dwellings in Denmark during 1990–2017. Aircraft noise was estimated in 5-dB catego…

Astrocytes play an active role in persistence of respiratory augmentation in the recovery phase after hypoxic exposure

2020

128 Development of a job-exposure matrix (JEM) to describe pesticide exposure in Spanish workers (1996–2005)

2013

Objectives Pesticides are intensively used in Spain in a wide range of economic activities such as agriculture, farming, wood treatments or pest control, reaching in 2005 a consumption of more than 100,000 ton/year. Exposure to these substances has been proven to have negative effects on human health. However, there is little information available regarding the levels and frequency of exposure for workers, or the job titles associated with the worst exposure indicators. This study aimed to collect the available information on occupational pesticide exposure in Spain as a job-exposure matrix (JEM). Methods The work was carried out in the context of MatEmESp Project, which aims to build a Spa…

Occupational hygiene in a Finnish drum composting plant

2005

Bioaerosols (microbes, dust and endotoxins) and volatile organic compounds (VOCs) were determined in the working air of a drum composting plant treating source-separated catering waste. Different composting activities at the Oulu drum composting plant take place in their own units separated by modular design and constructions. Important implication of this is that the control room is a relatively clean working environment and the risk of exposure to harmful factors is low. However, the number of viable airborne microbes was high both in the biowaste receiving hall and in the drum composting hall. The concentration (geometric average) of total microbes was 21.8 million pcs/m3 in the biowaste…

Prenatal exposure to cannabinoids evokes long-lasting functional alterations by targeting CB 1 receptors on developing cortical neurons

2015

The CB1 cannabinoid receptor, the main target of Δ(9)-tetrahydrocannabinol (THC), the most prominent psychoactive compound of marijuana, plays a crucial regulatory role in brain development as evidenced by the neurodevelopmental consequences of its manipulation in animal models. Likewise, recreational cannabis use during pregnancy affects brain structure and function of the progeny. However, the precise neurobiological substrates underlying the consequences of prenatal THC exposure remain unknown. As CB1 signaling is known to modulate long-range corticofugal connectivity, we analyzed the impact of THC exposure on cortical projection neuron development. THC administration to pregnant mice in…